GPI3_YEAST - dbPTM
GPI3_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GPI3_YEAST
UniProt AC P32363
Protein Name Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit
Gene Name SPT14
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 452
Subcellular Localization Endoplasmic reticulum membrane
Single-pass membrane protein .
Protein Description Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis..
Protein Sequence MGFNIAMLCDFFYPQLGGVEFHIYHLSQKLIDLGHSVVIITHAYKDRVGVRHLTNGLKVYHVPFFVIFRETTFPTVFSTFPIIRNILLREQIQIVHSHGSASTFAHEGILHANTMGLRTVFTDHSLYGFNNLTSIWVNKLLTFTLTNIDRVICVSNTCKENMIVRTELSPDIISVIPNAVVSEDFKPRDPTGGTKRKQSRDKIVIVVIGRLFPNKGSDLLTRIIPKVCSSHEDVEFIVAGDGPKFIDFQQMIESHRLQKRVQLLGSVPHEKVRDVLCQGDIYLHASLTEAFGTILVEAASCNLLIVTTQVGGIPEVLPNEMTVYAEQTSVSDLVQATNKAINIIRSKALDTSSFHDSVSKMYDWMDVAKRTVEIYTNISSTSSADDKDWMKMVANLYKRDGIWAKHLYLLCGIVEYMLFFLLEWLYPRDEIDLAPKWPKKTVSNETKEARET
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
139UbiquitinationLTSIWVNKLLTFTLT
CCHHHHHHHHHCCCC		34.9417644757
159UbiquitinationICVSNTCKENMIVRT
EEECCCCCCCCEEEE		50.5123749301
186UbiquitinationAVVSEDFKPRDPTGG
CEECCCCCCCCCCCC		52.0123749301
217PhosphorylationRLFPNKGSDLLTRII
CCCCCCCCHHHHHHH		27.0521126336
244UbiquitinationIVAGDGPKFIDFQQM
EECCCCCCEECHHHH		61.5517644757
347UbiquitinationAINIIRSKALDTSSF
HHHHHHHHCCCCCCC		43.0217644757
352PhosphorylationRSKALDTSSFHDSVS
HHHCCCCCCCHHHHH		30.5827017623
353PhosphorylationSKALDTSSFHDSVSK
HHCCCCCCCHHHHHH		28.7923749301
360UbiquitinationSFHDSVSKMYDWMDV
CCHHHHHHHHHHHHH		39.0517644757
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GPI3_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GPI3_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GPI3_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ERI1_YEASTERI1physical
15163411
VPS1_YEASTVPS1genetic
23891562
VPS8_YEASTVPS8genetic
23891562
VPS5_YEASTVPS5genetic
23891562
VPS17_YEASTVPS17genetic
23891562
VPS21_YEASTVPS21genetic
23891562
PACC_YEASTRIM101genetic
23891562
PALH_YEASTRIM21genetic
23891562
ELO3_YEASTELO3genetic
23891562
CSG2_YEASTCSG2genetic
23891562
RPN6_YEASTRPN6genetic
23891562
RPN5_YEASTRPN5genetic
23891562
PSB1_YEASTPRE3genetic
23891562
PSB5_YEASTPRE2genetic
23891562
YM122_YEASTYMR122W-Agenetic
27811238
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GPI3_YEAST

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Related Literatures of Post-Translational Modification

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