dbPTM

NUP1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NUP1_YEAST
UniProt AC	P20676
Protein Name	Nucleoporin NUP1
Gene Name	NUP1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	1076
Subcellular Localization	Nucleus, nuclear pore complex. Nucleus membrane Peripheral membrane protein Nucleoplasmic side.
Protein Description	Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm). As one of the FG repeat nucleoporins NUP1 is involved in interactions with and guidance of nuclear transport receptors such as SRP1-KAP95 (importin alpha and beta) through the NPC. Like the closely related NUP2 it also plays an important role in disassembling and recycling SRP1-KAP95 to the cytoplasm after nuclear import. Upon entry of the heterotrimeric SRP1-KAP95-cargo complex in the nucleus, NUP1 binds through its C-terminus to KAP95, thus accelerating the release of KAP95 and, indirectly, of the nuclear localization signal (NLS)-containing cargo from the SRP1-KAP95-cargo complex..
Protein Sequence	MSSNTSSVMSSPRVEKRSFSSTLKSFFTNPNKKRPSSKKVFSSNLSYANHLEESDVEDTLHVNKRKRVSGTSQHSDSLTQNNNNAPIIIYGTENTERPPLLPILPIQRLRLLREKQRVRNMRELGLIQSTEFPSITSSVILGSQSKSDEGGSYLCTSSTPSPIKNGSCTRQLAGKSGEDTNVGLPILKSLKNRSNRKRFHSQSKGTVWSANFEYDLSEYDAIQKKDNKDKEGNAGGDQKTSENRNNIKSSISNGNLATGPNLTSEIEDLRADINSNRLSNPQKNLLLKGPASTVAKTAPIQESFVPNSERSGTPTLKKNIEPKKDKESIVLPTVGFDFIKDNETPSKKTSPKATSSAGAVFKSSVEMGKTDKSTKTAEAPTLSFNFSQKANKTKAVDNTVPSTTLFNFGGKSDTVTSASQPFKFGKTSEKSENHTESDAPPKSTAPIFSFGKQEENGDEGDDENEPKRKRRLPVSEDTNTKPLFDFGKTGDQKETKKGESEKDASGKPSFVFGASDKQAEGTPLFTFGKKADVTSNIDSSAQFTFGKAATAKETHTKPSETPATIVKKPTFTFGQSTSENKISEGSAKPTFSFSKSEEERKSSPISNEAAKPSFSFPGKPVDVQAPTDDKTLKPTFSFTEPAQKDSSVVSEPKKPSFTFASSKTSQPKPLFSFGKSDAAKEPPGSNTSFSFTKPPANETDKRPTPPSFTFGGSTTNNTTTTSTKPSFSFGAPESMKSTASTAAANTEKLSNGFSFTKFNHNKEKSNSPTSFFDGSASSTPIPVLGKPTDATGNTTSKSAFSFGTANTNGTNASANSTSFSFNAPATGNGTTTTSNTSGTNIAGTFNVGKPDQSIASGNTNGAGSAFGFSSSGTAATGAASNQSSFNFGNNGAGGLNPFTSATSSTNANAGLFNKPPSTNAQNVNVPSAFNFTGNNSTPGGGSVFNMNGNTNANTVFAGSNNQPHQSQTPSFNTNSSFTPSTVPNINFSGLNGGITNTATNALRPSDIFGANAASGSNSNVTNPSSIFGGAGGVPTTSFGQPQSAPNQMGMGTNNGMSMGGGVMANRKIARMRHSKR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSSNTSSVM ------CCCCCCCCC	43.53	22814378
2	Phosphorylation	------MSSNTSSVM ------CCCCCCCCC	43.53	22369663
3	Phosphorylation	-----MSSNTSSVMS -----CCCCCCCCCC	56.86	22369663
5	Phosphorylation	---MSSNTSSVMSSP ---CCCCCCCCCCCC	25.07	22369663
6	Phosphorylation	--MSSNTSSVMSSPR --CCCCCCCCCCCCC	25.78	22369663
7	Phosphorylation	-MSSNTSSVMSSPRV -CCCCCCCCCCCCCC	21.57	22369663
10	Phosphorylation	SNTSSVMSSPRVEKR CCCCCCCCCCCCCCC	34.73	22369663
