YME2_YEAST - dbPTM
YME2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID YME2_YEAST
UniProt AC P32843
Protein Name Mitochondrial escape protein 2
Gene Name YME2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 850
Subcellular Localization Mitochondrion inner membrane
Single-pass membrane protein .
Protein Description Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA..
Protein Sequence MLLVRTTSLNVSRMPVPCLARGIGILKGKYRLANLMNAQPSVRHVSSEIQQKDQQAGESNTATDTGVIHKSDEETLIYFDNVYARTTSVWNPTLWYNLLLRNQSRDAVREKIRNLASPPNNPIYGLELKSTIPVKRDGGVFATFVVPPKYTKAQVNSLIQQNTARESSKNLLSYFTRASAFPVKGSPWIEDLRRLPSTTIVIKFQGPALTEEEIYSLFRRYGTIIDIFPPTAANNNVAKVRYRSFRGAISAKNCVSGIEIHNTVLHIQYENIRRGHLVSNFFTNHTRIAIPVLFALLSIFAVLVFDPIREFSIEQKITHKYSLSWDNKFWKQLKTLTSSTMTSIKYYWGGPDDNHQRKHLWEERIEKVNDLKMWLEENNNTFVVIRGPRGSGKHDLVMQHTLQNRANVLYLDCDKLIKSRTDPMFLKNAASQLGYFPIFPWIDSVTGVLDLTVQGLTGQKTGLSETKESRFRNMLTTSLMSIRRIALKNYKAFVSTGDGTVNVKEEDYLQQHPEAKPVIVIDRFEGKSEINGFVYKELSDWAAMLVQMNIAHVIFLTETVASNQRLSESLPNQVFKNLILSDASKENSRNYVLSQLEDYLYYNKKSKGENVKEPESEKETAENNDSDSEADTSVKKAEVILNEKELQEIDASLEPLGGRMLDLQAFVRRVKSGEEPSEAVDKMIEQASEQITQMFLSDKIDSNKSAQAWELIELLSANPVIPFHEIVNKPLFKAAPETGIMELENNGLITVSRDRGVLQEIRPAKPLYRAAFTYLINDPELAKVLKTRYLLKVVGFETGRIKKWEEELKPLGKVPDQKLFKTRLDYLSGKINASNAVITKCEEEIKNLSK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
129AcetylationPIYGLELKSTIPVKR
CCCCEEEEEEEEEEE		35.8624489116
244PhosphorylationVAKVRYRSFRGAISA
EEEEEECCHHCCCCC		15.4527017623
335PhosphorylationKFWKQLKTLTSSTMT
HHHHHHHHHCCCCCC		43.8127017623
476PhosphorylationSRFRNMLTTSLMSIR
HHHHHHHHHHHHHHH		11.9930377154
477PhosphorylationRFRNMLTTSLMSIRR
HHHHHHHHHHHHHHH		18.8527017623
478PhosphorylationFRNMLTTSLMSIRRI
HHHHHHHHHHHHHHH		19.4827017623
591PhosphorylationSKENSRNYVLSQLED
CCCCCCHHHHHHHHH		11.1430377154
599PhosphorylationVLSQLEDYLYYNKKS
HHHHHHHHHHHCCCC		6.2930377154
601PhosphorylationSQLEDYLYYNKKSKG
HHHHHHHHHCCCCCC		9.9630377154
620PhosphorylationEPESEKETAENNDSD
CCHHHHHHHHCCCCC		50.7928889911
626PhosphorylationETAENNDSDSEADTS
HHHHCCCCCCHHHHH		45.2027717283
628PhosphorylationAENNDSDSEADTSVK
HHCCCCCCHHHHHHH		38.3427717283
632PhosphorylationDSDSEADTSVKKAEV
CCCCHHHHHHHHHHH		42.3328889911
809AcetylationKKWEEELKPLGKVPD
HHHHHHCCCCCCCCC		41.2924489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of YME2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of YME2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of YME2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ORN_YEASTREX2genetic
9933355
ILV5_YEASTILV5genetic
16850347
TAD3_YEASTTAD3genetic
19061648
CDC73_YEASTCDC73genetic
19061648
ARC1_YEASTARC1genetic
19061648
LTV1_YEASTLTV1genetic
19061648
SAP30_YEASTSAP30genetic
19061648
RU1A_YEASTMUD1genetic
19061648
NOP8_YEASTNOP8genetic
19061648
RIA1_YEASTRIA1genetic
19061648
DBP2_YEASTDBP2genetic
19061648
HRB1_YEASTHRB1genetic
19061648
PUS1_YEASTPUS1genetic
