AGE1_YEAST - dbPTM
AGE1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID AGE1_YEAST
UniProt AC Q04412
Protein Name ADP-ribosylation factor GTPase-activating protein effector protein 1
Gene Name AGE1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 482
Subcellular Localization Cytoplasm .
Protein Description GTPase-activating protein (GAP) for the ADP ribosylation factors ARF1 and ARF2. May be involved in the endocytic pathway..
Protein Sequence MDFYTTDINKNVVPLFSKGTVARTASKAQYPSWCNNALKLTNILLKSLRCKFQTNRCEDDRGFEVYCVILKSIALLMAAKESLILLQIPPSLPSGFPFRSPQLSFTYLSTRLSGSQHKSTHSHHINHQTHPIHSSSSNSNSNNRIPTKTDSSKQHTQHFSFANAGASNRDELLSIVRKIDKSNLKCCDCGSTATVEWVSINLLCILCIKCSGVHRSLGSHISKIRSLTLDNFTSLELMHLLQNNVSNSNVNAIYESNLRNFPVKKITANSDDSERSKFIIDKYQFKKFVIDSNQGREASLKSLIKAIHLDSVFMMQRAIAQSKYSLRELTASEKEQNDLNHSSIFQYSLKHYEIVDGTPIFFITEFLLCNGIHIDNLPKITTNWSPKVLEYWETKLEMYGTFQAVNTSRPRSGPHLNMHSNVDSASSYNKKHDLRVNIPERSASASKRWSLSSIPKSSQNLMSPTNLLTMHKSLKLAKKDKK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
100PhosphorylationPSGFPFRSPQLSFTY
CCCCCCCCCCEEEEE		19.8521126336
119PhosphorylationLSGSQHKSTHSHHIN
CCCCCCCCCCCCCCC		29.2727017623
135PhosphorylationQTHPIHSSSSNSNSN
CCCCCCCCCCCCCCC		24.5127017623
147PhosphorylationNSNNRIPTKTDSSKQ
CCCCCCCCCCCCCHH		44.1830377154
149PhosphorylationNNRIPTKTDSSKQHT
CCCCCCCCCCCHHHH		43.5230377154
151PhosphorylationRIPTKTDSSKQHTQH
CCCCCCCCCHHHHHE		44.6730377154
152PhosphorylationIPTKTDSSKQHTQHF
CCCCCCCCHHHHHEE		38.8630377154
267PhosphorylationNFPVKKITANSDDSE
CCCEEEEECCCCCCH		28.7628889911
273PhosphorylationITANSDDSERSKFII
EECCCCCCHHHCEEE		39.6428889911
412PhosphorylationVNTSRPRSGPHLNMH
CCCCCCCCCCCCCCC		60.4027017623
424PhosphorylationNMHSNVDSASSYNKK
CCCCCCCCCHHCCCC		26.2627017623
442PhosphorylationRVNIPERSASASKRW
ECCCCCCCCCCHHCC		25.5524961812
444PhosphorylationNIPERSASASKRWSL
CCCCCCCCCHHCCCH		34.0324961812
446PhosphorylationPERSASASKRWSLSS
CCCCCCCHHCCCHHH		21.9124961812
450PhosphorylationASASKRWSLSSIPKS
CCCHHCCCHHHCCHH		23.5421440633
452PhosphorylationASKRWSLSSIPKSSQ
CHHCCCHHHCCHHHC		22.2421440633
453PhosphorylationSKRWSLSSIPKSSQN
HHCCCHHHCCHHHCC		48.4821440633
458PhosphorylationLSSIPKSSQNLMSPT
HHHCCHHHCCCCCHH		29.2521440633
463PhosphorylationKSSQNLMSPTNLLTM
HHHCCCCCHHHHHHH		31.5729136822
465PhosphorylationSQNLMSPTNLLTMHK
HCCCCCHHHHHHHHH		31.0621551504
469PhosphorylationMSPTNLLTMHKSLKL
CCHHHHHHHHHHHHH		22.0129136822
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of AGE1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of AGE1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of AGE1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GLO3_YEASTGLO3genetic
12627398
SCS7_YEASTSCS7genetic
16269340
RIC1_YEASTRIC1genetic
16269340
SWA2_YEASTSWA2genetic
16269340
ERG4_YEASTERG4genetic
16269340
SHR3_YEASTSHR3genetic
16269340
AGE2_YEASTAGE2genetic
12627398
SPO14_YEASTSPO14genetic
21135091
BUD31_YEASTBUD31genetic
27708008
VRP1_YEASTVRP1genetic
27708008
RCR1_YEASTRCR1genetic
27708008
RV161_YEASTRVS161genetic
27708008
YD121_YEASTYDL121Cgenetic
27708008
PMP3_YEASTPMP3genetic
27708008
PIB2_YEASTPIB2genetic
27708008
BGL2_YEASTBGL2genetic
27708008
VPS53_YEASTVPS53genetic
27708008
ELM1_YEASTELM1genetic
27708008
SST2_YEASTSST2genetic
27708008
SCS7_YEASTSCS7genetic
27708008
FKBP_YEASTFPR1genetic
27708008
YNO0_YEASTYNL140Cgenetic
27708008
PFD4_YEASTGIM3genetic
27708008
MSO1_YEASTMSO1genetic
27708008
BRE5_YEASTBRE5genetic
27708008
PHO80_YEASTPHO80genetic
27708008
ALDH6_YEASTALD6genetic
27708008
GGPPS_YEASTBTS1genetic
27708008
NEW1_YEASTNEW1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of AGE1_YEAST

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