11	Phosphorylation	NTSSVMSSPRVEKRS CCCCCCCCCCCCCCC	9.91	22369663
18	Phosphorylation	SPRVEKRSFSSTLKS CCCCCCCCCHHHHHH	40.31	23749301
20	Phosphorylation	RVEKRSFSSTLKSFF CCCCCCCHHHHHHHH	24.53	17563356
21	Phosphorylation	VEKRSFSSTLKSFFT CCCCCCHHHHHHHHC	35.43	21440633
22	Phosphorylation	EKRSFSSTLKSFFTN CCCCCHHHHHHHHCC	36.69	19795423
24	Acetylation	RSFSSTLKSFFTNPN CCCHHHHHHHHCCCC	45.35	24489116
36	Phosphorylation	NPNKKRPSSKKVFSS CCCCCCCCCCCCCCC	59.84	28889911
37	Phosphorylation	PNKKRPSSKKVFSSN CCCCCCCCCCCCCCC	38.90	28889911
42	Phosphorylation	PSSKKVFSSNLSYAN CCCCCCCCCCCCCCC	22.70	20377248
43	Phosphorylation	SSKKVFSSNLSYANH CCCCCCCCCCCCCCC	30.26	22369663
46	Phosphorylation	KVFSSNLSYANHLEE CCCCCCCCCCCCCCC	26.84	20377248
47	Phosphorylation	VFSSNLSYANHLEES CCCCCCCCCCCCCCC	18.00	22369663
54	Phosphorylation	YANHLEESDVEDTLH CCCCCCCCCCCCCEE	37.27	22369663
59	Phosphorylation	EESDVEDTLHVNKRK CCCCCCCCEEECCCC	12.78	20377248
71	Phosphorylation	KRKRVSGTSQHSDSL CCCCCCCCCCCCCCC	20.08	21440633
72	Phosphorylation	RKRVSGTSQHSDSLT CCCCCCCCCCCCCCC	29.44	28889911
77	Phosphorylation	GTSQHSDSLTQNNNN CCCCCCCCCCCCCCC	36.01	19779198
79	Phosphorylation	SQHSDSLTQNNNNAP CCCCCCCCCCCCCCC	32.95	28889911
92	Phosphorylation	APIIIYGTENTERPP CCEEEEECCCCCCCC	14.75	19779198
129	Phosphorylation	RELGLIQSTEFPSIT HHHCCCCCCCCCCCC	23.94	30377154
137	Phosphorylation	TEFPSITSSVILGSQ CCCCCCCCEEEECCC	22.42	30377154
138	Phosphorylation	EFPSITSSVILGSQS CCCCCCCEEEECCCC	12.43	28132839
145	Phosphorylation	SVILGSQSKSDEGGS EEEECCCCCCCCCCC	35.51	30377154
147	Phosphorylation	ILGSQSKSDEGGSYL EECCCCCCCCCCCEE	46.25	22890988
152	Phosphorylation	SKSDEGGSYLCTSST CCCCCCCCEEECCCC	26.28	22890988
153	Phosphorylation	KSDEGGSYLCTSSTP CCCCCCCEEECCCCC	14.74	22890988
156	Phosphorylation	EGGSYLCTSSTPSPI CCCCEEECCCCCCCC	24.10	22890988
157	Phosphorylation	GGSYLCTSSTPSPIK CCCEEECCCCCCCCC	31.08	17330950
158	Phosphorylation	GSYLCTSSTPSPIKN CCEEECCCCCCCCCC	26.61	21082442
159	Phosphorylation	SYLCTSSTPSPIKNG CEEECCCCCCCCCCC	27.79	19823750
161	Phosphorylation	LCTSSTPSPIKNGSC EECCCCCCCCCCCCC	39.07	17330950
167	Phosphorylation	PSPIKNGSCTRQLAG CCCCCCCCCCCCCCC	23.00	21440633
169	Phosphorylation	PIKNGSCTRQLAGKS CCCCCCCCCCCCCCC	24.13	28889911
176	Phosphorylation	TRQLAGKSGEDTNVG CCCCCCCCCCCCCCC	46.64	28889911
188	Acetylation	NVGLPILKSLKNRSN CCCHHHHHHHCCCCC	55.23	24489116
249	Phosphorylation	ENRNNIKSSISNGNL HCHHCCCHHHHCCCC	29.16	22369663
250	Phosphorylation	NRNNIKSSISNGNLA CHHCCCHHHHCCCCC	25.65	25521595
252	Phosphorylation	NNIKSSISNGNLATG HCCCHHHHCCCCCCC	40.40	25521595
