VTC1_YEAST - dbPTM
VTC1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID VTC1_YEAST
UniProt AC P40046
Protein Name Vacuolar transporter chaperone 1
Gene Name VTC1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 129
Subcellular Localization Vacuole membrane
Multi-pass membrane protein .
Protein Description Component of the vacuolar transporter chaperone (VTC) complex, which plays a role in vacuolar membrane fusion. Required for SEC18/NSF activity in SNARE priming, membrane binding of LMA1 and V(0) trans-complex formation..
Protein Sequence MSSAPLLQRTPGKKIALPTRVEPKVFFANERTFLSWLNFTVMLGGLGVGLLNFGDKIGRVSAGLFTFVAMGTMIYALVTYHWRAAAIRRRGSGPYDDRLGPTLLCFFLLVAVIINFILRLKYNDANTKL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MSSAPLLQR
------CCCCCCCCC		34.9022814378
2Phosphorylation------MSSAPLLQR
------CCCCCCCCC		34.9022369663
3Phosphorylation-----MSSAPLLQRT
-----CCCCCCCCCC		32.3822369663
10PhosphorylationSAPLLQRTPGKKIAL
CCCCCCCCCCCCEEC		24.3528152593
24UbiquitinationLPTRVEPKVFFANER
CCCCCCCEEEECCCH		37.8624961812
24AcetylationLPTRVEPKVFFANER
CCCCCCCEEEECCCH		37.8624489116
24SuccinylationLPTRVEPKVFFANER
CCCCCCCEEEECCCH		37.8623954790
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of VTC1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of VTC1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of VTC1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
VTC3_YEASTVTC3physical
11823419
VTC4_YEASTVTC4physical
11823419
VTC2_YEASTVTC2physical
11823419
VPS8_YEASTVPS8genetic
20093466
YAJ9_YEASTYAR029Wgenetic
20093466
OSH1_YEASTSWH1genetic
20093466
SFT2_YEASTSFT2genetic
20093466
HEK2_YEASTHEK2genetic
20093466
DSF2_YEASTDSF2genetic
20093466
ETR1_YEASTETR1genetic
20093466
YBP1_YEASTYBP1genetic
20093466
ODPB_YEASTPDB1genetic
20093466
CHK1_YEASTCHK1genetic
20093466
YB9Z_YEASTYBR284Wgenetic
20093466
YB8B_YEASTYBR287Wgenetic
20093466
BSD2_YEASTBSD2genetic
20093466
ATG22_YEASTATG22genetic
20093466
RBSK_YEASTRBK1genetic
20093466
YCZ2_YEASTYCR102Cgenetic
20093466
ADY3_YEASTADY3genetic
20093466
WHI4_YEASTWHI4genetic
20093466
DTD_YEASTDTD1genetic
20093466
ASF2_YEASTASF2genetic
20093466
UFD2_YEASTUFD2genetic
20093466
RLA3_YEASTRPP1Bgenetic
20093466
RS16A_YEASTRPS16Bgenetic
20093466
RS16B_YEASTRPS16Bgenetic
20093466
RLA1_YEASTRPP1Agenetic
20093466
MTU1_YEASTSLM3genetic
20093466
RMD1_YEASTRMD1genetic
20093466
VMS1_YEASTVMS1genetic
20093466
TGL2_YEASTTGL2genetic
20093466
EBS1_YEASTEBS1genetic
20093466
MNN10_YEASTMNN10genetic
20093466
IPK1_YEASTIPK1genetic
20093466
DFM1_YEASTDFM1genetic
20093466
ERD1_YEASTERD1genetic
20093466
RSM28_YEASTRSM28genetic
20093466
RAD4_YEASTRAD4genetic
20093466
YGY0_YEASTYGL230Cgenetic
20093466
ATC1_YEASTPMR1genetic
20093466
