| UniProt ID | SEC11_YEAST | |
|---|---|---|
| UniProt AC | P15367 | |
| Protein Name | Signal peptidase complex catalytic subunit SEC11 | |
| Gene Name | SEC11 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 167 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Single-pass type II membrane protein . |
|
| Protein Description | Catalytic component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum.. | |
| Protein Sequence | MNLRFELQKLLNVCFLFASAYMFWQGLAIATNSASPIVVVLSGSMEPAFQRGDILFLWNRNTFNQVGDVVVYEVEGKQIPIVHRVLRQHNNHADKQFLLTKGDNNAGNDISLYANKKIYLNKSKEIVGTVKGYFPQLGYITIWISENKYAKFALLGMLGLSALLGGE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 77 | Ubiquitination | VVYEVEGKQIPIVHR EEEEECCEECCHHHH | 31.39 | 23749301 | |
| 101 | Ubiquitination | DKQFLLTKGDNNAGN CCEEEEECCCCCCCC | 65.32 | 24961812 | |
| 116 | Ubiquitination | DISLYANKKIYLNKS CEEEEECCEEEECCC | 32.17 | 22817900 | |
| 117 | Ubiquitination | ISLYANKKIYLNKSK EEEEECCEEEECCCC | 36.07 | 22817900 | |
| 121 | N-linked_Glycosylation | ANKKIYLNKSKEIVG ECCEEEECCCCHHEE | 29.59 | - | |
| 122 | Ubiquitination | NKKIYLNKSKEIVGT CCEEEECCCCHHEEE | 61.38 | 22817900 | |
| 149 | Phosphorylation | IWISENKYAKFALLG EEEECCHHHHHHHHH | 26.97 | 28889911 | |
| 161 | Phosphorylation | LLGMLGLSALLGGE- HHHHHHHHHHHCCC- | 18.31 | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SEC11_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SEC11_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SEC11_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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