258	Phosphorylation	ISNGNLATGPNLTSE HHCCCCCCCCCHHHH	57.23	23749301
263	Phosphorylation	LATGPNLTSEIEDLR CCCCCCHHHHHHHHH	30.84	22369663
264	Phosphorylation	ATGPNLTSEIEDLRA CCCCCHHHHHHHHHH	39.48	22369663
275	Phosphorylation	DLRADINSNRLSNPQ HHHHHHHCCCCCCCC	24.54	22369663
283	Acetylation	NRLSNPQKNLLLKGP CCCCCCCCCEEECCC	51.31	24489116
293	Phosphorylation	LLKGPASTVAKTAPI EECCCCHHCCCCCCC	26.96	19684113
303	Phosphorylation	KTAPIQESFVPNSER CCCCCHHHCCCCCCC	18.37	22369663
308	Phosphorylation	QESFVPNSERSGTPT HHHCCCCCCCCCCCC	28.46	22369663
311	Phosphorylation	FVPNSERSGTPTLKK CCCCCCCCCCCCCCC	42.86	20377248
313	Phosphorylation	PNSERSGTPTLKKNI CCCCCCCCCCCCCCC	17.85	25521595
315	Phosphorylation	SERSGTPTLKKNIEP CCCCCCCCCCCCCCC	51.55	27214570
328	Phosphorylation	EPKKDKESIVLPTVG CCCCCHHCCEEEECC	24.60	21440633
344	Phosphorylation	DFIKDNETPSKKTSP CEECCCCCCCCCCCC	38.83	28889911
346	Phosphorylation	IKDNETPSKKTSPKA ECCCCCCCCCCCCCC	54.96	21440633
349	Phosphorylation	NETPSKKTSPKATSS CCCCCCCCCCCCCCC	54.73	30377154
350	Phosphorylation	ETPSKKTSPKATSSA CCCCCCCCCCCCCCC	33.03	30377154
354	Phosphorylation	KKTSPKATSSAGAVF CCCCCCCCCCCCCEE	29.37	29688323
355	Phosphorylation	KTSPKATSSAGAVFK CCCCCCCCCCCCEEH	24.05	30377154
356	Phosphorylation	TSPKATSSAGAVFKS CCCCCCCCCCCEEHH	26.77	17563356
381	Phosphorylation	TKTAEAPTLSFNFSQ CCCCCCCEEEEECCC	41.92	28889911
383	Phosphorylation	TAEAPTLSFNFSQKA CCCCCEEEEECCCCC	22.18	17563356
387	Phosphorylation	PTLSFNFSQKANKTK CEEEEECCCCCCCCC	31.69	17563356
411	Acetylation	TLFNFGGKSDTVTSA EEEECCCCCCCCCCC	45.60	24489116
419	Phosphorylation	SDTVTSASQPFKFGK CCCCCCCCCCCCCCC	37.85	17563356
423	Acetylation	TSASQPFKFGKTSEK CCCCCCCCCCCCCCC	60.95	24489116
437	Phosphorylation	KSENHTESDAPPKST CCCCCCCCCCCCCCC	39.98	17563356
449	Phosphorylation	KSTAPIFSFGKQEEN CCCCCCEECCCCCCC	33.53	17563356
481	Acetylation	VSEDTNTKPLFDFGK CCCCCCCCCCCCCCC	41.62	24489116
505	Phosphorylation	GESEKDASGKPSFVF CCCCCCCCCCCCEEE	58.44	22369663
509	Phosphorylation	KDASGKPSFVFGASD CCCCCCCCEEECCCC	37.21	24909858
522	Phosphorylation	SDKQAEGTPLFTFGK CCCCCCCCCEEEECC	14.34	28889911
568	Acetylation	TPATIVKKPTFTFGQ CCCEEEECCEEECCC	38.09	22865919
570	Phosphorylation	ATIVKKPTFTFGQST CEEEECCEEECCCCC	44.16	20377248
572	Phosphorylation	IVKKPTFTFGQSTSE EEECCEEECCCCCCC	29.36	20377248
576	Phosphorylation	PTFTFGQSTSENKIS CEEECCCCCCCCCCC	33.99	21440633
578	Phosphorylation	FTFGQSTSENKISEG EECCCCCCCCCCCCC	44.40	21440633
586	Phosphorylation	ENKISEGSAKPTFSF CCCCCCCCCCCCCCC	29.12	24961812
590	Phosphorylation	SEGSAKPTFSFSKSE CCCCCCCCCCCCCCH	31.07	24961812
592	Phosphorylation	GSAKPTFSFSKSEEE CCCCCCCCCCCCHHH	30.96	17563356
