STR3_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: STR3_YEAST
• UniProt AC: P53101
• Protein Name: Cystathionine beta-lyase
• Gene Name: STR3
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 465
• Subcellular Localization: Cytoplasm . Nucleus .
• Protein Sequence: MPIKRLDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGKYLFNKLNKNLAVNTTIDDLHKPLSIYEEFYNQDLIRKDSELNIKSSKL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
213	N6-(pyridoxal phosphate)lysine	VVYESATKYLNGHHD EEEEHHHHHHCCCCC	47.67	-
213	Other	VVYESATKYLNGHHD EEEEHHHHHHCCCCC	47.67	-
243	Phosphorylation	KLYFVINSTGAGLSP HEEEEECCCCCCCCH	19.66	27017623
244	Phosphorylation	LYFVINSTGAGLSPM EEEEECCCCCCCCHH	26.94	27017623
456	Phosphorylation	QDLIRKDSELNIKSS CHHHHCCCCCCCCCC	47.20	27214570

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of STR3_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of STR3_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of STR3_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TPS1_YEAST	TPS1	genetic	20093466
MBA1_YEAST	MBA1	genetic	20093466
ASK10_YEAST	ASK10	genetic	20093466
PHB2_YEAST	PHB2	genetic	20093466
ATP10_YEAST	ATP10	genetic	20093466
COX7_YEAST	COX7	genetic	20093466
EOS1_YEAST	EOS1	genetic	20093466
PET8_YEAST	PET8	genetic	20093466
ATP23_YEAST	ATP23	genetic	20093466
HMI1_YEAST	HMI1	genetic	20093466
CY1_YEAST	CYT1	genetic	20093466
COX6_YEAST	COX6	genetic	21623372
QCR9_YEAST	QCR9	genetic	21623372
PPT2_YEAST	PPT2	genetic	21623372
6PGD1_YEAST	GND1	genetic	21623372
IPT1_YEAST	IPT1	genetic	21623372
GSH1_YEAST	GSH1	genetic	21623372
THDH_YEAST	ILV1	genetic	21623372
ATPO_YEAST	ATP5	genetic	21623372
PDC6_YEAST	PDC6	genetic	21623372
COX7_YEAST	COX7	genetic	21623372
ARE1_YEAST	ARE1	genetic	21623372
COQ4_YEAST	COQ4	genetic	21623372
ERD2_YEAST	ERD2	genetic	27708008
MED8_YEAST	MED8	genetic	27708008
GLE1_YEAST	GLE1	genetic	27708008
RMRP_YEAST	SNM1	genetic	27708008
PRP19_YEAST	PRP19	genetic	27708008
NEP1_YEAST	EMG1	genetic	27708008
TAD3_YEAST	TAD3	genetic	27708008
MCM1_YEAST	MCM1	genetic	27708008
NOP2_YEAST	NOP2	genetic	27708008
OST2_YEAST	OST2	genetic	27708008
RPB2_YEAST	RPB2	genetic	27708008
MED4_YEAST	MED4	genetic	27708008
TF2B_YEAST	SUA7	genetic	27708008
HAP3_YEAST	HAP3	genetic	27708008
RL4A_YEAST	RPL4A	genetic	27708008
MBA1_YEAST	MBA1	genetic	27708008
NTM1_YEAST	TAE1	genetic	27708008
RV161_YEAST	RVS161	genetic	27708008
SNT1_YEAST	SNT1	genetic	27708008
MTU1_YEAST	SLM3	genetic	27708008
GPR1_YEAST	GPR1	genetic	27708008
PEX19_YEAST	PEX19	genetic	27708008
NDH2_YEAST	NDE2	genetic	27708008
BCS1_YEAST	BCS1	genetic	27708008
COX23_YEAST	COX23	genetic	27708008
SFK1_YEAST	SFK1	genetic	27708008
ATP10_YEAST	ATP10	genetic	27708008
MSS1_YEAST	MSS1	genetic	27708008
COX7_YEAST	COX7	genetic	27708008
EOS1_YEAST	EOS1	genetic	27708008
ATP23_YEAST	ATP23	genetic	27708008
HMI1_YEAST	HMI1	genetic	27708008
MNE1_YEAST	MNE1	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.