dbPTM

SCO1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SCO1_YEAST
UniProt AC	P23833
Protein Name	Protein SCO1, mitochondrial
Gene Name	SCO1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	295
Subcellular Localization	Mitochondrion inner membrane .
Protein Description	Required for the accumulation of subunits 1 and 2 of cytochrome c oxidase complex. Thought to play a role in either mitochondrial copper transport or insertion of copper into the active site of COX..
Protein Sequence	MLKLSRSANLRLVQLPAARLSGNGAKLLTQRGFFTVTRLWQSNGKKPLSRVPVGGTPIKDNGKVREGSIEFSTGKAIALFLAVGGALSYFFNREKRRLETQKEAEANRGYGKPSLGGPFHLEDMYGNEFTEKNLLGKFSIIYFGFSNCPDICPDELDKLGLWLNTLSSKYGITLQPLFITCDPARDSPAVLKEYLSDFHPSILGLTGTFDEVKNACKKYRVYFSTPPNVKPGQDYLVDHSIFFYLMDPEGQFVDALGRNYDEKTGVDKIVEHVKSYVPAEQRAKQKEAWYSFLFK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
68	Phosphorylation	NGKVREGSIEFSTGK CCEECCEEEEECCHH	17.75	27214570

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SCO1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SCO1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SCO1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
COX2_YEAST	COX2	physical	11086158
SCO1_YEAST	SCO1	physical	11086158
COX2_YEAST	COX2	physical	11546815
COX15_YEAST	COX15	genetic	17430883
AFG1_YEAST	AFG1	genetic	17430883
MET7_YEAST	STR2	genetic	17430883
GPB2_YEAST	GPB2	genetic	20093466
RXT3_YEAST	RXT3	genetic	20093466
PAA1_YEAST	PAA1	genetic	20093466
SEM1_YEAST	SEM1	genetic	20093466
AAKG_YEAST	SNF4	genetic	20093466
GYP2_YEAST	MDR1	genetic	20093466
HSV2_YEAST	HSV2	genetic	20093466
FYV10_YEAST	FYV10	genetic	20093466
URM1_YEAST	URM1	genetic	20093466
MHP1_YEAST	MHP1	genetic	20093466
YJ90_YEAST	YJR120W	genetic	20093466
ERG3_YEAST	ERG3	genetic	20093466
SRN2_YEAST	SRN2	genetic	20093466
UPS1_YEAST	UPS1	genetic	20093466
SEC72_YEAST	SEC72	genetic	20093466
ATP10_YEAST	ATP10	genetic	20093466
ATP18_YEAST	ATP18	genetic	20093466
AMPD_YEAST	AMD1	genetic	20093466
SIP5_YEAST	SIP5	genetic	20093466
PFKA2_YEAST	PFK2	genetic	20093466
AEP2_YEAST	AEP2	genetic	20093466
ATP23_YEAST	ATP23	genetic	20093466
YO13A_YEAST	YOL013W-A	genetic	20093466
ROD1_YEAST	ROD1	genetic	20093466
DFG16_YEAST	DFG16	genetic	20093466
WHI5_YEAST	WHI5	genetic	20093466
SCO2_YEAST	SCO2	genetic	21821119
COX11_YEAST	COX11	genetic	21821119
CATT_YEAST	CTT1	genetic	21821119
CATA_YEAST	CTA1	genetic	21821119
EXO70_YEAST	EXO70	genetic	27708008
PP2C1_YEAST	PTC1	genetic	27708008
BDF2_YEAST	BDF2	genetic	27708008
RXT3_YEAST	RXT3	genetic	27708008
PNPP_YEAST	PHO13	genetic	27708008
VHS1_YEAST	VHS1	genetic	27708008
GNTK_YEAST	YDR248C	genetic	27708008
PCL6_YEAST	PCL6	genetic	27708008
IES1_YEAST	IES1	genetic	27708008
HSV2_YEAST	HSV2	genetic	27708008
URM1_YEAST	URM1	genetic	27708008
KAPA_YEAST	TPK1	genetic	27708008
HIR3_YEAST	HIR3	genetic	27708008
MDM35_YEAST	MDM35	genetic	27708008
MEH1_YEAST	MEH1	genetic	27708008
ERG3_YEAST	ERG3	genetic	27708008
AVL9_YEAST	AVL9	genetic	27708008
YL125_YEAST	YLR125W	genetic	27708008
AMPD_YEAST	AMD1	genetic	27708008
NTE1_YEAST	NTE1	genetic	27708008
YM100_YEAST	YML100W-A	genetic	27708008
SWS2_YEAST	SWS2	genetic	27708008
ROD1_YEAST	ROD1	genetic	27708008
CY1_YEAST	CYT1	genetic	27708008
HSP7F_YEAST	SSE1	genetic	27708008
MCES_YEAST	ABD1	genetic	27708008
UAP1_YEAST	QRI1	genetic	27708008
GLE1_YEAST	GLE1	genetic	27708008
TIM22_YEAST	TIM22	genetic	27708008
TCPA_YEAST	TCP1	genetic	27708008
PCF11_YEAST	PCF11	genetic	27708008