19061648
CWC27_YEASTCWC27genetic
19061648
LSM12_YEASTLSM12genetic
19061648
YBF9_YEASTYBL059Wgenetic
20093466
GLRX7_YEASTGRX7genetic
20093466
YBU0_YEASTYBR090Cgenetic
20093466
MCFS2_YEASTEHT1genetic
20093466
MBA1_YEASTMBA1genetic
20093466
MGR1_YEASTMGR1genetic
20093466
MTU1_YEASTSLM3genetic
20093466
SSD1_YEASTSSD1genetic
20093466
AIM11_YEASTAIM11genetic
20093466
MTC3_YEASTMTC3genetic
20093466
GEP7_YEASTGEP7genetic
20093466
PCP1_YEASTPCP1genetic
20093466
SET2_YEASTSET2genetic
20093466
AIM25_YEASTAIM25genetic
20093466
MDM35_YEASTMDM35genetic
20093466
COX12_YEASTCOX12genetic
20093466
SIC1_YEASTSIC1genetic
20093466
COQ11_YEASTYLR290Cgenetic
20093466
RCF1_YEASTRCF1genetic
20093466
MGR3_YEASTMGR3genetic
20093466
MLH1_YEASTMLH1genetic
20093466
PET8_YEASTPET8genetic
20093466
MDM38_YEASTMDM38genetic
20093466
COQ7_YEASTCAT5genetic
20093466
PNT1_YEASTPNT1genetic
20093466
RS10A_YEASTRPS10Agenetic
20093466
MNE1_YEASTMNE1genetic
20093466
MRX4_YEASTYPL168Wgenetic
20093466
EAF3_YEASTEAF3genetic
20093466
YME1_YEASTYME1genetic
20093466
YP098_YEASTYPR098Cgenetic
20093466
QCR2_YEASTQCR2genetic
20093466
MBA1_YEASTMBA1genetic
21987634
MGR1_YEASTMGR1genetic
21987634
AIM11_YEASTAIM11genetic
21987634
PHB1_YEASTPHB1genetic
21987634
GEP4_YEASTGEP4genetic
21987634
MDM35_YEASTMDM35genetic
21987634
UPS1_YEASTUPS1genetic
21987634
MGR3_YEASTMGR3genetic
21987634
SAP30_YEASTSAP30genetic
21987634
MDM38_YEASTMDM38genetic
21987634
YME1_YEASTYME1genetic
21987634
SEC7_YEASTSEC7genetic
27708008
SEC12_YEASTSEC12genetic
27708008
GPT1_YEASTSCT1genetic
27708008
YBF9_YEASTYBL059Wgenetic
27708008
MCFS2_YEASTEHT1genetic
27708008
MBA1_YEASTMBA1genetic
27708008
MGR1_YEASTMGR1genetic
27708008
MTU1_YEASTSLM3genetic
27708008
AIM11_YEASTAIM11genetic
27708008
YG036_YEASTYGL036Wgenetic
27708008
GEP7_YEASTGEP7genetic
27708008
MTC3_YEASTMTC3genetic
27708008
ASK10_YEASTASK10genetic
27708008
PHB1_YEASTPHB1genetic
27708008
RSSA1_YEASTRPS0Agenetic
27708008
MRX5_YEASTYJL147Cgenetic
27708008
SET2_YEASTSET2genetic
27708008
MDM35_YEASTMDM35genetic
27708008
CBT1_YEASTCBT1genetic
27708008
COX12_YEASTCOX12genetic
27708008
SIC1_YEASTSIC1genetic
27708008
RL37A_YEASTRPL37Agenetic
27708008
UBX2_YEASTUBX2genetic
27708008
RCF1_YEASTRCF1genetic
27708008
RCO1_YEASTRCO1genetic
27708008
MGR3_YEASTMGR3genetic
27708008
MLH1_YEASTMLH1genetic
27708008
PET8_YEASTPET8genetic
27708008
MDM38_YEASTMDM38genetic
27708008
DIA2_YEASTDIA2genetic
27708008
MNE1_YEASTMNE1genetic
27708008
MRX4_YEASTYPL168Wgenetic
27708008
NEW1_YEASTNEW1genetic
27708008
EAF3_YEASTEAF3genetic
27708008
YP098_YEASTYPR098Cgenetic
27708008
KAR3_YEASTKAR3genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of YME2_YEAST

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Related Literatures of Post-Translational Modification

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