dbPTM

COX11_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	COX11_YEAST
UniProt AC	P19516
Protein Name	Cytochrome c oxidase assembly protein COX11, mitochondrial
Gene Name	COX11
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	300
Subcellular Localization	Mitochondrion inner membrane Single-pass membrane protein Intermembrane side . Intrinsic component of the inner-membrane.
Protein Description	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I..
Protein Sequence	MIRICPIVRSKVPLLGTFLRSDSWLAPHALALRRAICKNVALRSYSVNSEQPKHTFDISKLTRNEIQQLRELKRARERKFKDRTVAFYFSSVAVLFLGLAYAAVPLYRAICARTGFGGIPITDRRKFTDDKLIPVDTEKRIRISFTSEVSQILPWKFVPQQREVYVLPGETALAFYKAKNYSDKDIIGMATYSIAPGEAAQYFNKIQCFCFEEQKLAAGEEIDMPVFFFIDPDFASDPAMRNIDDIILHYTFFRAHYGDGTAVSDSKKEPEMNADEKAASLANAAILSPEVIDTRKDNSN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
288	Phosphorylation	LANAAILSPEVIDTR HHHHHHHCHHHHCCC	16.95	27017623

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of COX11_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of COX11_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of COX11_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RM36_YEAST	MRPL36	physical	15776235
COX14_YEAST	COX14	genetic	17430883
PT309_YEAST	PET309	genetic	17430883
COX15_YEAST	COX15	genetic	17430883
AFG1_YEAST	AFG1	genetic	17430883
MET7_YEAST	STR2	genetic	17430883
COA2_YEAST	COA2	genetic	18541668
COX10_YEAST	COX10	genetic	18541668
SHY1_YEAST	SHY1	genetic	18541668
DHSD_YEAST	SDH4	physical	16093310
ERV14_YEAST	ERV14	physical	16093310
COA3_YEAST	COA3	genetic	21068384
CATT_YEAST	CTT1	genetic	21821119
CATA_YEAST	CTA1	genetic	21821119
KPYK1_YEAST	CDC19	physical	22940862
DED1_YEAST	DED1	physical	22940862
ENO2_YEAST	ENO2	physical	22940862
SSB1_YEAST	SSB1	physical	22940862
HSP72_YEAST	SSA2	physical	22940862
MAK5_YEAST	MAK5	genetic	27708008
POP7_YEAST	POP7	genetic	27708008
TIM22_YEAST	TIM22	genetic	27708008
CDC1_YEAST	CDC1	genetic	27708008
GPI11_YEAST	GPI11	genetic	27708008
RSP5_YEAST	RSP5	genetic	27708008
CCA1_YEAST	CCA1	genetic	27708008
YPT1_YEAST	YPT1	genetic	27708008
ACT_YEAST	ACT1	genetic	27708008
ARPC5_YEAST	ARC15	genetic	27708008
TIM16_YEAST	PAM16	genetic	27708008
SYFB_YEAST	FRS1	genetic	27708008
BOS1_YEAST	BOS1	genetic	27708008
CFT2_YEAST	CFT2	genetic	27708008
PRS10_YEAST	RPT4	genetic	27708008
PT117_YEAST	PET117	genetic	27998984
COX19_YEAST	COX19	physical	25926683

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of COX11_YEAST

Related Literatures of Post-Translational Modification