MDL1_YEAST - dbPTM
MDL1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MDL1_YEAST
UniProt AC P33310
Protein Name ATP-dependent permease MDL1, mitochondrial
Gene Name MDL1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 695
Subcellular Localization Mitochondrion inner membrane
Multi-pass membrane protein .
Protein Description Mediates export of peptides with molecular masses of 2100 to 600 daltons generated upon proteolysis of mitochondrial inner membrane proteins..
Protein Sequence MIVRMIRLCKGPKLLRSQFASASALYSTKSLFKPPMYQKAEINLIIPHRKHFLLRSIRLQSDIAQGKKSTKPTLKLSNANSKSSGFKDIKRLFVLSKPESKYIGLALLLILISSSVSMAVPSVIGKLLDLASESDGEDEEGSKSNKLYGFTKKQFFTALGAVFIIGAVANASRIIILKVTGERLVARLRTRTMKAALDQDATFLDTNRVGDLISRLSSDASIVAKSVTQNVSDGTRAIIQGFVGFGMMSFLSWKLTCVMMILAPPLGAMALIYGRKIRNLSRQLQTSVGGLTKVAEEQLNATRTIQAYGGEKNEVRRYAKEVRNVFHIGLKEAVTSGLFFGSTGLVGNTAMLSLLLVGTSMIQSGSMTVGELSSFMMYAVYTGSSLFGLSSFYSELMKGAGAAARVFELNDRKPLIRPTIGKDPVSLAQKPIVFKNVSFTYPTRPKHQIFKDLNITIKPGEHVCAVGPSGSGKSTIASLLLRYYDVNSGSIEFGDEDIRNFNLRKYRRLIGYVQQEPLLFNGTILDNILYCIPPEIAEQDDRIRRAIGKANCTKFLANFPDGLQTMVGARGAQLSGGQKQRIALARAFLLDPAVLILDEATSALDSQSEEIVAKNLQRRVERGFTTISIAHRLSTIKHSTRVIVLGKHGSVVETGSFRDLIAIPNSELNALLAEQQDEEGKGGVIDLDNSVAREV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
134PhosphorylationLLDLASESDGEDEEG
HHHHHHCCCCCCCCC		48.7128889911
142PhosphorylationDGEDEEGSKSNKLYG
CCCCCCCCCCCCCCC		35.8728889911
144PhosphorylationEDEEGSKSNKLYGFT
CCCCCCCCCCCCCCC		40.6828889911
304PhosphorylationEQLNATRTIQAYGGE
HHHHCCCHHHHCCCC		17.0627017623
308PhosphorylationATRTIQAYGGEKNEV
CCCHHHHCCCCHHHH		14.8627017623
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MDL1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MDL1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MDL1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GTS1_YEASTGTS1physical
9914482
MDL1_YEASTMDL1physical
12746444
MDL1_YEASTMDL1physical
16352609
MDL1_YEASTMDL1physical
17892490
SSK22_YEASTSSK22genetic
20093466
YD180_YEASTYDL180Wgenetic
20093466
ENT1_YEASTENT1genetic
20093466
CRD1_YEASTCRD1genetic
20093466
PRM7_YEASTPRM7genetic
20093466
MTU1_YEASTSLM3genetic
20093466
DPP1_YEASTDPP1genetic
20093466
IRC3_YEASTIRC3genetic
20093466
SHE9_YEASTSHE9genetic
20093466
CYM1_YEASTCYM1genetic
20093466
EMI1_YEASTEMI1genetic
20093466
AGE1_YEASTAGE1genetic
20093466
CEM1_YEASTCEM1genetic
20093466
ICP55_YEASTICP55genetic
20093466
TAPT1_YEASTEMP65genetic
20093466
YGY5_YEASTYGL235Wgenetic
20093466
CLG1_YEASTCLG1genetic
20093466
YG1O_YEASTYGR035Cgenetic
20093466
DBF2_YEASTDBF2genetic
20093466
PHB1_YEASTPHB1genetic
20093466
PBP1_YEASTPBP1genetic
20093466
XKS1_YEASTXKS1genetic
20093466
PSD10_YEASTNAS6genetic
20093466
SNF6_YEASTSNF6genetic
20093466
HSE1_YEASTHSE1genetic
20093466
MED20_YEASTSRB2genetic
20093466
LRP1_YEASTLRP1genetic
20093466
OYE2_YEASTOYE2genetic
20093466
NACA_YEASTEGD2genetic
20093466
AMYG_YEASTSGA1genetic
20093466
SDS3_YEASTSDS3genetic
20093466
SPO22_YEASTSPO22genetic
20093466
FIS1_YEASTFIS1genetic
20093466
EFM4_YEASTEFM4genetic
20093466
YIC9_YEASTYIL029Cgenetic
20093466
