SLI1_YEAST - dbPTM
SLI1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SLI1_YEAST
UniProt AC P53304
Protein Name N-acetyltransferase SLI1
Gene Name SLI1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 468
Subcellular Localization Endoplasmic reticulum .
Protein Description Confers resistance to the sphingolipid biosynthesis inhibitor drug myriocin (ISP-1). Inactivates ISP-1 by converting it into N-acetyl-myriocin. Cooperates with YPK1 in mediating resistance to myriocin..
Protein Sequence MNLKLSAIESYFFHRSRLNLHSCFYVGIKLNELPKKSQLIAALKYTVIQHERLTCNVFYDELKKENFLQNILEPLKFCDLVEYRHDWDQLGETEINHIFQRYNFSYNENKPLWKILILPNQNQMLLLTDHVLMDGMSAIHVWETFMEGLQMQQPVEIDETIYSPSLNSSTEKIMSAPLYGDWPIPWNWHIVRQLVSRLHYWFPQTVVKNNRNLIQFANYSFPKDLLDDKPSDGTQKYKVKNTNHQWEFRLSPTHLNDILQECKANNTSLTSLLGALVCTSFEKIAAHEYTGSFLKIELPMNIRKPFERVLKLPSDDKLAVGNFIAVIEFNHKLHQNRGIWDIASQIQRAIRSSSEDKIIDKVNEVKLLEVISSQQYIEDKISLNNGPSSTFEVTNLGFQTFKDACNTSLPFYIVDATFNEPQGISSIFSLSVISTPGNGLHCCISYPNTLTKVLEPHWQYMKDYLNLY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
102PhosphorylationINHIFQRYNFSYNEN
HHHHHHHCCCCCCCC
15.1329734811
229UbiquitinationPKDLLDDKPSDGTQK
CHHHCCCCCCCCCEE
46.1923749301

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SLI1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SLI1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SLI1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
UAP1_YEASTQRI1genetic
27708008
GLE1_YEASTGLE1genetic
27708008
DBF4_YEASTDBF4genetic
27708008
MAK21_YEASTMAK21genetic
27708008
SNU56_YEASTSNU56genetic
27708008
MOB2_YEASTMOB2genetic
27708008
ATC7_YEASTNEO1genetic
27708008
KRE9_YEASTKRE9genetic
27708008
CDC11_YEASTCDC11genetic
27708008
UGPA1_YEASTUGP1genetic
27708008
PRI2_YEASTPRI2genetic
27708008
PRP19_YEASTPRP19genetic
27708008
RU1C_YEASTYHC1genetic
27708008
TAD3_YEASTTAD3genetic
27708008
GPI12_YEASTGPI12genetic
27708008
NOG2_YEASTNOG2genetic
27708008
RPB2_YEASTRPB2genetic
27708008
CLP1_YEASTCLP1genetic
27708008
MOT1_YEASTMOT1genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SLI1_YEAST

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Related Literatures of Post-Translational Modification

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