OMA1_YEAST - dbPTM
OMA1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID OMA1_YEAST
UniProt AC P36163
Protein Name Mitochondrial metalloendopeptidase OMA1
Gene Name OMA1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 345
Subcellular Localization Mitochondrion inner membrane
Multi-pass membrane protein .
Protein Description Protease that is part of the quality control system in the inner membrane of mitochondria. Cleaves and thereby promotes the turnover of mistranslated or misfolded membrane proteins. Can cleave the misfolded multi-pass membrane protein OXA1..
Protein Sequence MLRNIIRFKGFGKGTSGGFLKPVSFRVQLTRCYRYDNGPSYRRFNNGEYSQKSSFKSILLDKSSRKYLALLFGGCSLFYYTHLDKAPVSDRSRFIWVSRPLELTIGNYTYKSIWRQTQQEILPPQHPLSIKIENIFMKIVEAAYKDPSVDNSLLDGIKWEIHVVNDPTASPNAFVLPGGKVFIFSSILPICANDDGIATVLAHEFAHQLARHTAENLSKAPIYSLLGLVLYTVTGAHAINNILLDGFLRMPASRQMETEADYIGLMIMSRACFQPQESIKVWERMANFEKQMNRGGVVNMEFLSTHPASTRRIENMSKWLPKANEIYEQSDCSSMGNYYKSFFSM
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
98PhosphorylationRSRFIWVSRPLELTI
CCCEEEEECCEEEEE		17.1226447709
138AcetylationKIENIFMKIVEAAYK
EEEHHHHHHHHHHHC		32.6224489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of OMA1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of OMA1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of OMA1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SRS2_YEASTSRS2genetic
21459050
SHY1_YEASTSHY1genetic
22219186
SODM_YEASTSOD2genetic
24648523
OMA1_YEASTOMA1physical
24648523
AFG3_YEASTAFG3genetic
24648523
YME1_YEASTYME1genetic
24648523
PCP1_YEASTPCP1genetic
24648523
AFG1_YEASTAFG1genetic
24648523
LONM_YEASTPIM1genetic
24648523
PRS6A_YEASTRPT5genetic
27325672
RIM15_YEASTRIM15genetic
27325672
TOR1_YEASTTOR1genetic
27325672
MSN2_YEASTMSN2genetic
27325672
MSN4_YEASTMSN4genetic
27325672
GIS1_YEASTGIS1genetic
27325672
PP2A1_YEASTPPH21genetic
27325672
PP2A2_YEASTPPH22genetic
27325672
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of OMA1_YEAST

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Related Literatures of Post-Translational Modification

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