594	Phosphorylation	AKPTFSFSKSEEERK CCCCCCCCCCHHHHH	33.79	28889911
595	Acetylation	KPTFSFSKSEEERKS CCCCCCCCCHHHHHC	60.93	24489116
596	Phosphorylation	PTFSFSKSEEERKSS CCCCCCCCHHHHHCC	49.38	28889911
602	Phosphorylation	KSEEERKSSPISNEA CCHHHHHCCCCCCCC	47.79	22369663
603	Phosphorylation	SEEERKSSPISNEAA CHHHHHCCCCCCCCC	29.32	22369663
606	Phosphorylation	ERKSSPISNEAAKPS HHHCCCCCCCCCCCC	31.81	22369663
613	Phosphorylation	SNEAAKPSFSFPGKP CCCCCCCCCCCCCCC	32.58	22369663
615	Phosphorylation	EAAKPSFSFPGKPVD CCCCCCCCCCCCCCC	34.56	20377248
627	Phosphorylation	PVDVQAPTDDKTLKP CCCEECCCCCCCCCC	60.90	22369663
631	Phosphorylation	QAPTDDKTLKPTFSF ECCCCCCCCCCEEEC	47.19	29688323
635	Phosphorylation	DDKTLKPTFSFTEPA CCCCCCCEEECCCCC	30.26	22369663
637	Phosphorylation	KTLKPTFSFTEPAQK CCCCCEEECCCCCCC	33.46	22369663
639	Phosphorylation	LKPTFSFTEPAQKDS CCCEEECCCCCCCCC	39.60	22369663
646	Phosphorylation	TEPAQKDSSVVSEPK CCCCCCCCCCCCCCC	31.87	28889911
647	Phosphorylation	EPAQKDSSVVSEPKK CCCCCCCCCCCCCCC	36.35	17563356
650	Phosphorylation	QKDSSVVSEPKKPSF CCCCCCCCCCCCCCE	46.13	30377154
656	Phosphorylation	VSEPKKPSFTFASSK CCCCCCCCEEEECCC	45.88	17563356
658	Phosphorylation	EPKKPSFTFASSKTS CCCCCCEEEECCCCC	23.72	21440633
661	Phosphorylation	KPSFTFASSKTSQPK CCCEEEECCCCCCCC	28.33	21440633
672	Phosphorylation	SQPKPLFSFGKSDAA CCCCCCEECCCCCCC	40.55	17563356
675	Acetylation	KPLFSFGKSDAAKEP CCCEECCCCCCCCCC	43.05	22865919
676	Phosphorylation	PLFSFGKSDAAKEPP CCEECCCCCCCCCCC	32.63	27017623
685	Phosphorylation	AAKEPPGSNTSFSFT CCCCCCCCCCCCEEC	42.58	28889911
692	Phosphorylation	SNTSFSFTKPPANET CCCCCEECCCCCCCC	41.25	21551504
704	Phosphorylation	NETDKRPTPPSFTFG CCCCCCCCCCCEECC	52.44	28889911
737	Phosphorylation	GAPESMKSTASTAAA CCCHHHHHHHHHHHH	22.14	19779198
738	Phosphorylation	APESMKSTASTAAAN CCHHHHHHHHHHHHH	21.07	19779198
746	Phosphorylation	ASTAAANTEKLSNGF HHHHHHHHHHHCCCC	29.75	19779198
754	Phosphorylation	EKLSNGFSFTKFNHN HHHCCCCCCEECCCC	33.14	22369663
756	Phosphorylation	LSNGFSFTKFNHNKE HCCCCCCEECCCCCC	33.26	22369663
765	Phosphorylation	FNHNKEKSNSPTSFF CCCCCCCCCCCCCCC	43.56	25521595
767	Phosphorylation	HNKEKSNSPTSFFDG CCCCCCCCCCCCCCC	36.32	25521595
769	Phosphorylation	KEKSNSPTSFFDGSA CCCCCCCCCCCCCCC	37.68	22369663
770	Phosphorylation	EKSNSPTSFFDGSAS CCCCCCCCCCCCCCC	27.57	25521595
775	Phosphorylation	PTSFFDGSASSTPIP CCCCCCCCCCCCCCC	27.16	25521595
777	Phosphorylation	SFFDGSASSTPIPVL CCCCCCCCCCCCCCC	36.12	25521595
778	Phosphorylation	FFDGSASSTPIPVLG CCCCCCCCCCCCCCC	37.61	22369663
779	Phosphorylation	FDGSASSTPIPVLGK CCCCCCCCCCCCCCC	23.81	20377248
