RTC5_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RTC5_YEAST
• UniProt AC: Q12108
• Protein Name: Restriction of telomere capping protein 5
• Gene Name: RTC5
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 567
• Subcellular Localization: Cytoplasm .
• Protein Description: May be involved in a process influencing telomere capping..
• Protein Sequence: MGQSSSISSSNEEGSSHSKKFTNSKDILAYFNNKAQQQVTIPELVSFKGNLQIEDLNTPISHKALCNSLYFPQNHAMIVGIVTNMLRVLSNFPLMKSSYEPITGYGLLKCILLLNRARCAKFLKTKSYDQLKLLFISLSLQKTDKEELSEESENDGNKELTIKQIITGFDDVDTEMLCIPADFMLQFLTWLLILTVDCPTTNSKLDNTETHDQWGNFKVSALNLLRTMNPDVVGDIESHSITFQQFSTAIRTVMPNLLKPLENLMEHFFYLQHDLVDHDTNLSSIQDSKVMTPALLAQLSTGLPKELFIHKLQSLYIGRKSGFSMRSLQAKVFKWMAPSILVVSGMRITNSEEYAAEKNPRYRHFLEEFPKLKESDQMMDASHLNKRKTTFAVYIDDPWKVTNKDYFGDLNTRIIEISPRQDIYKVNQKGTIYFNTIGGGIGIGDKQPLIKPASKRYIPGNVSLTFDSTLEFAVFRNTGYGGSLDPGLLSMERKEENSPYELHFLIQDVEVWGCGGEKELEEQIKQLEWEEAESKRRQQINLRSLGEDRALLEMAGLVGQHQGGGSM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MGQSSSISSSN ----CCCCCCCCCCC	21.96	30377154
5	Phosphorylation	---MGQSSSISSSNE ---CCCCCCCCCCCC	24.65	30377154
6	Phosphorylation	--MGQSSSISSSNEE --CCCCCCCCCCCCC	31.56	30377154
8	Phosphorylation	MGQSSSISSSNEEGS CCCCCCCCCCCCCCC	29.66	30377154
9	Phosphorylation	GQSSSISSSNEEGSS CCCCCCCCCCCCCCC	35.20	30377154
10	Phosphorylation	QSSSISSSNEEGSSH CCCCCCCCCCCCCCC	41.28	30377154
15	Phosphorylation	SSSNEEGSSHSKKFT CCCCCCCCCCCCCCC	28.32	30377154
16	Phosphorylation	SSNEEGSSHSKKFTN CCCCCCCCCCCCCCC	42.51	30377154
18	Phosphorylation	NEEGSSHSKKFTNSK CCCCCCCCCCCCCHH	39.22	30377154
149	Phosphorylation	KTDKEELSEESENDG CCCHHHHCHHHCCCC	42.47	30377154
152	Phosphorylation	KEELSEESENDGNKE HHHHCHHHCCCCCCE	37.33	30377154
358	Ubiquitination	SEEYAAEKNPRYRHF HHHHHHHHCHHHHHH	68.47	23749301
404	Acetylation	DPWKVTNKDYFGDLN CCCCCCCCHHCCCCC	44.43	24489116
566	Phosphorylation	GQHQGGGSM------ CCCCCCCCC------	25.29	22369663

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RTC5_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RTC5_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RTC5_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
IMG2_YEAST	IMG2	genetic	27708008
YD012_YEAST	YDL012C	genetic	27708008
MTU1_YEAST	SLM3	genetic	27708008
GPR1_YEAST	GPR1	genetic	27708008
RLA1_YEAST	RPP1A	genetic	27708008
YD179_YEAST	YDR179W-A	genetic	27708008
HUR1_YEAST	HUR1	genetic	27708008
YRA2_YEAST	YRA2	genetic	27708008
RL37A_YEAST	RPL37A	genetic	27708008
NST1_YEAST	NST1	genetic	27708008
ATG13_YEAST	ATG13	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.