EDS1_YEAST - dbPTM
EDS1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID EDS1_YEAST
UniProt AC P38073
Protein Name Transcriptional regulatory protein EDS1
Gene Name EDS1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 919
Subcellular Localization Nucleus .
Protein Description
Protein Sequence MSHHVPNLYGTPIRDPHERKRNSASMGEVNQSVSSRNCERGSEKGTKQRKKASHACDQCRRKRIKCRFDKHTGVCQGCLEVGEKCQFIRVPLKRGPAKKRGSVVSIEKFSSDNDPLQYRPRTHSYPMNSGNNYLPSLARNSSFPSISSLFVPSITAQSQQFVKVPYDDIKRRSSLAILGSDSSISTEFGGNYRLDENLNVRQEGKDIVAKGMITPVEEMGACSSNVRRQGSQSLPIQEQRASPYINPFISGRSRLSSLSYTSEATTSEGNTQGKNQCMLTPNSVRSIEKERLNSLTAGFPNKKLGTDGRSDKWDKNSTWKPVYRSSNPSHPSTEKNVSLNQEASAKPLMLGTYRQFDATSFYKVLGIYYNFFHINFPVIPINKSKFTDMLDPEKPNVIDEIRQINNEIIQCFKTALEVLVFCKIKQRRSSKSTKSWSRDSLCDFQKGLYYIQNFNKCIADCFQSLITIKPVLKQNSSVIPSRIKFIYFSTIIVLNFILILAGEESSLLLGPSVGVFNEFQAHKLFLPFQNTSPMLLLNSNEESGDEILDYAVLFKRLYILLNILDTLQSFRLGQPKLINLNFGSAIETYFSDKTGHNQVVEKAPVALDNILRNLKLGEFITYFVLNRKSLQVNVPHHLLFTNQTDYGEFAVEKGEHDNIAGKFETLLKKKEILIRKLLNIEQKNDHILENCCNSDAEMKNIGELVCSMITLVSGILDSITNMNAENSVDLDSKPLPNAYFAQDSEEELMSPTQSITSNLASEENTRCTTKDLMGTVSIFMLPMVEECYNIISLIGPIPTTLISLYIRNGNMAKGINDRIMTLSTALNELVQITALFNTLEPFRKNAHDRAKRYYVSATSSTGCYESVMKSMYSGKCAASNASNVAPSEEENKKILKKFADIGWKLMDDSELGCCCCFFN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
23PhosphorylationPHERKRNSASMGEVN
HHHHHCCCCCHHHCH		26.2519779198
25PhosphorylationERKRNSASMGEVNQS
HHHCCCCCHHHCHHH		27.4319779198
102PhosphorylationGPAKKRGSVVSIEKF
CCCCCCCCEEEEEEC		24.3128889911
105PhosphorylationKKRGSVVSIEKFSSD
CCCCCEEEEEECCCC		23.9128889911
124PhosphorylationQYRPRTHSYPMNSGN
CCCCCCCCCCCCCCC		30.2519779198
125PhosphorylationYRPRTHSYPMNSGNN
CCCCCCCCCCCCCCC		10.0119779198
231PhosphorylationSNVRRQGSQSLPIQE
CCCCCCCCCCCCCCH		14.3028889911
242PhosphorylationPIQEQRASPYINPFI
CCCHHCCCCCCCCCC		22.0327214570
256PhosphorylationISGRSRLSSLSYTSE
CCCCCCCCCCEEECC		28.2927017623
257PhosphorylationSGRSRLSSLSYTSEA
CCCCCCCCCEEECCC		26.4028132839
271PhosphorylationATTSEGNTQGKNQCM
CCCCCCCCCCCCCEE		49.9427017623
280PhosphorylationGKNQCMLTPNSVRSI
CCCCEEECCCHHHHH		8.1127017623
856PhosphorylationRAKRYYVSATSSTGC
HHHHEEEEECCCCCH		15.0919779198
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of EDS1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of EDS1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of EDS1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SAC3_YEASTSAC3genetic
19547744
PEX22_YEASTPEX22genetic
20093466
SWD1_YEASTSWD1genetic
20093466
YAJ9_YEASTYAR029Wgenetic
20093466
BEM1_YEASTBEM1genetic
20093466
SGF29_YEASTSGF29genetic
20093466
SLX5_YEASTSLX5genetic
20093466
XRS2_YEASTXRS2genetic
20093466
RS17B_YEASTRPS17Bgenetic
20093466
JIP4_YEASTJIP4genetic
20093466
AGE1_YEASTAGE1genetic
20093466
SLX8_YEASTSLX8genetic
20093466
FTHC_YEASTFAU1genetic
20093466
YFD4_YEASTYFL034Wgenetic
20093466
FAR7_YEASTFAR7genetic
20093466
ULI1_YEASTULI1genetic
20093466
AAKG_YEASTSNF4genetic
20093466
MMS2_YEASTMMS2genetic
20093466
RL24A_YEASTRPL24Agenetic
20093466
