MFAL1_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MFAL1_YEAST
• UniProt AC: P01149
• Protein Name: Mating factor alpha-1
• Gene Name: MF(ALPHA)1
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 165
• Protein Description: The active factor is excreted into the culture medium by haploid cells of the alpha mating type and acts on cells of the opposite mating type (type A). It mediates the conjugation process between the two types by inhibiting the initiation of DNA synthesis in type a cells and synchronizing them with type alpha..
• Protein Sequence: MRFPSIFTAVLFAASSALAAPVNTTTEDETAQIPAEAVIGYLDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLDKREAEAWHWLQLKPGQPMYKREAEAEAWHWLQLKPGQPMYKREADAEAWHWLQLKPGQPMYKREADAEAWHWLQLKPGQPMY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
138	Ubiquitination	AWHWLQLKPGQPMYK HHHHHCCCCCCCCCC	33.85	24961812
159	Ubiquitination	AWHWLQLKPGQPMY- HHHHHCCCCCCCCC-	33.85	24961812

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MFAL1_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MFAL1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MFAL1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
STE2_YEAST	STE2	physical	2846561

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.