MRX5_YEASTYJL147Cgenetic
20093466
CYP7_YEASTCPR7genetic
20093466
SAC1_YEASTSAC1genetic
20093466
FRMSR_YEASTYKL069Wgenetic
20093466
RL14A_YEASTRPL14Agenetic
20093466
RS21A_YEASTRPS21Agenetic
20093466
FRA1_YEASTFRA1genetic
20093466
COX12_YEASTCOX12genetic
20093466
COQ11_YEASTYLR290Cgenetic
20093466
YL345_YEASTYLR345Wgenetic
20093466
MSC1_YEASTMSC1genetic
20093466
TSL1_YEASTTSL1genetic
20093466
RCF1_YEASTRCF1genetic
20093466
RIM13_YEASTRIM13genetic
20093466
TPP1_YEASTTPP1genetic
20093466
YM39_YEASTYMR166Cgenetic
20093466
MKK1_YEASTMKK1genetic
20093466
RDL1_YEASTRDL1genetic
20093466
GIP3_YEASTGIP3genetic
20093466
LEE1_YEASTLEE1genetic
20093466
EAF3_YEASTEAF3genetic
20093466
UBA3_YEASTUBA3genetic
20093466
ATG13_YEASTATG13genetic
20093466
QCR2_YEASTQCR2genetic
20093466
CYM1_YEASTCYM1genetic
21987634
THDH_YEASTILV1genetic
21987634
PHB1_YEASTPHB1genetic
21987634
PHB2_YEASTPHB2genetic
21987634
ATP12_YEASTATP12genetic
21987634
IPYR2_YEASTPPA2genetic
21987634
GEP3_YEASTGEP3genetic
21987634
YME1_YEASTYME1genetic
21987634
MKK1_YEASTMKK1genetic
22282571
MED20_YEASTSRB2genetic
27708008
CYP7_YEASTCPR7genetic
27708008
ARL1_YEASTARL1genetic
27708008
RV161_YEASTRVS161genetic
27708008
RIM1_YEASTRIM1genetic
27708008
SSK22_YEASTSSK22genetic
27708008
GPR1_YEASTGPR1genetic
27708008
VAM6_YEASTVAM6genetic
27708008
NUP59_YEASTASM4genetic
27708008
CRD1_YEASTCRD1genetic
27708008
YD180_YEASTYDL180Wgenetic
27708008
NUP42_YEASTNUP42genetic
27708008
SHE9_YEASTSHE9genetic
27708008
CYM1_YEASTCYM1genetic
27708008
AGE1_YEASTAGE1genetic
27708008
CEM1_YEASTCEM1genetic
27708008
ICP55_YEASTICP55genetic
27708008
UBP3_YEASTUBP3genetic
27708008
MRM2_YEASTMRM2genetic
27708008
CLG1_YEASTCLG1genetic
27708008
YG1O_YEASTYGR035Cgenetic
27708008
PBP1_YEASTPBP1genetic
27708008
PSD10_YEASTNAS6genetic
27708008
SCW4_YEASTSCW4genetic
27708008
SNF6_YEASTSNF6genetic
27708008
SSBP1_YEASTSBP1genetic
27708008
FMO1_YEASTFMO1genetic
27708008
OYE2_YEASTOYE2genetic
27708008
PTH_YEASTPTH1genetic
27708008
YIC9_YEASTYIL029Cgenetic
27708008
YIF4_YEASTYIL054Wgenetic
27708008
SPO22_YEASTSPO22genetic
27708008
YJV3_YEASTYJL213Wgenetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
CBT1_YEASTCBT1genetic
27708008
SAC1_YEASTSAC1genetic
27708008
RS21A_YEASTRPS21Agenetic
27708008
FRA1_YEASTFRA1genetic
27708008
COQ11_YEASTYLR290Cgenetic
27708008
YL345_YEASTYLR345Wgenetic
27708008
RCF1_YEASTRCF1genetic
27708008
TSL1_YEASTTSL1genetic
27708008
MSC1_YEASTMSC1genetic
27708008
MAC1_YEASTMAC1genetic
27708008
RIM13_YEASTRIM13genetic
27708008
TPP1_YEASTTPP1genetic
27708008
YM39_YEASTYMR166Cgenetic
27708008
COQ7_YEASTCAT5genetic
27708008
RGA1_YEASTRGA1genetic
27708008
MKK1_YEASTMKK1genetic
27708008
LEE1_YEASTLEE1genetic
27708008
MDL2_YEASTMDL2genetic
27708008
EAF3_YEASTEAF3genetic
27708008
UBA3_YEASTUBA3genetic
27708008
ATG13_YEASTATG13genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MDL1_YEAST

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Related Literatures of Post-Translational Modification

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