HUG1_YEAST - dbPTM
HUG1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HUG1_YEAST
UniProt AC Q6Q5K6
Protein Name MEC1-mediated checkpoint protein HUG1
Gene Name HUG1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 68
Subcellular Localization Cytoplasm . Nucleus .
Protein Description Involved in the MEC1-mediated checkpoint response to DNA damage and replication arrest..
Protein Sequence MTMDQGLNPKQFFLDDVVLQDTLCSMSNRVNKSVKTGYLFPKDHVPSANIIAVERRGGLSDIGKNTSN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
60PhosphorylationVERRGGLSDIGKNTS
EEECCCCCCCCCCCC
30.3827017623

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of HUG1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HUG1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HUG1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PGM2_YEASTPGM2physical
18467557
SLA2_YEASTSLA2physical
18467557
SKI3_YEASTSKI3physical
18467557
ALO_YEASTALO1physical
18467557
PUR92_YEASTADE17physical
18467557
PGM2_YEASTPGM2physical
22615397
RIR2_YEASTRNR2physical
25378334
DNA2_YEASTDNA2physical
25378334
RIR4_YEASTRNR4physical
25378334
APC11_YEASTAPC11genetic
27708008
PDC2_YEASTPDC2genetic
27708008
GNA1_YEASTGNA1genetic
27708008
FDFT_YEASTERG9genetic
27708008
YJ9I_YEASTYJR141Wgenetic
27708008
RU1C_YEASTYHC1genetic
27708008
SC61A_YEASTSEC61genetic
27708008
SMP3_YEASTSMP3genetic
27708008
DYR_YEASTDFR1genetic
27708008
HRR25_YEASTHRR25genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HUG1_YEAST

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Related Literatures of Post-Translational Modification

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