788	Phosphorylation	IPVLGKPTDATGNTT CCCCCCCCCCCCCCC	41.57	20377248
791	Phosphorylation	LGKPTDATGNTTSKS CCCCCCCCCCCCCCC	33.50	20377248
794	Phosphorylation	PTDATGNTTSKSAFS CCCCCCCCCCCCEEE	33.52	22369663
795	Phosphorylation	TDATGNTTSKSAFSF CCCCCCCCCCCEEEC	37.85	22369663
796	Phosphorylation	DATGNTTSKSAFSFG CCCCCCCCCCEEECE	23.68	22369663

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
383	S	Phosphorylation	Kinase	CHEK2	-	GPS
449	S	Phosphorylation	Kinase	CHEK2	-	GPS
592	S	Phosphorylation	Kinase	CHEK2	-	GPS
615	S	Phosphorylation	Kinase	CHEK2	-	GPS
637	S	Phosphorylation	Kinase	CHEK2	-	GPS
656	S	Phosphorylation	Kinase	CHEK2	-	GPS
672	S	Phosphorylation	Kinase	CHEK2	-	GPS
754	S	Phosphorylation	Kinase	CHEK2	-	GPS

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NUP1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NUP1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
IMA1_YEAST	SRP1	physical	8045927
NU170_YEAST	NUP170	physical	8628268
IMA1_YEAST	SRP1	physical	12917401
IMB1_YEAST	KAP95	physical	12917401
IMB1_YEAST	KAP95	physical	11046143
IMA1_YEAST	SRP1	physical	11046143
IMA1_YEAST	SRP1	physical	10542277
IMB1_YEAST	KAP95	physical	9182759
IMB4_YEAST	KAP123	physical	9182759
NU188_YEAST	NUP188	physical	12496130
MEX67_YEAST	MEX67	physical	12411502
MTR2_YEAST	MTR2	physical	12411502
IMA1_YEAST	SRP1	physical	11387327
IMB1_YEAST	KAP95	physical	11387327
HSP71_YEAST	SSA1	physical	11387327
SSB1_YEAST	SSB1	physical	11387327
PABP_YEAST	PAB1	physical	11387327
IMB1_YEAST	KAP95	physical	9235958
IMB1_YEAST	KAP95	physical	15878174
NUP2_YEAST	NUP2	genetic	12917401
NUP60_YEAST	NUP60	genetic	12917401
NU170_YEAST	NUP170	genetic	8628268
NSP1_YEAST	NSP1	genetic	8443417
IMA1_YEAST	SRP1	genetic	8045927
BRR6_YEAST	BRR6	genetic	11483521
RNA1_YEAST	RNA1	genetic	7929578
NUP60_YEAST	NUP60	genetic	12411502
NUP82_YEAST	NUP82	genetic	15294903
PCY1_YEAST	PCT1	physical	16554755
NCBP1_YEAST	STO1	physical	16554755
ENO2_YEAST	ENO2	physical	16429126
ALF_YEAST	FBA1	physical	16429126
PMG1_YEAST	GPM1	physical	16429126
PGK_YEAST	PGK1	physical	16429126
IMB1_YEAST	KAP95	physical	16429126
IMA1_YEAST	SRP1	physical	16429126
ILV5_YEAST	ILV5	physical	16429126
NU100_YEAST	NUP100	genetic	16118201
ALG12_YEAST	ALG12	genetic	16118201
PO152_YEAST	POM152	genetic	16118201
IMA1_YEAST	SRP1	physical	15741174
IMB1_YEAST	KAP95	physical	15741174
IMB1_YEAST	KAP95	physical	17897934
GLE1_YEAST	GLE1	genetic	18058101
NU170_YEAST	NUP170	genetic	18058101
NUP82_YEAST	NUP82	genetic	18058101
YRB1_YEAST	YRB1	genetic	18058101
IMA1_YEAST	SRP1	genetic	18058101
NUD1_YEAST	NUD1	genetic	18058101