RSP5_YEAST	RSP5	genetic	27708008
MOB2_YEAST	MOB2	genetic	27708008
YPT1_YEAST	YPT1	genetic	27708008
ACT_YEAST	ACT1	genetic	27708008
PRS8_YEAST	RPT6	genetic	27708008
SWC4_YEAST	SWC4	genetic	27708008
CBF3A_YEAST	CBF2	genetic	27708008
MED6_YEAST	MED6	genetic	27708008
STS1_YEAST	STS1	genetic	27708008
NU192_YEAST	NUP192	genetic	27708008
TIM16_YEAST	PAM16	genetic	27708008
CDC11_YEAST	CDC11	genetic	27708008
SSL1_YEAST	SSL1	genetic	27708008
RU1C_YEAST	YHC1	genetic	27708008
TAD3_YEAST	TAD3	genetic	27708008
ARP9_YEAST	ARP9	genetic	27708008
LST8_YEAST	LST8	genetic	27708008
CAP_YEAST	SRV2	genetic	27708008
CLP1_YEAST	CLP1	genetic	27708008
PRP4_YEAST	PRP4	genetic	27708008
VPS8_YEAST	VPS8	genetic	27708008
DEP1_YEAST	DEP1	genetic	27708008
GPB2_YEAST	GPB2	genetic	27708008
YA065_YEAST	YAL065C	genetic	27708008
FTH1_YEAST	FTH1	genetic	27708008
RER1_YEAST	RER1	genetic	27708008
MXR2_YEAST	MXR2	genetic	27708008
CISY2_YEAST	CIT2	genetic	27708008
RV161_YEAST	RVS161	genetic	27708008
FUB1_YEAST	FUB1	genetic	27708008
THI3_YEAST	THI3	genetic	27708008
PAA1_YEAST	PAA1	genetic	27708008
PP4C_YEAST	PPH3	genetic	27708008
AFR1_YEAST	AFR1	genetic	27708008
PMP3_YEAST	PMP3	genetic	27708008
SEM1_YEAST	SEM1	genetic	27708008
LSM6_YEAST	LSM6	genetic	27708008
SAK1_YEAST	SAK1	genetic	27708008
YFF1_YEAST	YFL051C	genetic	27708008
IGD1_YEAST	IGD1	genetic	27708008
SGF73_YEAST	SGF73	genetic	27708008
MPC1_YEAST	MPC1	genetic	27708008
AAKG_YEAST	SNF4	genetic	27708008
CWC26_YEAST	BUD13	genetic	27708008
KSS1_YEAST	KSS1	genetic	27708008
ASK10_YEAST	ASK10	genetic	27708008
GYP2_YEAST	MDR1	genetic	27708008
GOSR1_YEAST	GOS1	genetic	27708008
MED20_YEAST	SRB2	genetic	27708008
SMF2_YEAST	SMF2	genetic	27708008
CRP1_YEAST	CRP1	genetic	27708008
PIG2_YEAST	PIG2	genetic	27708008
SDS3_YEAST	SDS3	genetic	27708008
RT25_YEAST	RSM25	genetic	27708008
FYV10_YEAST	FYV10	genetic	27708008
MHP1_YEAST	MHP1	genetic	27708008
TAX4_YEAST	TAX4	genetic	27708008
SET2_YEAST	SET2	genetic	27708008
PTK2_YEAST	PTK2	genetic	27708008
VPS24_YEAST	VPS24	genetic	27708008
DOA1_YEAST	DOA1	genetic	27708008
FRE2_YEAST	FRE2	genetic	27708008
TGL4_YEAST	TGL4	genetic	27708008
BAS1_YEAST	BAS1	genetic	27708008
RT109_YEAST	RTT109	genetic	27708008
HOG1_YEAST	HOG1	genetic	27708008
SRN2_YEAST	SRN2	genetic	27708008
UPS1_YEAST	UPS1	genetic	27708008
YL271_YEAST	YLR271W	genetic	27708008
SEC72_YEAST	SEC72	genetic	27708008
ATP10_YEAST	ATP10	genetic	27708008
YL422_YEAST	YLR422W	genetic	27708008
GAL80_YEAST	GAL80	genetic	27708008
ATP18_YEAST	ATP18	genetic	27708008
PHO84_YEAST	PHO84	genetic	27708008
MSC1_YEAST	MSC1	genetic	27708008
RCO1_YEAST	RCO1	genetic	27708008
RIM11_YEAST	RIM11	genetic	27708008
SIP5_YEAST	SIP5	genetic	27708008
TPP1_YEAST	TPP1	genetic	27708008
PFKA2_YEAST	PFK2	genetic	27708008
UBP8_YEAST	UBP8	genetic	27708008
AEP2_YEAST	AEP2	genetic	27708008
SIW14_YEAST	SIW14	genetic	27708008
TOM7_YEAST	TOM7	genetic	27708008
ATP23_YEAST	ATP23	genetic	27708008
SGT2_YEAST	SGT2	genetic	27708008
HIR2_YEAST	HIR2	genetic	27708008
WHI2_YEAST	WHI2	genetic	27708008
STD1_YEAST	STD1	genetic	27708008
RTC5_YEAST	RTC5	genetic	27708008
GAC1_YEAST	GAC1	genetic	27708008
RS10A_YEAST	RPS10A	genetic	27708008
GPB1_YEAST	GPB1	genetic	27708008
SUR1_YEAST	SUR1	genetic	27708008
UME1_YEAST	UME1	genetic	27708008
CTI6_YEAST	CTI6	genetic	27708008
MRN1_YEAST	MRN1	genetic	27708008
VPS4_YEAST	VPS4	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SCO1_YEAST

Related Literatures of Post-Translational Modification