dbPTM

SCO2_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SCO2_YEAST
UniProt AC	P38072
Protein Name	Protein SCO2, mitochondrial
Gene Name	SCO2
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	301
Subcellular Localization	Mitochondrion inner membrane.
Protein Description	Acts as a copper chaperone, transporting copper to the Cu(A) site on the cytochrome c oxidase subunit II (COX2)..
Protein Sequence	MLNSSRKYACRSLFRQANVSIKGLFYNGGAYRRGFSTGCCLRSDNKESPSARQPLDRLQLGDEINEPEPIRTRFFQFSRWKATIALLLLSGGTYAYLSRKRRLLETEKEADANRAYGSVALGGPFNLTDFNGKPFTEENLKGKFSILYFGFSHCPDICPEELDRLTYWISELDDKDHIKIQPLFISCDPARDTPDVLKEYLSDFHPAIIGLTGTYDQVKSVCKKYKVYFSTPRDVKPNQDYLVDHSIFFYLIDPEGQFIDALGRNYDEQSGLEKIREQIQAYVPKEERERRSKKWYSFIFN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
226	Acetylation	KSVCKKYKVYFSTPR HHHHHHCEEEECCCC	39.06	22865919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SCO2_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SCO2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SCO2_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SCO1_YEAST	SCO1	physical	12125048
SCO2_YEAST	SCO2	physical	12125048
YPQ3_YEAST	RTC2	genetic	20093466
UBX7_YEAST	UBX7	genetic	20093466
LRE1_YEAST	LRE1	genetic	20093466
YCE9_YEAST	YCL049C	genetic	20093466
RV161_YEAST	RVS161	genetic	20093466
SNT1_YEAST	SNT1	genetic	20093466
QRI7_YEAST	QRI7	genetic	20093466
UBC13_YEAST	UBC13	genetic	20093466
ASK10_YEAST	ASK10	genetic	20093466
MED20_YEAST	SRB2	genetic	20093466
AIM18_YEAST	AIM18	genetic	20093466
IXR1_YEAST	IXR1	genetic	20093466
YL415_YEAST	YLR415C	genetic	20093466
MSS1_YEAST	MSS1	genetic	20093466
MGR3_YEAST	MGR3	genetic	20093466
COA6_YEAST	COA6	genetic	20093466
PHO23_YEAST	PHO23	genetic	20093466
ASI3_YEAST	ASI3	genetic	20093466
IRA2_YEAST	IRA2	genetic	20093466
SIN3_YEAST	SIN3	genetic	20093466
PNT1_YEAST	PNT1	genetic	20093466
PDE2_YEAST	PDE2	genetic	20093466
MGR1_YEAST	MGR1	genetic	27708008
RV161_YEAST	RVS161	genetic	27708008
SNT1_YEAST	SNT1	genetic	27708008
IMG2_YEAST	IMG2	genetic	27708008
TRM3_YEAST	TRM3	genetic	27708008
YD157_YEAST	YDL157C	genetic	27708008
BEM2_YEAST	BEM2	genetic	27708008
MED20_YEAST	SRB2	genetic	27708008
AIM18_YEAST	AIM18	genetic	27708008
IXR1_YEAST	IXR1	genetic	27708008
YL415_YEAST	YLR415C	genetic	27708008
MGR3_YEAST	MGR3	genetic	27708008
COA6_YEAST	COA6	genetic	27708008
ASI3_YEAST	ASI3	genetic	27708008
SIN3_YEAST	SIN3	genetic	27708008
PNT1_YEAST	PNT1	genetic	27708008
PDE2_YEAST	PDE2	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SCO2_YEAST

Related Literatures of Post-Translational Modification