YG34_YEASTYGR122Wgenetic
20093466
YH10_YEASTYHR210Cgenetic
20093466
IMPX_YEASTIMP2genetic
20093466
PTPA1_YEASTRRD1genetic
20093466
DPH1_YEASTDPH1genetic
20093466
KAPA_YEASTTPK1genetic
20093466
GLG2_YEASTGLG2genetic
20093466
SDHX_YEASTYJL045Wgenetic
20093466
3HAO_YEASTBNA1genetic
20093466
DOHH_YEASTLIA1genetic
20093466
HIR3_YEASTHIR3genetic
20093466
BUD8_YEASTBUD8genetic
20093466
RAD52_YEASTRAD52genetic
20093466
FAR3_YEASTFAR3genetic
20093466
YM8C_YEASTYMR262Wgenetic
20093466
FAR11_YEASTFAR11genetic
20093466
YO08A_YEASTYOR008C-Agenetic
20093466
VPH1_YEASTVPH1genetic
20093466
PALA_YEASTRIM20genetic
20093466
LGE1_YEASTLGE1genetic
20093466
PMA2_YEASTPMA2genetic
20093466
RAD1_YEASTRAD1genetic
20093466
YG2A_YEASTYGR067Cgenetic
20959818
SAC3_YEASTSAC3genetic
20959818
RTG3_YEASTRTG3genetic
21127252
KAPA_YEASTTPK1genetic
22282571
WDR59_YEASTMTC5genetic
27708008
MMS2_YEASTMMS2genetic
27708008
LIPA_YEASTLIP5genetic
27708008
PALA_YEASTRIM20genetic
27708008
PEX22_YEASTPEX22genetic
27708008
SWD1_YEASTSWD1genetic
27708008
SGF29_YEASTSGF29genetic
27708008
FUB1_YEASTFUB1genetic
27708008
MTU1_YEASTSLM3genetic
27708008
GPR1_YEASTGPR1genetic
27708008
RS29B_YEASTRPS29Bgenetic
27708008
RS16A_YEASTRPS16Bgenetic
27708008
RS16B_YEASTRPS16Bgenetic
27708008
SWI5_YEASTSWI5genetic
27708008
CRF1_YEASTCRF1genetic
27708008
LSM6_YEASTLSM6genetic
27708008
RS17B_YEASTRPS17Bgenetic
27708008
BEM2_YEASTBEM2genetic
27708008
FTHC_YEASTFAU1genetic
27708008
FAR7_YEASTFAR7genetic
27708008
RL24A_YEASTRPL24Agenetic
27708008
AAKG_YEASTSNF4genetic
27708008
VMA21_YEASTVMA21genetic
27708008
TIM13_YEASTTIM13genetic
27708008
QCR9_YEASTQCR9genetic
27708008
TBP7_YEASTYTA7genetic
27708008
STB5_YEASTSTB5genetic
27708008
YH10_YEASTYHR210Cgenetic
27708008
DPH1_YEASTDPH1genetic
27708008
IMPX_YEASTIMP2genetic
27708008
SDHX_YEASTYJL045Wgenetic
27708008
KAPA_YEASTTPK1genetic
27708008
3HAO_YEASTBNA1genetic
27708008
DOHH_YEASTLIA1genetic
27708008
RL14A_YEASTRPL14Agenetic
27708008
FEN1_YEASTRAD27genetic
27708008
DPH2_YEASTDPH2genetic
27708008
VPS51_YEASTVPS51genetic
27708008
TVP38_YEASTTVP38genetic
27708008
DNM1_YEASTDNM1genetic
27708008
RL8B_YEASTRPL8Bgenetic
27708008
BRE2_YEASTBRE2genetic
27708008
POM34_YEASTPOM34genetic
27708008
BUD8_YEASTBUD8genetic
27708008
YL422_YEASTYLR422Wgenetic
27708008
RAD52_YEASTRAD52genetic
27708008
FAR3_YEASTFAR3genetic
27708008
CTF18_YEASTCTF18genetic
27708008
SSO2_YEASTSSO2genetic
27708008
YM8C_YEASTYMR262Wgenetic
27708008
RS7B_YEASTRPS7Bgenetic
27708008
FAR11_YEASTFAR11genetic
27708008
SFL1_YEASTSFL1genetic
27708008
VPH1_YEASTVPH1genetic
27708008
FSF1_YEASTFSF1genetic
27708008
RMI1_YEASTRMI1genetic
27708008
PMA2_YEASTPMA2genetic
27708008
LGE1_YEASTLGE1genetic
27708008
MED1_YEASTMED1genetic
27708008
SUE1_YEASTSUE1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of EDS1_YEAST

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Related Literatures of Post-Translational Modification

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