| UniProt ID | MGM1_YEAST | |
|---|---|---|
| UniProt AC | P32266 | |
| Protein Name | Dynamin-like GTPase MGM1, mitochondrial | |
| Gene Name | MGM1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 881 | |
| Subcellular Localization |
Dynamin-like GTPase MGM1 large isoform: Mitochondrion inner membrane Single-pass type II membrane protein Intermembrane side . Mitochondrion intermembrane space . Dynamin-like GTPase MGM1 small isoform: Mitochondrion inner membrane Peripheral membr |
|
| Protein Description | Dynamin-related GTPase required for mitochondrial fusion. Coordinates interaction between the inner and outer mitochondrial membrane to promote the formation of the double membrane.. | |
| Protein Sequence | MNASPVRLLILRRQLATHPAILYSSPYIKSPLVHLHSRMSNVHRSAHANALSFVITRRSISHFPKIISKIIRLPIYVGGGMAAAGSYIAYKMEEASSFTKDKLDRIKDLGESMKEKFNKMFSGDKSQDGGHGNDGTVPTATLIAATSLDDDESKRQGDPKDDDDEDDDDEDDENDSVDTTQDEMLNLTKQMIEIRTILNKVDSSSAHLTLPSIVVIGSQSSGKSSVLESIVGREFLPKGSNMVTRRPIELTLVNTPNSNNVTADFPSMRLYNIKDFKEVKRMLMELNMAVPTSEAVSEEPIQLTIKSSRVPDLSLVDLPGYIQVEAADQPIELKTKIRDLCEKYLTAPNIILAISAADVDLANSSALKASKAADPKGLRTIGVITKLDLVDPEKARSILNNKKYPLSMGYVGVITKTPSSINRKHLGLFGEAPSSSLSGIFSKGQHGQSSGEENTNGLKQIVSHQFEKAYFKENKKYFTNCQVSTKKLREKLIKILEISMSNALEPTSTLIQQELDDTSYLFKVEFNDRHLTPKSYLLNNIDVLKLGIKEFQEKFHRNELKSILRAELDQKVLDVLATRYWKDDNLQDLSSSKLESDTDMLYWHKKLELASSGLTKMGIGRLSTMLTTNAILKELDNILESTQLKNHELIKDLVSNTAINVLNSKYYSTADQVENCIKPFKYEIDLEERDWSLARQHSINLIKEELRQCNSRYQAIKNAVGSKKLANVMGYLENESNLQKETLGMSKLLLERGSEAIFLDKRCKVLSFRLKMLKNKCHSTIEKDRCPEVFLSAVSDKLTSTAVLFLNVELLSDFFYNFPIELDRRLTLLGDEQVEMFAKEDPKISRHIELQKRKELLELALEKIDSILVFKKSYKGVSKNL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 122 | Phosphorylation | EKFNKMFSGDKSQDG HHHHHHHCCCCCCCC | 42.45 | 27017623 | |
| 179 | Phosphorylation | DENDSVDTTQDEMLN CCCCCCCCHHHHHHH | 24.97 | 25371407 | |
| 180 | Phosphorylation | ENDSVDTTQDEMLNL CCCCCCCHHHHHHHH | 29.56 | 25371407 | |
| 274 | Succinylation | SMRLYNIKDFKEVKR CCEECCCCCHHHHHH | 54.17 | 23954790 | |
| 274 | Acetylation | SMRLYNIKDFKEVKR CCEECCCCCHHHHHH | 54.17 | 24489116 | |
| 277 | Acetylation | LYNIKDFKEVKRMLM ECCCCCHHHHHHHHH | 72.27 | 24489116 | |
| 407 | Phosphorylation | NNKKYPLSMGYVGVI CCCCCCCCCCEEEEE | 12.98 | 21440633 | |
| 435 | Phosphorylation | LFGEAPSSSLSGIFS EECCCCCCCCCCCCC | 33.95 | 24961812 | |
| 436 | Phosphorylation | FGEAPSSSLSGIFSK ECCCCCCCCCCCCCC | 30.78 | 24961812 | |
| 438 | Phosphorylation | EAPSSSLSGIFSKGQ CCCCCCCCCCCCCCC | 31.61 | 21440633 | |
| 442 | Phosphorylation | SSLSGIFSKGQHGQS CCCCCCCCCCCCCCC | 33.68 | 24961812 | |
| 545 | Ubiquitination | LNNIDVLKLGIKEFQ HCCHHHHHHCHHHHH | 44.51 | 22817900 | |
| 549 | Ubiquitination | DVLKLGIKEFQEKFH HHHHHCHHHHHHHHH | 51.15 | 23749301 | |
| 554 | Ubiquitination | GIKEFQEKFHRNELK CHHHHHHHHHHHHHH | 35.37 | 22817900 | |
| 562 | Phosphorylation | FHRNELKSILRAELD HHHHHHHHHHHHHHH | 39.21 | 28889911 | |
| 571 | Ubiquitination | LRAELDQKVLDVLAT HHHHHHHHHHHHHHH | 44.42 | 24961812 | |
| 703 | Acetylation | QHSINLIKEELRQCN HHHHHHHHHHHHHCH | 48.58 | 24489116 | |
| 873 | Phosphorylation | SILVFKKSYKGVSKN CEEEECHHHCCCCCC | 32.44 | 27017623 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MGM1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MGM1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MGM1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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