| UniProt ID | COQ5_YEAST | |
|---|---|---|
| UniProt AC | P49017 | |
| Protein Name | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03191, ECO:0000303|PubMed:9083049} | |
| Gene Name | COQ5 {ECO:0000255|HAMAP-Rule:MF_03191, ECO:0000303|PubMed:9083048, ECO:0000303|PubMed:9083049} | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 307 | |
| Subcellular Localization |
Mitochondrion inner membrane Peripheral membrane protein Matrix side . |
|
| Protein Description | Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).. | |
| Protein Sequence | MLISSRIVRSSLVNVPLRLSRCFTQAHRACKEEEVNSPLSSAAEQPEQKYTHFGSKTVLKSTKQKLVGDVFSSVANRYDLMNDVMSLGIHRLWKDHFINKLDAGKRPNSTTPLNFIDVAGGSGDIAFGLLDHAESKFGDTESTMDIVDINPDMLKEGEKRAMEQGKYFKDPRVRFLVSNGEKLEEIDSDSKDIYTVSFGIRNFTDIQKGLNTAYRVLKPGGIFYCLEFSKIENPLMDFAYQQWAKVLPVMGSMIANDYDSYQYLVESIERFPDQETFKSMIEKAGFKSAGYESLTFGICAIHWGIKV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 37 | Phosphorylation | CKEEEVNSPLSSAAE HCHHHCCCCCCHHHC | 32.18 | 29136822 | |
| 40 | Phosphorylation | EEVNSPLSSAAEQPE HHCCCCCCHHHCCCC | 22.70 | 29136822 | |
| 41 | Phosphorylation | EVNSPLSSAAEQPEQ HCCCCCCHHHCCCCH | 38.90 | 29136822 | |
| 55 | Phosphorylation | QKYTHFGSKTVLKST HHCCCCCCHHHHHHH | 24.98 | 25882841 | |
| 56 | Acetylation | KYTHFGSKTVLKSTK HCCCCCCHHHHHHHC | 42.93 | 24489116 | |
| 94 | Acetylation | LGIHRLWKDHFINKL HCHHHHHHHHHHHHC | 46.01 | 24489116 | |
| 182 | Acetylation | FLVSNGEKLEEIDSD EEEECCCCCEEECCC | 63.70 | 24489116 | |
| 208 | Acetylation | RNFTDIQKGLNTAYR CCHHHHHHHHHHHHH | 66.74 | 24489116 | |
| 283 | Acetylation | TFKSMIEKAGFKSAG HHHHHHHHHCCCCCC | 42.77 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of COQ5_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of COQ5_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of COQ5_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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