| UniProt ID | POS5_YEAST | |
|---|---|---|
| UniProt AC | Q06892 | |
| Protein Name | NADH kinase POS5, mitochondrial | |
| Gene Name | POS5 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 414 | |
| Subcellular Localization | Mitochondrion matrix . | |
| Protein Description | Phosphorylates both NADH and NAD(+), with a twofold preference for NADH. Anti-oxidant factor and key source of the cellular reductant NADPH.. | |
| Protein Sequence | MFVRVKLNKPVKWYRFYSTLDSHSLKLQSGSKFVKIKPVNNLRSSSSADFVSPPNSKLQSLIWQNPLQNVYITKKPWTPSTREAMVEFITHLHESYPEVNVIVQPDVAEEISQDFKSPLENDPNRPHILYTGPEQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKVFQEVISSRAKCLHRTRLECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVALATPTGSTAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIKIGSKLNQKPVNSVVKLSVDGIPQQDLDVGDEIYVINEVGTIYIDGTQLPTTRKTENDFNNSKKPKRSGIYCVAKTENDWIRGINELLGFNSSFRLTKRQTDND | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 32 | Acetylation | LKLQSGSKFVKIKPV EEECCCCEEEEEEEC | 58.67 | 24489116 | |
| 35 | Acetylation | QSGSKFVKIKPVNNL CCCCEEEEEEECCCC | 48.41 | 24489116 | |
| 44 | Phosphorylation | KPVNNLRSSSSADFV EECCCCCCCCCCCCC | 37.42 | 24930733 | |
| 45 | Phosphorylation | PVNNLRSSSSADFVS ECCCCCCCCCCCCCC | 23.13 | 24930733 | |
| 216 | Phosphorylation | CHLKKKDSNSSIVTH EEEECCCCCCCHHHH | 47.71 | 27017623 | |
| 219 | Phosphorylation | KKKDSNSSIVTHAMN ECCCCCCCHHHHHHH | 25.90 | 27017623 | |
| 222 | Phosphorylation | DSNSSIVTHAMNDIF CCCCCHHHHHHHHHH | 11.40 | 27017623 | |
| 381 | Phosphorylation | KPKRSGIYCVAKTEN CCCCCCEEEEEECCC | 5.61 | 27017623 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of POS5_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of POS5_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of POS5_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| COQ1_YEAST | COQ1 | genetic | 12727869 | |
| UTR1_YEAST | UTR1 | genetic | 15978040 | |
| YEF1_YEAST | YEF1 | genetic | 15978040 | |
| UTR1_YEAST | UTR1 | genetic | 16760478 | |
| UTR1_YEAST | UTR1 | genetic | 16680368 | |
| YEF1_YEAST | YEF1 | genetic | 16680368 | |
| YEF1_YEAST | YEF1 | genetic | 19158096 | |
| MAOM_YEAST | MAE1 | genetic | 19158096 | |
| ALDH4_YEAST | ALD4 | genetic | 19158096 | |
| ALDH5_YEAST | ALD5 | genetic | 19158096 | |
| IDHP_YEAST | IDP1 | genetic | 22011405 | |
| BANP_HUMAN | BANP | physical | 27107014 | |
| NADK_HUMAN | NADK | physical | 27107014 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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