YB47_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YB47_YEAST
• UniProt AC: P38306
• Protein Name: Uncharacterized protein YBR197C
• Gene Name: YBR197C
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 217
• Protein Sequence: MGVKQTPPVQVKVSDADSTNRRKSSSQEGNPQLVQLKAKSDKDKRKGSSDSTASIMGSSNALPTKNLTTPPALNPLTTSISRGNTAYERSVNGSRITMHSNLAPTETQDVSWSEIDTLDDVKKMAKEPIVNDGFPRDFESNLTQMRKSHAQLLRLMRERNQRLKYAKLRSPPHKDQHNSATNKDQEPDEVLHDPEIALDGEKYVSQVVDTIKDVHRC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Phosphorylation	PPVQVKVSDADSTNR CCEEEEECCCCCCCC	22.74	27017623
18	Phosphorylation	VKVSDADSTNRRKSS EEECCCCCCCCCCCC	29.33	28889911
19	Phosphorylation	KVSDADSTNRRKSSS EECCCCCCCCCCCCC	33.04	27017623
24	Phosphorylation	DSTNRRKSSSQEGNP CCCCCCCCCCCCCCC	33.15	22369663
25	Phosphorylation	STNRRKSSSQEGNPQ CCCCCCCCCCCCCCC	38.79	22369663
26	Phosphorylation	TNRRKSSSQEGNPQL CCCCCCCCCCCCCCC	39.06	22369663
48	Phosphorylation	DKDKRKGSSDSTASI CCCCCCCCCCCHHHH	33.73	23749301
49	Phosphorylation	KDKRKGSSDSTASIM CCCCCCCCCCHHHHH	44.22	25752575
51	Phosphorylation	KRKGSSDSTASIMGS CCCCCCCCHHHHHCC	28.02	21440633
52	Phosphorylation	RKGSSDSTASIMGSS CCCCCCCHHHHHCCC	29.43	21440633
54	Phosphorylation	GSSDSTASIMGSSNA CCCCCHHHHHCCCCC	17.13	21551504
58	Phosphorylation	STASIMGSSNALPTK CHHHHHCCCCCCCCC	11.75	19823750
59	Phosphorylation	TASIMGSSNALPTKN HHHHHCCCCCCCCCC	22.01	19823750
64	Phosphorylation	GSSNALPTKNLTTPP CCCCCCCCCCCCCCC	33.15	19823750
68	Phosphorylation	ALPTKNLTTPPALNP CCCCCCCCCCCCCCC	46.80	29688323
69	Phosphorylation	LPTKNLTTPPALNPL CCCCCCCCCCCCCCC	30.37	25752575
77	Phosphorylation	PPALNPLTTSISRGN CCCCCCCCCCCCCCC	21.54	29688323
78	Phosphorylation	PALNPLTTSISRGNT CCCCCCCCCCCCCCC	31.57	27017623
79	Phosphorylation	ALNPLTTSISRGNTA CCCCCCCCCCCCCCC	17.21	24930733
81	Phosphorylation	NPLTTSISRGNTAYE CCCCCCCCCCCCCEE	33.62	24909858
97	Phosphorylation	SVNGSRITMHSNLAP CCCCCEEEEECCCCC	14.02	27017623
100	Phosphorylation	GSRITMHSNLAPTET CCEEEEECCCCCCCC	23.79	27017623
148	Phosphorylation	NLTQMRKSHAQLLRL HHHHHHHHHHHHHHH	17.43	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YB47_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YB47_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YB47_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ATG17_YEAST	ATG17	physical	16554755
RV161_YEAST	RVS161	genetic	27708008
GPR1_YEAST	GPR1	genetic	27708008
HKR1_YEAST	HKR1	genetic	27708008
PKR1_YEAST	PKR1	genetic	27708008
KATL1_HUMAN	KATNAL1	physical	27107014

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-26, AND MASSSPECTROMETRY.
PubMed: 18407956