| UniProt ID | ATF1_YEAST | |
|---|---|---|
| UniProt AC | P40353 | |
| Protein Name | Alcohol O-acetyltransferase 1 {ECO:0000303|PubMed:8085822} | |
| Gene Name | ATF1 {ECO:0000303|PubMed:8085822} | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 525 | |
| Subcellular Localization |
Lipid droplet . Endoplasmic reticulum membrane Peripheral membrane protein . Traffics to lipid droplets during the stationary phase (PubMed:25093817). |
|
| Protein Description | Major alcohol O-acetyltransferase that uses acetyl-CoA to synthesize acetate esters from various alcohols, producing ethyl acetate, isoamyl acetate, isobutyl acetate, butyl acetate, hexyl acetate, heptyl acetate and octyl acetate. [PubMed: 7764365] | |
| Protein Sequence | MNEIDEKNQAPVQQECLKEMIQNGHARRMGSVEDLYVALNRQNLYRNFCTYGELSDYCTRDQLTLALREICLKNPTLLHIVLPTRWPNHENYYRSSEYYSRPHPVHDYISVLQELKLSGVVLNEQPEYSAVMKQILEEFKNSKGSYTAKIFKLTTTLTIPYFGPTGPSWRLICLPEEHTEKWKKFIFVSNHCMSDGRSSIHFFHDLRDELNNIKTPPKKLDYIFKYEEDYQLLRKLPEPIEKVIDFRPPYLFIPKSLLSGFIYNHLRFSSKGVCMRMDDVEKTDDVVTEIINISPTEFQAIKANIKSNIQGKCTITPFLHVCWFVSLHKWGKFFKPLNFEWLTDIFIPADCRSQLPDDDEMRQMYRYGANVGFIDFTPWISEFDMNDNKENFWPLIEHYHEVISEALRNKKHLHGLGFNIQGFVQKYVNIDKVMCDRAIGKRRGGTLLSNVGLFNQLEEPDAKYSICDLAFGQFQGSWHQAFSLGVCSTNVKGMNIVVASTKNVVGSQESLEELCSIYKALLLGP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 7 | Ubiquitination | -MNEIDEKNQAPVQQ -CCCHHHHCCHHHHH | 51.08 | 24961812 | |
| 31 | Phosphorylation | GHARRMGSVEDLYVA CCHHHCCCHHHHHHH | 17.00 | 28889911 | |
| 36 | Phosphorylation | MGSVEDLYVALNRQN CCCHHHHHHHHHHCC | 8.94 | 28889911 | |
| 283 | Phosphorylation | RMDDVEKTDDVVTEI CCHHCCCCCCHHHEE | 24.75 | 29688323 | |
| 288 | Phosphorylation | EKTDDVVTEIINISP CCCCCHHHEEECCCH | 22.70 | 29688323 | |
| 294 | Phosphorylation | VTEIINISPTEFQAI HHEEECCCHHHHHHH | 22.68 | 29688323 | |
| 296 | Phosphorylation | EIINISPTEFQAIKA EEECCCHHHHHHHHH | 42.51 | 29688323 | |
| 365 | Phosphorylation | DDEMRQMYRYGANVG HHHHHHHHHHCCCEE | 7.73 | 19779198 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ATF1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ATF1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ATF1_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ATF2_YEAST | ATF2 | genetic | 12957907 | |
| PMT4_YEAST | PMT4 | genetic | 16269340 | |
| PEX29_YEAST | PEX29 | physical | 18719252 | |
| SLI1_YEAST | SLI1 | genetic | 19270382 | |
| LEUC_YEAST | LEU1 | genetic | 19270382 | |
| LEU3_YEAST | LEU2 | genetic | 19270382 | |
| LEU1_YEAST | LEU4 | genetic | 19270382 | |
| ACON2_YEAST | ACO2 | genetic | 21623372 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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