ENV7_YEAST - dbPTM
ENV7_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ENV7_YEAST
UniProt AC Q12003
Protein Name Serine/threonine-protein kinase ENV7
Gene Name ENV7
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 364
Subcellular Localization Vacuole membrane
Peripheral membrane protein .
Protein Description Serine/threonine-protein kinase involved in vacuolar processing and morphology..
Protein Sequence MISIVLELFQNLCCCRGFSDATIRVNDKRYRIQRLLGEGGMSFVYLVQLSKNSLIIDNGIATPELYALKKIICPSVESISNGMREIENYKRFQSPYVIKSIDSQVMQEKDGSKTIYIVLPYYSLGSLQDSINRRLLEGTFVSEAECVRIMLGVTRGLLCLHDPASRQDNATSRVNVDAVSMTYSDETAMLLEDTPLEMDMLSSNSAGSIAYAHRDITPSNILFSSDGLPVIGDLGSCSQADITIENRHQLSELQEWVNDNCTLPYTPPELLNLKLNQVLSSKVDIWSLGCTFYTLMFGISPFEREEQIHGASLTYAINTGKYSFPRNSRFSEGLLSVIKKCIQVDPIQRPTTSQLLNLLQDLDT
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
13S-palmitoylationLELFQNLCCCRGFSD
HHHHHHHHCCCCCCC		2.4324610781
14S-palmitoylationELFQNLCCCRGFSDA
HHHHHHHCCCCCCCC		1.6824610781
15S-palmitoylationLFQNLCCCRGFSDAT
HHHHHHCCCCCCCCE		4.6824610781
116PhosphorylationKDGSKTIYIVLPYYS
CCCCEEEEEEEECCC		7.1029650682
121PhosphorylationTIYIVLPYYSLGSLQ
EEEEEEECCCCCCHH		11.0929650682
122PhosphorylationIYIVLPYYSLGSLQD
EEEEEECCCCCCHHH		8.7629650682
205PhosphorylationMDMLSSNSAGSIAYA
HHCCCCCCCCCCEEE		35.6327214570
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ENV7_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ENV7_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ENV7_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
UFD2_YEASTUFD2physical
11805837
AHC1_YEASTAHC1genetic
21127252
CBF1_YEASTCBF1genetic
21127252
STP2_YEASTSTP2genetic
21127252
CBPY_YEASTPRC1physical
23166297
ENV7_YEASTENV7physical
23166297
H1_YEASTHHO1physical
23166297
H2A1_YEASTHTA1physical
23166297
H3_YEASTHHT1physical
23166297
YGN8_YEASTYGL138Cgenetic
22282571
YEF1_YEASTYEF1genetic
22282571
MSA2_YEASTMSA2genetic
22282571
RT109_YEASTRTT109genetic
22282571
TPS1_YEASTTPS1genetic
22282571
RIM15_YEASTRIM15genetic
22282571
VPS51_YEASTVPS51genetic
22282571
ATG9_YEASTATG9genetic
22282571
TCB1_YEASTTCB1genetic
22282571
PEX18_YEASTPEX18genetic
22282571
AZF1_YEASTAZF1genetic
22282571
ELP4_YEASTELP4genetic
22282571
ARO8_YEASTARO8genetic
22282571
AIM39_YEASTAIM39genetic
22282571
YKH5_YEASTYKL075Cgenetic
22282571
RAD51_YEASTRAD51genetic
22282571
STP1_YEASTSTP1genetic
22282571
HPF1_YEASTHPF1genetic
22282571
KC13_YEASTYCK3genetic
24345185
CSN12_YEASTYJR084Wgenetic
27708008
RIM1_YEASTRIM1genetic
27708008
GPR1_YEASTGPR1genetic
27708008
ATG9_YEASTATG9genetic
27708008
RL41A_YEASTRPL41Agenetic
27708008
RL41B_YEASTRPL41Agenetic
27708008
DOS2_YEASTDOS2genetic
27708008
RIM15_YEASTRIM15genetic
27708008
DBP3_YEASTDBP3genetic
27708008
ARO8_YEASTARO8genetic
27708008
ACBP_YEASTACB1genetic
27708008
ASK10_YEASTASK10genetic
27708008
GSH1_YEASTGSH1genetic
27708008
YKH5_YEASTYKL075Cgenetic
27708008
CBT1_YEASTCBT1genetic
27708008
VPS51_YEASTVPS51genetic
27708008
RT109_YEASTRTT109genetic
27708008
VPS9_YEASTVPS9genetic
27708008
ALG12_YEASTALG12genetic
27708008
INO4_YEASTINO4genetic
27708008
BUB3_YEASTBUB3genetic
27708008
AZF1_YEASTAZF1genetic
27708008
KIN4_YEASTKIN4genetic
27708008
YO304_YEASTBIL1genetic
27708008
SNU66_YEASTSNU66genetic
27708008
MNE1_YEASTMNE1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ENV7_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-205, AND MASSSPECTROMETRY.

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