CRF1_YEAST - dbPTM
CRF1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CRF1_YEAST
UniProt AC Q04930
Protein Name Transcription factor CRF1
Gene Name CRF1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 467
Subcellular Localization Cytoplasm . Nucleus . The nuclear location is negatively regulated by the TOR pathway.
Protein Description Transcription factor, corepressor with FHL1 of ribosomal protein genes. May be involved in the blocking of the spread of silencing..
Protein Sequence MLLSAPVNSTVRRKPHSPNKKKPKETGTAASFSSSSSTVVLSSNNDGSFDALWDPSISKASDFESSYISAKRLKPESSNRQKKKNSYKYSREENTNEVEEKTSLGSSSKTEADNIFNDQLTSAGNTTYVSNKRDVNFGANSAVVLLGLPTSKSESHRQYHSPSASTTNEDEEDIGVDILVDNHIDSCETVSINNNRGITHQYPETESDVDFDEAVILTPMDGTDKGVKNPRPLEKKYSSSCFEDRTPLNLDDGHFSECNHFSTLDVSSFFHLNEHVHKIDEVELDGPDRTFSLDNVAINTRKKDIDCLYNSSREDLSNLTCSSEGPRNDSYDSDYNIDEVTYRDDESTDEDESLPTPDRKRKKIGHKACEILDSKRIGIKVPKLYVWSLSDKPFSVIDGLCTKSLYPLSDDINTPESLSSCSSSVSSRENQKGDATFDNDAMIADLLNIGGLEVEKASNGHIELIGE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
71AcetylationESSYISAKRLKPESS
CHHCEECCCCCCCCC		52.0125381059
103PhosphorylationNEVEEKTSLGSSSKT
CCHHHHHCCCCCCCC		41.6327214570
322PhosphorylationDLSNLTCSSEGPRND
HHHCCCCCCCCCCCC		26.6228889911
331PhosphorylationEGPRNDSYDSDYNID
CCCCCCCCCCCCCEE		23.4828889911
333PhosphorylationPRNDSYDSDYNIDEV
CCCCCCCCCCCEEEC		33.4928889911
341PhosphorylationDYNIDEVTYRDDEST
CCCEEECEEECCCCC		15.7028889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CRF1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CRF1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CRF1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RL37A_YEASTRPL37Agenetic
20093466
AVO2_YEASTAVO2genetic
20093466
PHO23_YEASTPHO23genetic
20093466
EOS1_YEASTEOS1genetic
20093466
FHL1_YEASTFHL1physical
27321754
RV161_YEASTRVS161genetic
27708008
RV167_YEASTRVS167genetic
27708008
UBP3_YEASTUBP3genetic
27708008
RL24A_YEASTRPL24Agenetic
27708008
PALF_YEASTRIM8genetic
27708008
EOS1_YEASTEOS1genetic
27708008
YMP0_YEASTYMR010Wgenetic
28057802
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CRF1_YEAST

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Related Literatures of Post-Translational Modification

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