YMH9_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YMH9_YEAST
• UniProt AC: Q03629
• Protein Name: Uncharacterized protein YML079W
• Gene Name: YML079W
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 201
• Protein Sequence: MSANVQEAANAAIEPASFVKVPMPEPPSSLQQLINDWQLIKHREGGYFKETDRSPYTMEVEKPVNGGSGNTEMVTRNQSTLIYYLLTPDSPIGKFHKNINRIIHILQRGKGQYVLVYPDGQVKSFKVGFDYKNGEVSQWVVPGGVFKASFLLPNEEFDNGFLISEVVVPGFDFEDHTFLKGEDELKHLVGPEKAAELAFLA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSANVQEAA ------CCHHHHHHH	28.66	24909858
17	Phosphorylation	NAAIEPASFVKVPMP HHHCCCCCEEECCCC	41.09	24909858
68	Phosphorylation	EKPVNGGSGNTEMVT EECCCCCCCCCEEEE	30.21	28889911
90	Phosphorylation	YYLLTPDSPIGKFHK EEEECCCCCCHHHHH	21.44	28889911
110	Ubiquitination	IHILQRGKGQYVLVY HHHHHCCCCEEEEEE	45.06	24961812
113	Phosphorylation	LQRGKGQYVLVYPDG HHCCCCEEEEEECCC	12.38	19779198
117	Phosphorylation	KGQYVLVYPDGQVKS CCEEEEEECCCCEEE	7.46	19779198
186	Acetylation	LKGEDELKHLVGPEK ECCHHHHHHHHCHHH	32.61	24489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YMH9_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YMH9_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YMH9_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YMH9_YEAST	YML079W	physical	15608122
YMH9_YEAST	YML079W	physical	18719252
RPB1_YEAST	RPO21	genetic	27708008
TAF12_YEAST	TAF12	genetic	27708008
ACT_YEAST	ACT1	genetic	27708008
PRP43_YEAST	PRP43	genetic	27708008
SMD1_YEAST	SMD1	genetic	27708008
NOP2_YEAST	NOP2	genetic	27708008
RPB2_YEAST	RPB2	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-68 AND SER-90, AND MASSSPECTROMETRY.
PubMed: 18407956