GTT3_YEAST - dbPTM
GTT3_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GTT3_YEAST
UniProt AC P39996
Protein Name Glutathione transferase 3
Gene Name GTT3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 337
Subcellular Localization Nucleus membrane
Multi-pass membrane protein .
Protein Description
Protein Sequence MPTKSTFSRWKKADLIDLANKLEIDGFPNYAKKSDMIDYLESHLNHLEKPVDFKDDYPELRSFYESMTVDQSKDERNEYGSGSGNGSGSGSCDTATNDSDLEKAYIKEDDDEKPQSGDETSATKPLSSRNANSNAKTNFNLLDFSTDNDSSTSAFTKFKFNFQEYLSDIRYQTQKLNENVQDYLSTISAVDTIFSLLEFSFLVRNILAAGQPTSSSSLASSLEAAVAAHNKYQYTLDFCLPILTWLLFFRGIPTLVSYYINFIRYDLNIELDPMTFNLTKFLISLAIFKTCNNKNIDFHSFRCVNQLWTQLCTVNRSLGMVPLVFSMVSCLLTLYVL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
62PhosphorylationDDYPELRSFYESMTV
CCCHHHHHHHHHCCC		44.8220377248
64PhosphorylationYPELRSFYESMTVDQ
CHHHHHHHHHCCCCC		14.3519779198
66PhosphorylationELRSFYESMTVDQSK
HHHHHHHHCCCCCCC		14.3628889911
68PhosphorylationRSFYESMTVDQSKDE
HHHHHHCCCCCCCCC		30.1519779198
72PhosphorylationESMTVDQSKDERNEY
HHCCCCCCCCCCCCC		37.3028889911
79PhosphorylationSKDERNEYGSGSGNG
CCCCCCCCCCCCCCC		21.8219823750
81PhosphorylationDERNEYGSGSGNGSG
CCCCCCCCCCCCCCC		28.9619823750
83PhosphorylationRNEYGSGSGNGSGSG
CCCCCCCCCCCCCCC		30.6829136822
87PhosphorylationGSGSGNGSGSGSCDT
CCCCCCCCCCCCCCC		33.5121551504
89PhosphorylationGSGNGSGSGSCDTAT
CCCCCCCCCCCCCCC		29.2729136822
91PhosphorylationGNGSGSGSCDTATND
CCCCCCCCCCCCCCC		15.5419823750
94PhosphorylationSGSGSCDTATNDSDL
CCCCCCCCCCCCHHH		39.4421551504
96PhosphorylationSGSCDTATNDSDLEK
CCCCCCCCCCHHHHH		41.4729136822
99PhosphorylationCDTATNDSDLEKAYI
CCCCCCCHHHHHHHC		46.2819823750
116PhosphorylationDDDEKPQSGDETSAT
CCCCCCCCCCCCCCC		57.6622369663
120PhosphorylationKPQSGDETSATKPLS
CCCCCCCCCCCCCCC		28.5322369663
121PhosphorylationPQSGDETSATKPLSS
CCCCCCCCCCCCCCC		31.7120377248
123PhosphorylationSGDETSATKPLSSRN
CCCCCCCCCCCCCCC		32.7222369663
127PhosphorylationTSATKPLSSRNANSN
CCCCCCCCCCCCCCC		35.4622369663
128PhosphorylationSATKPLSSRNANSNA
CCCCCCCCCCCCCCC		36.9222369663
133PhosphorylationLSSRNANSNAKTNFN
CCCCCCCCCCCCCEE		35.4424961812
145PhosphorylationNFNLLDFSTDNDSST
CEECCCCCCCCCCCC		34.2221551504
146PhosphorylationFNLLDFSTDNDSSTS
EECCCCCCCCCCCCC		38.5230377154
150PhosphorylationDFSTDNDSSTSAFTK
CCCCCCCCCCCCCHH		41.5921440633
151PhosphorylationFSTDNDSSTSAFTKF
CCCCCCCCCCCCHHE		29.2825521595
152PhosphorylationSTDNDSSTSAFTKFK
CCCCCCCCCCCHHEE		28.2027214570
153PhosphorylationTDNDSSTSAFTKFKF
CCCCCCCCCCHHEEE		24.2730377154
284PhosphorylationNLTKFLISLAIFKTC
HHHHHHHHHHHHHHC		17.5619795423
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GTT3_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GTT3_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GTT3_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GTT3_YEASTGTT3physical
11283351
GTT3_YEASTGTT3physical
18467557
RS6A_YEASTRPS6Bgenetic
27708008
RS6B_YEASTRPS6Bgenetic
27708008
CS111_YEASTCOS111genetic
27708008
MED20_YEASTSRB2genetic
27708008
PALI_YEASTRIM9genetic
27708008
BUD21_YEASTBUD21genetic
27708008
MDL2_YEASTMDL2genetic
27708008
GEM1_YEASTGEM1genetic
27708008
BMT2_YEASTBMT2genetic
27708008
SGF29_YEASTSGF29genetic
27708008
ELO2_YEASTELO2genetic
27708008
YD012_YEASTYDL012Cgenetic
27708008
BRE1_YEASTBRE1genetic
27708008
VMA21_YEASTVMA21genetic
27708008
NKP2_YEASTNKP2genetic
27708008
SCS7_YEASTSCS7genetic
27708008
SIN3_YEASTSIN3genetic
27708008
ALDH6_YEASTALD6genetic
27708008
TBP6_YEASTYTA6genetic
27708008
WDR6_YEASTRTT10genetic
27708008
CGAT2_HUMANCSGALNACT2physical
27107014
KASH5_HUMANCCDC155physical
27107014
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GTT3_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases.";
Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.;
Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-116, AND MASSSPECTROMETRY.
"Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae.";
Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.;
J. Proteome Res. 6:1190-1197(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-116, AND MASSSPECTROMETRY.

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