AAKG_YEASTSNF4genetic
20093466
CGR1_YEASTCGR1genetic
20093466
FKS2_YEASTGSC2genetic
20093466
XKS1_YEASTXKS1genetic
20093466
MGA1_YEASTMGA1genetic
20093466
TNA1_YEASTTNA1genetic
20093466
MAL12_YEASTMAL12genetic
20093466
AIM18_YEASTAIM18genetic
20093466
BAR1_YEASTBAR1genetic
20093466
YJQ3_YEASTYJL163Cgenetic
20093466
RS21B_YEASTRPS21Bgenetic
20093466
MTC1_YEASTMTC1genetic
20093466
MOG1_YEASTMOG1genetic
20093466
DBP7_YEASTDBP7genetic
20093466
SWI6_YEASTSWI6genetic
20093466
YL422_YEASTYLR422Wgenetic
20093466
VPS9_YEASTVPS9genetic
20093466
MSS1_YEASTMSS1genetic
20093466
YAP4_YEASTCIN5genetic
20093466
THI21_YEASTTHI21genetic
20093466
PPQ1_YEASTPPQ1genetic
20093466
ELP4_YEASTELP4genetic
20093466
GET2_YEASTGET2genetic
19325107
DED1_YEASTDED1physical
22940862
G3P3_YEASTTDH3physical
22940862
NOP14_YEASTNOP14physical
22940862
PMA1_YEASTPMA1physical
22940862
KPYK1_YEASTCDC19physical
22940862
CHK1_YEASTCHK1genetic
22282571
MOB2_YEASTMOB2genetic
27708008
CDC24_YEASTCDC24genetic
27708008
CDC4_YEASTCDC4genetic
27708008
GNA1_YEASTGNA1genetic
27708008
SMD1_YEASTSMD1genetic
27708008
MET30_YEASTMET30genetic
27708008
SEC22_YEASTSEC22genetic
27708008
SEN1_YEASTSEN1genetic
27708008
GPI12_YEASTGPI12genetic
27708008
RPB2_YEASTRPB2genetic
27708008
GPN2_YEASTGPN2genetic
27708008
PSB5_YEASTPRE2genetic
27708008
VPS8_YEASTVPS8genetic
27708008
TGL2_YEASTTGL2genetic
27708008
ATC1_YEASTPMR1genetic
27708008
HUR1_YEASTHUR1genetic
27708008
MLH1_YEASTMLH1genetic
27708008
INO4_YEASTINO4genetic
27708008
YD089_YEASTYDR089Wphysical
27587415
NYV1_YEASTNYV1genetic
27252384
PHO80_YEASTPHO80genetic
27252384
RFA1_YEASTRFA1genetic
29674565
STU1_YEASTSTU1genetic
29674565
MRC1_YEASTMRC1genetic
29674565
DAD1_YEASTDAD1genetic
29674565
DPOD3_YEASTPOL32genetic
29674565
CDC11_YEASTCDC11genetic
29674565
AP1S1_YEASTAPS1genetic
29674565
NMT_YEASTNMT1genetic
29674565
UTP13_YEASTUTP13genetic
29674565
CSM3_YEASTCSM3genetic
29674565
MYO2_YEASTMYO2genetic
29674565
AP1G1_YEASTAPL4genetic
29674565
RIC1_YEASTRIC1genetic
29674565
TRS20_YEASTTRS20genetic
29674565
THRC_YEASTTHR4genetic
29674565
YG36_YEASTYGR126Wgenetic
29674565
PNT1_YEASTPNT1genetic
29674565
RU2A_YEASTLEA1genetic
29674565
NEW1_YEASTNEW1genetic
29674565
KAR3_YEASTKAR3genetic
29674565
CKS1_YEASTCKS1genetic
29674565
SWC5_YEASTSWC5genetic
29674565
HCM1_YEASTHCM1genetic
29674565
ATG15_YEASTATG15genetic
29674565
SYF2_YEASTSYF2genetic
29674565
ARP4_YEASTARP4genetic
29674565
RS21B_YEASTRPS21Bgenetic
29674565
ERG2_YEASTERG2genetic
29674565
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of VTC1_YEAST

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Related Literatures of Post-Translational Modification

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