DIN7_YEAST - dbPTM
DIN7_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID DIN7_YEAST
UniProt AC Q12086
Protein Name DNA damage-inducible protein DIN7
Gene Name DIN7
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 430
Subcellular Localization Nucleus .
Protein Description 5'->3' double-stranded DNA exonuclease..
Protein Sequence MGIPGLLPQLKRIQKQVSLKKYMYQTLAIDGYAWLHRASCACAFELVMNKPTNKYLQFFIKRLQLLKRLKIKPYIVFDGDSLFVKNHTETRRRKKRLENEMIAKKLWSAGNRYNAMEYFQKSVDITPEMAKCIIDYCKLHSIPYIVAPFEADPQMVYLEKMGLIQGIISEDSDLLVFGCKTLITKLNDQGKALEISKDDFSALPENFPLGELSEQQFRNLVCLAGCDYTSGIWKVGVVTAMKIVKRYSEMKDILIQIERTEKLCFSKAFKQQVEFANYAFQYQRVFCPLSNQITTLNNIPKAVTNSHAEIIKIMKCIGSVVERGSGVRKDVINTKNIDHKVHEMIAKGELHPVDMASKLINRERKLKARKLFKVGLLGGESNSFNKKVEQPLVDTQDVLSERENSLDNKNASSIYMTSPAAISGTVPSIF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
412PhosphorylationSLDNKNASSIYMTSP
CCCCCCCCCCEECCH
27.0222890988
413PhosphorylationLDNKNASSIYMTSPA
CCCCCCCCCEECCHH
18.4822890988
415PhosphorylationNKNASSIYMTSPAAI
CCCCCCCEECCHHHH
9.0422890988
417PhosphorylationNASSIYMTSPAAISG
CCCCCEECCHHHHCC
18.0022890988
418PhosphorylationASSIYMTSPAAISGT
CCCCEECCHHHHCCC
8.9422890988
423PhosphorylationMTSPAAISGTVPSIF
ECCHHHHCCCCCCCC
24.5522890988
425PhosphorylationSPAAISGTVPSIF--
CHHHHCCCCCCCC--
23.5822890988
428PhosphorylationAISGTVPSIF-----
HHCCCCCCCC-----
32.0822890988

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of DIN7_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of DIN7_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of DIN7_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SWD3_YEASTSWD3genetic
17314980
SAC3_YEASTSAC3genetic
17314980
SYIC_YEASTILS1genetic
27708008
KRR1_YEASTKRR1genetic
27708008
CDC10_YEASTCDC10genetic
27708008
MOB2_YEASTMOB2genetic
27708008
PRP21_YEASTPRP21genetic
27708008
SEC22_YEASTSEC22genetic
27708008
ESA1_YEASTESA1genetic
27708008
FEN1_YEASTRAD27genetic
28678842

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of DIN7_YEAST

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Related Literatures of Post-Translational Modification

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