dbPTM

SPO22_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SPO22_YEAST
UniProt AC	P40511
Protein Name	Sporulation-specific protein 22
Gene Name	SPO22
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	975
Subcellular Localization
Protein Description	Involved in chromosome segregation during sporulation..
Protein Sequence	MSDHNVNSTFRKTLVELCETATWITSQVYAAKNLEKNDLITVDNKISALYPIAEKYDRSFRTTTVILDEELILKLENAASSLWNSLTIAMKAEKASDKYFNEVFCKCKIFATKLLSIHEALFRTNTNLLRNFKCYISSFKSASEYRFDDLITNTQQHSEKYLQIINENVESFSNEEKTEFKKLTFEFYLVNFQLYLSENDLDTANIYTAKVNITDNSKYMDADLLIELCRMIYNSTVMLKEINNPETQLVDVNIISFLKDVEKYLELPVENLKSHTDYSNLKYSVLIFMANCLVEGHPQASELEQCDHYLSLLQNEYPNKVDPFILAINLTKRRNIVNPAETIEEILMRMIMSVDVISNFQAVIASINDLSKMNTKFSIVCLDYLLINKLNSKNDSKFLGKAICSRFLITTQSKTMNDSEIAESLENFSTQMERIVSEPLTKHAISCIITLLWNTGKKLEKMEKYVVSIRFYKLALKDIISQNYSDRGKIQRALQVVYNKIEDYSNTVRVYQDMDEVDRQSPLCQLLMLQSFLADDKTEEALTCLQKIKSSEDEKSTDALILAVAECKRKTDLSVQGLLMIFDKLQSKSNSQTISSTSSSQTLSILRYTLQMIVKVSEEEPLETFINYLPTVQKLLQKAVEFLKTVKLLNQLPPDVEKEAIYQQSVAVNEIEWFASFSYNVAVKCLVDQSCESISEFPQYCIQFIDLIPVQDFTFPKMYHFTYWRFKATILQLIIAKEKAKQDQHQKDWDIYEKSEELVNSINVMKKSSEFKDGSSLEDRNTLHECFLEALTIHLESALMMPDQTRILDILKKTELYQDSRVDALLIDISSNMEDLPKGVLIEILETVLKRNMGPEVKERELCSWLRILLENAINLNHEVELRILDRVLKILNINQSSLQDTDGVLQTELETIATYCWNIGVNYIIKDNKSNGIVWCKHSMGFANMVNEGLQEQLYSLWESLASSANIDINSIAK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
608	Phosphorylation	QTLSILRYTLQMIVK HHHHHHHHHHHHHCC	14.35	28132839
817	Phosphorylation	ILKKTELYQDSRVDA HHHHCCHHCCCCCCE	12.21	19779198
820	Phosphorylation	KTELYQDSRVDALLI HCCHHCCCCCCEEEE	20.76	19779198
830	Phosphorylation	DALLIDISSNMEDLP CEEEEECCCCCCCCC	16.35	19779198
864	Phosphorylation	VKERELCSWLRILLE HHHHHHHHHHHHHHH	41.59	27017623

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SPO22_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SPO22_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SPO22_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SPO16_YEAST	SPO16	physical	18297071
RL19A_YEAST	RPL19B	genetic	27708008
RL19B_YEAST	RPL19B	genetic	27708008
BUD31_YEAST	BUD31	genetic	27708008
BUL2_YEAST	BUL2	genetic	27708008
RTG1_YEAST	RTG1	genetic	27708008
ERV46_YEAST	ERV46	genetic	27708008
YAJ9_YEAST	YAR029W	genetic	27708008
SWC5_YEAST	SWC5	genetic	27708008
GPR1_YEAST	GPR1	genetic	27708008
YD180_YEAST	YDL180W	genetic	27708008
BLM10_YEAST	BLM10	genetic	27708008
RIM15_YEAST	RIM15	genetic	27708008
SPO74_YEAST	SPO74	genetic	27708008
ARO8_YEAST	ARO8	genetic	27708008
CUL3_YEAST	CUL3	genetic	27708008
MAL12_YEAST	MAL12	genetic	27708008
PRY1_YEAST	PRY1	genetic	27708008
SET2_YEAST	SET2	genetic	27708008
YL053_YEAST	YLR053C	genetic	27708008
YL287_YEAST	YLR287C	genetic	27708008
ATG39_YEAST	YLR312C	genetic	27708008
PUN1_YEAST	PUN1	genetic	27708008
RL6B_YEAST	RPL6B	genetic	27708008
GIS4_YEAST	GIS4	genetic	27708008
HMDH1_YEAST	HMG1	genetic	27708008
PO152_YEAST	POM152	genetic	27708008
HDA1_YEAST	HDA1	genetic	27708008
COX5A_YEAST	COX5A	genetic	27708008
YNL5_YEAST	YNL115C	genetic	27708008
INO4_YEAST	INO4	genetic	27708008
YGK3_YEAST	YGK3	genetic	27708008
CSK2C_YEAST	CKB2	genetic	27708008
ATX2_YEAST	ATX2	genetic	27708008
KIN4_YEAST	KIN4	genetic	27708008
RDL1_YEAST	RDL1	genetic	27708008
RL21B_YEAST	RPL21B	genetic	27708008
NAA30_YEAST	MAK3	genetic	27708008
MDM36_YEAST	MDM36	genetic	27708008
ZIP1_YEAST	ZIP1	genetic	27913618
MLH2_YEAST	MLH2	genetic	28051769
HFM1_YEAST	HFM1	genetic	28051769

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SPO22_YEAST

Related Literatures of Post-Translational Modification