COQ1_YEAST - dbPTM
COQ1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID COQ1_YEAST
UniProt AC P18900
Protein Name Hexaprenyl pyrophosphate synthase, mitochondrial
Gene Name COQ1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 473
Subcellular Localization Mitochondrion inner membrane
Peripheral membrane protein
Matrix side.
Protein Description Assembly of polyisoprenoid side chains. The polyprenyl synthase of coenzyme Q biosynthesis catalyzes the formation from isopentenyl diphosphate of all trans-polyprenyl pyrophosphates generally ranging in length of between 6 and 10 isoprene units depending on the species..
Protein Sequence MFQRSGAAHHIKLISSRRCRFKSSFAVALNAASKLVTPKILWNNPISLVSKEMNTLAKNIVALIGSGHPVLNKVTSYYFETEGKKVRPLLVLLLSRALSEIPMTERNHLKIDKSDVPEDPIYSKPSQNQLFQRPASSISPLHILHGIKPLNPLTKGPEPLPEETFDKQRGILPKQRRLAEIVEMIHTASLLHDDVIDHSDTRRGRPSGNAAFTNKMAVLAGDFLLGRATVSISRLHNPEVVELMSNSIANLVEGEFMQLKNTSIDADIDTIENGHKLLPVPSKKLEVKEHDFRVPSRQQGLQLSHDQIIETAFEYYIHKTYLKTAALISKSCRCAAILSGASPAVIDECYDFGRNLGICFQLVDDMLDFTVSGKDLGKPSGADLKLGIATAPVLFAWKEDPSLGPLISRNFSERGDVEKTIDSVRLHNGIAKTKILAEEYRDKALQNLRDSLPESDARSALEFLTNSILTRRK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
23PhosphorylationSRRCRFKSSFAVALN
CCCCCCCHHHHHHHH		28.1619823750
24PhosphorylationRRCRFKSSFAVALNA
CCCCCCHHHHHHHHH		20.1619823750
33PhosphorylationAVALNAASKLVTPKI
HHHHHHHHHCCCCHH		24.9019823750
167AcetylationLPEETFDKQRGILPK
CCHHHHHHHCCCCHH		37.3924489116
263PhosphorylationFMQLKNTSIDADIDT
CCCCCCCCCCCCHHH		28.0620377248
320PhosphorylationFEYYIHKTYLKTAAL
HHHHHHHHHHHHHHH		21.6627017623
321PhosphorylationEYYIHKTYLKTAALI
HHHHHHHHHHHHHHH		15.8227017623
324PhosphorylationIHKTYLKTAALISKS
HHHHHHHHHHHHCHH		17.9927017623
329PhosphorylationLKTAALISKSCRCAA
HHHHHHHCHHCHHHH		21.2627017623
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of COQ1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of COQ1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of COQ1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
DPS1_SCHPOdps1physical
18540885
EXO84_YEASTEXO84genetic
27708008
RCC1_YEASTSRM1genetic
27708008
EXO70_YEASTEXO70genetic
27708008
ALG1_YEASTALG1genetic
27708008
POP7_YEASTPOP7genetic
27708008
MPS1_YEASTMPS1genetic
27708008
TIM22_YEASTTIM22genetic
27708008
SLU7_YEASTSLU7genetic
27708008
TFB1_YEASTTFB1genetic
27708008
RSP5_YEASTRSP5genetic
27708008
MOB2_YEASTMOB2genetic
27708008
ACT_YEASTACT1genetic
27708008
STT3_YEASTSTT3genetic
27708008
MED6_YEASTMED6genetic
27708008
ATC7_YEASTNEO1genetic
27708008
SLN1_YEASTSLN1genetic
27708008
PAN1_YEASTPAN1genetic
27708008
TIM16_YEASTPAM16genetic
27708008
BOS1_YEASTBOS1genetic
27708008
CDC45_YEASTCDC45genetic
27708008
RU1C_YEASTYHC1genetic
27708008
TAF13_YEASTTAF13genetic
27708008
MCM1_YEASTMCM1genetic
27708008
CAP_YEASTSRV2genetic
27708008
TFC8_YEASTTFC8genetic
27708008
COPZ_YEASTRET3genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of COQ1_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory