KYNU_YEAST - dbPTM
KYNU_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID KYNU_YEAST
UniProt AC Q05979
Protein Name Kynureninase {ECO:0000255|HAMAP-Rule:MF_03017}
Gene Name BNA5 {ECO:0000255|HAMAP-Rule:MF_03017}
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 453
Subcellular Localization Cytoplasm . Nucleus .
Protein Description Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively..
Protein Sequence MEKALELDGEYPESLRDEFNIPTFKSMGLSSDDKPVTYLCGNSLGLMPKSTRNSINAELDAWSDCAVESHFKHPEEARGKVPWVSIDLPILPLLAPIVGAQENEVAVMNSLTANLNSLLITFYKPTEKRFKILFEKGSFPSDYYAFYNQCKIHGISEPENVFIQIEPREGETYIRTQDILDTIEVNQDELALVCLSGVQYYTGQYFDIGRITSFAHQFPDILVGWDLAHAVGNVPLQLHDWGVDFACWCSYKYLNAGPGGIGGLFVHSKHTKPDPAKESLPRLAGWWGNDPAKRFQMLEVFEPIPGALGFRQSNPSVIDTVALRSSLELFAKFNGINEVRKRSLLLTNYMTELLEASKYYKHPLRIEKLPCFFTILTPTSTDEEHGAQLSLYFDSDTGKEDIMPKVFQYLHDHGVIGDARRPNVIRLAPAPLYNTFSDVYIAVNALNEAMDKL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
252N6-(pyridoxal phosphate)lysineFACWCSYKYLNAGPG
EEEEEECCHHCCCCC		27.28-
252OtherFACWCSYKYLNAGPG
EEEEEECCHHCCCCC		27.28-
313PhosphorylationGALGFRQSNPSVIDT
CCCCCCCCCCHHHHH		46.5930377154
347PhosphorylationRKRSLLLTNYMTELL
HHHHHHHHHHHHHHH		25.0326447709
349PhosphorylationRSLLLTNYMTELLEA
HHHHHHHHHHHHHHH		10.5226447709
351PhosphorylationLLLTNYMTELLEASK
HHHHHHHHHHHHHHH		17.0824603354
357PhosphorylationMTELLEASKYYKHPL
HHHHHHHHHHCCCCC		16.3024603354
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of KYNU_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of KYNU_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of KYNU_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
HXKA_YEASTHXK1physical
16554755
TRX1_YEASTTRX1physical
16554755
ADH3_YEASTADH3physical
16554755
TNA1_YEASTTNA1genetic
21623372
NPT1_YEASTNPT1genetic
21623372
CEM1_YEASTCEM1genetic
21623372
DCOR_YEASTSPE1genetic
21623372
SLX5_YEASTSLX5genetic
27708008
SAC1_YEASTSAC1genetic
27708008
PMA2_YEASTPMA2genetic
27708008
HPC2_YEASTHPC2genetic
27708008
TNA1_YEASTTNA1genetic
27708008
DCOR_YEASTSPE1genetic
27708008
MAS5_YEASTYDJ1genetic
27708008
EOS1_YEASTEOS1genetic
27708008
YNO0_YEASTYNL140Cgenetic
27708008
VPS27_YEASTVPS27genetic
27708008
PEX15_YEASTPEX15genetic
27708008
DCAM_YEASTSPE2genetic
27708008
NPT1_YEASTNPT1genetic
27708008
GGPPS_YEASTBTS1genetic
27708008
SPEE_YEASTSPE3genetic
27708008
YP098_YEASTYPR098Cgenetic
27708008
VPS4_YEASTVPS4genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of KYNU_YEAST

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Related Literatures of Post-Translational Modification

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