dbPTM

SPO23_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SPO23_YEAST
UniProt AC	P33757
Protein Name	Sporulation protein 23
Gene Name	SPO23
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	523
Subcellular Localization
Protein Description	Regulates expression of PIS1..
Protein Sequence	MLFSSSSSSLNSEVSQVFSENISSRSTTLTESSTQSEIRQHFGNEDFSGELPKKLIQLKKLKNGGTTIKKAKEDLEYCYDSLRLYENPYVTSSVDKKCGYSIELYLDNKYKTLMFSDLQLNADYPLYYDSSLDNISTNVERERATPLQIKGKIRINIDREDQALLITSHSISLKCFTKEYACFVNSETSKNSYSDKIIKELNHTEFFESSTYPKQQLRVIHHSLNDKKILLTKGTYDYPFTFTLQANTFPASFSSFFGKTHFRIESLTTIMRIPSKPKNLLKFLKNESFTDKIILTEEIKVKRVLPSTSMLKFETFQLRSYNTASEIVVSVIGNSKLIEIGMPFQMILSITKTDSSIELQEASLAVAQRMAIPSIDLKTKKILREPYIKKSEYLLRTVESQSFDSDKTIFGFCFDDVVIPTYADGLPSWFKTFYCEPSSFYPNHAALKVTHLLLFRITYSRNELVEGLEMKKNYRITVNFPILVGDSDISTSSLLPKYEKFENISDLQDEPPLYSMVAGENSL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
67	Phosphorylation	KLKNGGTTIKKAKED ECCCCCCCCHHHHHH	33.79	28889911
85	Phosphorylation	CYDSLRLYENPYVTS HHHHHHHCCCCCCCC	13.76	28889911
89	Phosphorylation	LRLYENPYVTSSVDK HHHCCCCCCCCCCCC	28.13	28889911
92	Phosphorylation	YENPYVTSSVDKKCG CCCCCCCCCCCCCCC	20.51	28889911
93	Phosphorylation	ENPYVTSSVDKKCGY CCCCCCCCCCCCCCE	25.60	28889911
355	Phosphorylation	LSITKTDSSIELQEA EEEECCCCCHHHHHH	38.15	25882841
363	Phosphorylation	SIELQEASLAVAQRM CHHHHHHHHHHHHHH	18.99	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SPO23_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SPO23_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SPO23_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SPO74_YEAST	SPO74	genetic	27708008
MED20_YEAST	SRB2	genetic	27708008
MKT1_YEAST	MKT1	genetic	27708008
NCBP2_YEAST	CBC2	genetic	27708008
SGF29_YEAST	SGF29	genetic	27708008
YD012_YEAST	YDL012C	genetic	27708008
UBP3_YEAST	UBP3	genetic	27708008
VPS29_YEAST	VPS29	genetic	27708008
SDHX_YEAST	YJL045W	genetic	27708008
RSSA2_YEAST	RPS0B	genetic	27708008
SWI6_YEAST	SWI6	genetic	27708008
SST2_YEAST	SST2	genetic	27708008
PFKA2_YEAST	PFK2	genetic	27708008
YNB0_YEAST	YNL010W	genetic	27708008
MKS1_YEAST	MKS1	genetic	27708008
ADE_YEAST	AAH1	genetic	27708008
RTG1_YEAST	RTG1	genetic	27708008
RS10A_YEAST	RPS10A	genetic	27708008
PMA2_YEAST	PMA2	genetic	27708008
H1_YEAST	HHO1	genetic	27708008
KAR3_YEAST	KAR3	genetic	27708008
TFC3_YEAST	TFC3	genetic	29674565
SMT3_YEAST	SMT3	genetic	29674565
RRM3_YEAST	RRM3	genetic	29674565
NSE5_YEAST	NSE5	genetic	29674565
NAM7_YEAST	NAM7	genetic	29674565
CSG2_YEAST	CSG2	genetic	29674565
ALG14_YEAST	ALG14	genetic	29674565
NKP1_YEAST	NKP1	genetic	29674565
CSF1_YEAST	CSF1	genetic	29674565
SIN3_YEAST	SIN3	genetic	29674565
HSP7F_YEAST	SSE1	genetic	29674565
HSP26_YEAST	HSP26	genetic	29674565
CLG1_YEAST	CLG1	genetic	29674565
STS1_YEAST	STS1	genetic	29674565
ATP18_YEAST	ATP18	genetic	29674565

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SPO23_YEAST

Related Literatures of Post-Translational Modification