ECM7_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ECM7_YEAST
• UniProt AC: Q06200
• Protein Name: Protein ECM7
• Gene Name: ECM7
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 448
• Subcellular Localization: Membrane; Multi-pass membrane protein.
• Protein Description: May be involved in cell wall organization and biogenesis..
• Protein Sequence: MVMSRIRDTIARPFQNLTALEKVVQWLRLGTTLLIISFGLALTVGPLSSPRTLYMSRLDTYSADITTGLFTVLRESMEQSTSTEENNGVGLTTSELYILTAYTESQIKNVPQYITVSLYGRCDSTYTMVEVFDSEGNMHSVKNSTTKSTCSSIGTDYLFDYREVLESLGLDIILDYAYNKIGSQQAESSAYTTYMRSLKHKKANVLHLLYAVISFQVCMLFFMIWYYYIKGRFMNALKERALVHINSLLSLVVFIGGLISSISLAWVNYTIQSRINTELEAFGFSYHLGVTWFALLWCFAGLISVSCLAWSGLEWCISDNGTSYGGGIDDKFLGYQAGVFTDADLDDETSYSQRYPQRQSTSGEAELMRNSDTMATIRKTSDVDLNSENDANTSLDHGNPTANISNGGKHEPFATREEFELQDIRFRSSNDSEESMQRVIKPSSALQF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
125	Phosphorylation	LYGRCDSTYTMVEVF EECCCCCEEEEEEEE	15.12	27017623
126	Phosphorylation	YGRCDSTYTMVEVFD ECCCCCEEEEEEEEC	9.22	27017623
127	Phosphorylation	GRCDSTYTMVEVFDS CCCCCEEEEEEEECC	18.15	27017623
360	Phosphorylation	QRYPQRQSTSGEAEL HHCCCCCCCCCCHHH	27.08	23749301
361	Phosphorylation	RYPQRQSTSGEAELM HCCCCCCCCCCHHHH	32.20	30377154
379	Ubiquitination	DTMATIRKTSDVDLN CCHHEEEECCCCCCC	48.83	23749301
381	Phosphorylation	MATIRKTSDVDLNSE HHEEEECCCCCCCCC	38.38	23749301
387	Phosphorylation	TSDVDLNSENDANTS CCCCCCCCCCCCCCC	45.11	23749301
393	Phosphorylation	NSENDANTSLDHGNP CCCCCCCCCCCCCCC	32.18	23749301
394	Phosphorylation	SENDANTSLDHGNPT CCCCCCCCCCCCCCC	31.44	23749301
428	Phosphorylation	LQDIRFRSSNDSEES EEECEECCCCCCHHH	30.68	23749301
429	Phosphorylation	QDIRFRSSNDSEESM EECEECCCCCCHHHH	40.16	23749301
432	Phosphorylation	RFRSSNDSEESMQRV EECCCCCCHHHHHHH	47.73	23749301
435	Phosphorylation	SSNDSEESMQRVIKP CCCCCHHHHHHHHCC	19.03	23749301
443	Phosphorylation	MQRVIKPSSALQF-- HHHHHCCHHHCCC--	24.20	22369663
444	Phosphorylation	QRVIKPSSALQF--- HHHHCCHHHCCC---	41.34	22369663

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ECM7_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ECM7_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ECM7_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BRE1_YEAST	BRE1	genetic	27708008
TPS2_YEAST	TPS2	genetic	27708008
KPC1_YEAST	PKC1	genetic	27708008
CALM_YEAST	CMD1	genetic	27708008
RPAB1_YEAST	RPB5	genetic	27708008
KIN28_YEAST	KIN28	genetic	27708008
RPB1_YEAST	RPO21	genetic	27708008
GPI10_YEAST	GPI10	genetic	27708008
MIF2_YEAST	MIF2	genetic	27708008
ERG27_YEAST	ERG27	genetic	27708008
RU1C_YEAST	YHC1	genetic	27708008
SEC23_YEAST	SEC23	genetic	27708008
ACK1_YEAST	ACK1	genetic	27708008
OST4_YEAST	OST4	genetic	27708008
MNN10_YEAST	MNN10	genetic	27708008
PMP3_YEAST	PMP3	genetic	27708008
RV167_YEAST	RVS167	genetic	27708008
BLM10_YEAST	BLM10	genetic	27708008
RIM15_YEAST	RIM15	genetic	27708008
AAKG_YEAST	SNF4	genetic	27708008
PEF1_YEAST	PEF1	genetic	27708008
PRY1_YEAST	PRY1	genetic	27708008
IF4A_YEAST	TIF2	genetic	27708008
CSN12_YEAST	YJR084W	genetic	27708008
METK1_YEAST	SAM1	genetic	27708008
MMR1_YEAST	MMR1	genetic	27708008
YNB1_YEAST	YNL011C	genetic	27708008
SIN3_YEAST	SIN3	genetic	27708008
SIL1_YEAST	SIL1	genetic	27708008
INO4_YEAST	INO4	genetic	27708008
GGPPS_YEAST	BTS1	genetic	27708008
SRO7_YEAST	SRO7	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.