CYC7_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CYC7_YEAST
• UniProt AC: P00045
• Protein Name: Cytochrome c iso-2
• Gene Name: CYC7
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 113
• Subcellular Localization: Mitochondrion intermembrane space .
• Protein Description: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain..
• Protein Sequence: MAKESTGFKPGSAKKGATLFKTRCQQCHTIEEGGPNKVGPNLHGIFGRHSGQVKGYSYTDANINKNVKWDEDSMSEYLTNPKKYIPGTKMAFAGLKKEKDRNDLITYMTKAAK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Ubiquitination	AKESTGFKPGSAKKG CCCCCCCCCCCCCCC	50.22	-
12	Phosphorylation	STGFKPGSAKKGATL CCCCCCCCCCCCCEE	45.50	27717283
14	Ubiquitination	GFKPGSAKKGATLFK CCCCCCCCCCCEEEE	54.13	-
65	2-Hydroxyisobutyrylation	YTDANINKNVKWDED EECCCCCCCCCCCCC	60.36	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CYC7_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CYC7_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CYC7_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
URE2_YEAST	URE2	physical	18467557
DBP3_YEAST	DBP3	physical	18467557
COX14_YEAST	COX14	genetic	23897805

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.