| UniProt ID | ATPJ_YEAST | |
|---|---|---|
| UniProt AC | P81449 | |
| Protein Name | ATP synthase subunit e, mitochondrial | |
| Gene Name | TIM11 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 96 | |
| Subcellular Localization | Mitochondrion. Mitochondrion inner membrane. | |
| Protein Description | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.. | |
| Protein Sequence | MSTVNVLRYSALGLGLFFGFRNDMILKCNAKKKEEQAQYEEKLKLVEEAKKEYAKLHPVVTPKDVPANASFNLEDPNIDFERVILNAVESLKEAST | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MSTVNVLRY ------CCHHHHHHH | 40.85 | 9857174 | |
| 39 | Phosphorylation | KKEEQAQYEEKLKLV HHHHHHHHHHHHHHH | 29.13 | 27214570 | |
| 50 | 2-Hydroxyisobutyrylation | LKLVEEAKKEYAKLH HHHHHHHHHHHHHHC | 49.79 | - | |
| 50 | Succinylation | LKLVEEAKKEYAKLH HHHHHHHHHHHHHHC | 49.79 | 23954790 | |
| 70 | Phosphorylation | KDVPANASFNLEDPN CCCCCCCCCCCCCCC | 17.93 | 30377154 | |
| 90 | Phosphorylation | VILNAVESLKEAST- HHHHHHHHHHHHCC- | 37.84 | 24909858 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ATPJ_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ATPJ_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ATPJ_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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