YD131_YEAST - dbPTM
YD131_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID YD131_YEAST
UniProt AC Q03899
Protein Name F-box protein YDR131C
Gene Name YDR131C
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 556
Subcellular Localization Vacuole .
Protein Description Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins (By similarity)..
Protein Sequence MFDKLPYEIFKQIAWRIPQEDKISLTYVCKRSYESIIPFIYQNLFLNETYHINGDYDNSFGTCYWSVLNFHYIDEDDSNTKNDMSNRRLAKVKFSYFERTLAESPKRLCPLINRIRCTWHLNEDVMTNVLKLLSEYGSNLKFVDQFVRSSVNKGLEPLSKQLKTLTLTPPTLMPTHNSVSGSYLNKIDRLLLKCDLSRLEKLSIHINALKYFKNTGSPMKIKALVLNLRPDTLNLAEYDASDDFLKELEYIDIFDASTLRQLEILSWYSRDDFPSGEEGGFDRLYVKWGLEGFWKFPNIEKLSLASLVYSEFFLMNCLAVFHNLKILKLDYMGKFDFDVSLINFLSKQVCGKKLQRFDIHCQLNHRLFFPMTDNPLTRLNFDGFCPCSTCKNTIHEVILKKIFPETRSKLLKNPNKFQAHNFFYQMFFENKIMPYTNIIDNESPAMGWDSVPIETFVRKFNENLQSTIENTENITVNKITREDAISLYHLYLHYLKDVFKVFEQSLPNLEYLTINGIPTKIIQVDELQRCAVPLFYNNGYKSNSVYELVDAEALFS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
168PhosphorylationQLKTLTLTPPTLMPT
HHCCEEECCCCCCCC		23.2219779198
171PhosphorylationTLTLTPPTLMPTHNS
CEEECCCCCCCCCCC		36.5719779198
175PhosphorylationTPPTLMPTHNSVSGS
CCCCCCCCCCCCCHH		21.5227017623
180PhosphorylationMPTHNSVSGSYLNKI
CCCCCCCCHHHHHHH		23.1119779198
183PhosphorylationHNSVSGSYLNKIDRL
CCCCCHHHHHHHHHH		20.1627017623
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of YD131_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of YD131_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of YD131_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SKP1_YEASTSKP1physical
11805837
YRB2_YEASTYRB2physical
11805837
LAG2_YEASTLAG2physical
19763088
SPI1_YEASTSPI1genetic
20093466
TFS2_YEASTDST1genetic
20093466
FRMSR_YEASTYKL069Wgenetic
20093466
SPH1_YEASTSPH1genetic
20093466
HXT2_YEASTHXT2genetic
20093466
RTG1_YEASTRTG1genetic
20093466
YO08A_YEASTYOR008C-Agenetic
20093466
YME1_YEASTYME1genetic
20093466
EDS1_YEASTEDS1genetic
27708008
MSH3_YEASTMSH3genetic
27708008
PEX19_YEASTPEX19genetic
27708008
RV167_YEASTRVS167genetic
27708008
SPI1_YEASTSPI1genetic
27708008
UBP3_YEASTUBP3genetic
27708008
TFS2_YEASTDST1genetic
27708008
BUB1_YEASTBUB1genetic
27708008
DAL81_YEASTDAL81genetic
27708008
ISY1_YEASTISY1genetic
27708008
FRMSR_YEASTYKL069Wgenetic
27708008
SYM1_YEASTSYM1genetic
27708008
SPH1_YEASTSPH1genetic
27708008
CDC73_YEASTCDC73genetic
27708008
UBP8_YEASTUBP8genetic
27708008
RTG1_YEASTRTG1genetic
27708008
IRA2_YEASTIRA2genetic
27708008
YO08A_YEASTYOR008C-Agenetic
27708008
SFM1_YEASTSFM1genetic
27708008
HSP7F_YEASTSSE1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of YD131_YEAST

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Related Literatures of Post-Translational Modification

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