GPG1_YEAST - dbPTM
GPG1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GPG1_YEAST
UniProt AC P53130
Protein Name Heterotrimeric G protein gamma subunit GPG1
Gene Name GPG1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 126
Subcellular Localization Cytoplasm .
Protein Description Gamma subunit of a guanine nucleotide-binding protein (G protein). G proteins are involved as modulators or transducers in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Involved in the determination of the cAMP level according to nutritional conditions, most probably as a regulator of cAMP phosphodiesterase. Required for the control of pseudohyphal and haploid invasive growth..
Protein Sequence MFYLSDIEEEASAGAEPTYNFWEVLLFSNTQENLVTVVGELHTLTDRVVHYKIEPESREVTATTLPSLLALLLEKRNQARRLYRDVLSMKMSELDWDIDDLFTQLQEELTRTDDTLSMYPRRRFYH
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
115PhosphorylationELTRTDDTLSMYPRR
HHHCCCCCCCCCCCC
24.4427017623
119PhosphorylationTDDTLSMYPRRRFYH
CCCCCCCCCCCCCCC
7.1028889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GPG1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GPG1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GPG1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GPB2_YEASTGPB2physical
12150916
GUP1_YEASTGUP1genetic
20526336
RNQ1_YEASTRNQ1genetic
22529103
SAC3_YEASTSAC3genetic
27708008
XRS2_YEASTXRS2genetic
27708008
RV167_YEASTRVS167genetic
27708008
STP1_YEASTSTP1genetic
27708008
CAJ1_YEASTCAJ1genetic
27708008
SWP82_YEASTSWP82genetic
27708008
AIM18_YEASTAIM18genetic
27708008
SDHX_YEASTYJL045Wgenetic
27708008
JJJ2_YEASTJJJ2genetic
27708008
HAL5_YEASTHAL5genetic
27708008
ELF1_YEASTELF1genetic
27708008
PSR1_YEASTPSR1genetic
27708008
SRN2_YEASTSRN2genetic
27708008
COA4_YEASTCOA4genetic
27708008
CHS5_YEASTCHS5genetic
27708008
COX7_YEASTCOX7genetic
27708008
COG6_YEASTCOG6genetic
27708008
SWS2_YEASTSWS2genetic
27708008
BRE5_YEASTBRE5genetic
27708008
MDM12_YEASTMDM12genetic
27708008
TAT2_YEASTTAT2genetic
27708008
YO114_YEASTYOL114Cgenetic
27708008
SERC_YEASTSER1genetic
27708008
MNE1_YEASTMNE1genetic
27708008
TBP6_YEASTYTA6genetic
27708008
BECN1_YEASTVPS30genetic
27708008
RTC6_YEASTRTC6genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GPG1_YEAST

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Related Literatures of Post-Translational Modification

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