dbPTM

LOH1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	LOH1_YEAST
UniProt AC	P47055
Protein Name	Outer spore wall protein 4 {ECO:0000303\|PubMed:19779569}
Gene Name	LOH1 {ECO:0000303\|PubMed:18562670}
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	219
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description	Involved in spore wall assembly. [PubMed: 23966878 May be involved in maintaining genome integrity]
Protein Sequence	MRFQLFIYFYFTIVVIAGTNTIQQFSDAGDRLITSLRNLDNNGTYETLTAEKVPIIEGQIQNISAKYEQHTFILKGLEAVLNYKVKSLDNNERESLEIEYEKVEKALDAALNVSPFEYIKKFKEVSRGKVVNALENLSREQNRITINGGREDEKEKEAREKKKRLDRIKRILTVSLLELGLAQGVADLCAVAPFACLLGVTVGSIGFIFWLALIYNAIQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
42	N-linked_Glycosylation	SLRNLDNNGTYETLT HEECCCCCCCEEEEE	43.80	-
62	N-linked_Glycosylation	IIEGQIQNISAKYEQ EEEEEEEECHHEECC	31.63	-
136	N-linked_Glycosylation	KVVNALENLSREQNR HHHHHHHHHCHHHCC	44.13	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of LOH1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of LOH1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of LOH1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MRX3_YEAST	YBL095W	genetic	27708008
MRM2_YEAST	MRM2	genetic	27708008
INO4_YEAST	INO4	genetic	27708008
NCBP2_YEAST	CBC2	genetic	27708008
NPL4_YEAST	NPL4	genetic	27708008
SGF73_YEAST	SGF73	genetic	27708008
NNK1_YEAST	NNK1	genetic	27708008
PPQ1_YEAST	PPQ1	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of LOH1_YEAST

Related Literatures of Post-Translational Modification