COS10_YEAST - dbPTM
COS10_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID COS10_YEAST
UniProt AC P52924
Protein Name Protein COS10
Gene Name COS10
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 374
Subcellular Localization Membrane
Multi-pass membrane protein.
Protein Description
Protein Sequence MGEEIRLLSSKGLETHSSFCLPEDIFRNRLTWLCSEIRNSGFWIWSLSWLPLAVWWGMASTWFYPLLTSVVLILALIAILPVVQIQYSKYTLSNQLTQLSKEIIKSAPGAYSADWDAVAIHFNSYLYENKAWKTAHFFFNGTDCQEAFRKTILEPAVLRRQNEDPRFSSIEILVPYTEDAVQVYFTKVNAQWRLIHGKKECKLTMLENVKLPKETYRCKLAWSCQRIRISFSPLDFLPDMSDFFICANLSPACLVSYWLIDIFFRMIDDFQNIRPKSMKVDDKMQYLSDIINEQGASPEKWDTIARKTNTRLFEKRVWKNEEFFFDGTDCQAFFERNFSSLLFSKKSASPRSLNVELWKYIQEAQLSCNYEPLP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
339PhosphorylationAFFERNFSSLLFSKK
HHHHHCHHHHHHCCC		24.5128152593
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of COS10_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of COS10_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of COS10_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TSC3_YEASTTSC3genetic
16269340
PEX29_YEASTPEX29physical
18719252
AVT1_YEASTAVT1physical
16093310
VPS41_YEASTVPS41genetic
20526336
HSP72_YEASTSSA2physical
22940862
HSP71_YEASTSSA1physical
22940862
MRM2_YEASTMRM2genetic
27708008
ASK10_YEASTASK10genetic
27708008
CUL8_YEASTRTT101genetic
27708008
RL43A_YEASTRPL43Bgenetic
27708008
RL43B_YEASTRPL43Bgenetic
27708008
BUL2_YEASTBUL2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of COS10_YEAST

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Related Literatures of Post-Translational Modification

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