| UniProt ID | ARPC4_YEAST | |
|---|---|---|
| UniProt AC | P33204 | |
| Protein Name | Actin-related protein 2/3 complex subunit 4 | |
| Gene Name | ARC19 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 171 | |
| Subcellular Localization | Cytoplasm, cytoskeleton, actin patch. | |
| Protein Description | Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity).. | |
| Protein Sequence | MSQSLRPYLTAVRYSLEAALTLSNFSSQEVERHNRPEVEVPNTSAELLLQPMHISRNENEQVLIEPSVNSVRMSLMVKQADEIEQILVHKFTRFLEQRAEAFYILRRVPIPGYSISFLITNKHTESMKTGKLVDFIIEFMEDVDKEISEIKLFLNARARFVAEAYLDEFVY | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSQSLRPYL ------CCCCCHHHH | 28.60 | 22369663 | |
| 4 | Phosphorylation | ----MSQSLRPYLTA ----CCCCCHHHHHH | 21.02 | 22369663 | |
| 90 | Acetylation | IEQILVHKFTRFLEQ HHHHHHHHHHHHHHH | 40.74 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ARPC4_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ARPC4_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ARPC4_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MYO3_YEAST | MYO3 | physical | 10648568 | |
| MYO5_YEAST | MYO5 | physical | 10648568 | |
| ARPC5_YEAST | ARC15 | physical | 11283351 | |
| ARPC3_YEAST | ARC18 | physical | 18467557 | |
| LAS17_YEAST | LAS17 | physical | 18467557 | |
| CAP_YEAST | SRV2 | physical | 18467557 | |
| SLA2_YEAST | SLA2 | physical | 18467557 | |
| VRP1_YEAST | VRP1 | physical | 18467557 | |
| HUG1_YEAST | HUG1 | physical | 18467557 | |
| ARPC2_YEAST | ARC35 | physical | 18467557 | |
| ARPC3_YEAST | ARC18 | physical | 22615397 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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