BFA1_YEAST	BFA1	genetic	18058101
BUB2_YEAST	BUB2	genetic	18058101
SSB1_YEAST	SSB1	physical	19536198
MEX67_YEAST	MEX67	physical	19723816
IMA1_YEAST	SRP1	physical	19723816
AVT1_YEAST	AVT1	physical	16093310
ARX1_YEAST	ARX1	physical	17803941
NU192_YEAST	NUP192	physical	18046405
NU188_YEAST	NUP188	physical	18046405
NU170_YEAST	NUP170	physical	18046405
NU157_YEAST	NUP157	physical	18046405
PO152_YEAST	POM152	physical	18046405
NU159_YEAST	NUP159	physical	18046405
NSP1_YEAST	NSP1	physical	18046405
NU120_YEAST	NUP120	physical	18046405
NUP82_YEAST	NUP82	physical	18046405
NUP84_YEAST	NUP84	physical	18046405
NU145_YEAST	NUP145	physical	18046405
IMB1_YEAST	KAP95	physical	18046405
IMA1_YEAST	SRP1	physical	18046405
MLP1_YEAST	MLP1	physical	18046405
NOT4_YEAST	MOT2	genetic	21464899
IMB1_YEAST	KAP95	physical	22357553
IMB3_YEAST	PSE1	physical	22357553
IMB4_YEAST	KAP123	physical	22357553
SAC3_YEAST	SAC3	physical	24705649
CDC31_YEAST	CDC31	physical	24705649
SUS1_YEAST	SUS1	physical	24705649
IMB1_YEAST	KAP95	physical	24705649
BRL1_YEAST	BRL1	genetic	26627736
NU170_YEAST	NUP170	physical	25942622
IMB3_YEAST	PSE1	physical	25942622
NUP2_YEAST	NUP2	physical	25942622
IMB1_YEAST	KAP95	physical	25942622
NUP85_YEAST	NUP85	physical	25942622
GRP78_YEAST	KAR2	physical	25942622
HSP71_YEAST	SSA1	physical	25942622
SSB1_YEAST	SSB1	physical	25942622
NUP60_YEAST	NUP60	physical	25942622
IMA1_YEAST	SRP1	physical	25942622
PO152_YEAST	POM152	genetic	25942622
POM34_YEAST	POM34	genetic	25942622
NUP53_YEAST	NUP53	genetic	25942622
NUP60_YEAST	NUP60	genetic	25942622
MTR2_YEAST	MTR2	physical	23212245
MEX67_YEAST	MEX67	physical	23212245
BUD20_YEAST	BUD20	physical	23212245
GOGA2_HUMAN	GOLGA2	physical	27107014
FXR2_HUMAN	FXR2	physical	27107014

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NUP1_YEAST

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-54; SER-157; SER-158;THR-159; SER-249; SER-252; THR-381; SER-383; SER-509; SER-592;SER-594; SER-637; THR-639; SER-656; SER-754; SER-765; SER-767 ANDTHR-769, AND MASS SPECTROMETRY.	18407956 [Abstract]
"Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-20; SER-252; THR-313;SER-356; SER-383; SER-387; SER-419; SER-437; SER-449; SER-509;THR-572; SER-592; SER-615; SER-656; THR-635; SER-637; SER-647;SER-672; SER-754 AND SER-765, AND MASS SPECTROMETRY.	17563356 [Abstract]
"Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae."; Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.; J. Proteome Res. 6:1190-1197(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-161, AND MASSSPECTROMETRY.	17330950 [Abstract]