dbPTM

PES4_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PES4_YEAST
UniProt AC	P39684
Protein Name	Protein PES4
Gene Name	PES4
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	611
Subcellular Localization	Nucleus .
Protein Description
Protein Sequence	MYSISNKKPSILSMVPLNILKNQDLKVKKDQEKKISFNPVVTPIRPDDYHEKTSRSSSSSHSDSPEFLRINNNKSGHKNGKLKSFESKKLVPLFIGDLHETVTEETLKGIFKKYPSFVSAKVCLDSVTKKSLGHGYLNFEDKEEAEKAMEELNYTKVNGKEIRIMPSLRNTTFRKNFGTNVFFSNLPLNNPLLTTRVFYDTFSRYGKILSCKLDSRKDIGFVYFEDEKTARNVIKMYNNTSFFGKKILCGIHFDKEVRSVPNFETQKSRLDAETIIEKEQSLNEKHSKGNDKESKNIYSSSQNSIFIKNLPTITTRDDILNFFSEVGPIKSIYLSNATKVKYLWAFVTYKNSSDSEKAIKRYNNFYFRGKKLLVTRAQDKEERAKFIESQKISTLFLENLSAVCNKEFLKYLCHQENIRPFKIQIDGYDENSSTYSGFIKFRNFEDATRIFNFLNNRLVGGSIVTTSWERQNNAPKYHDGYGMRNIHTSSHPQITPYYQYSHANSLNSPHMRDLSSMNSSTRSLIKNKNFNKKVLETFEKQVRRGIDFMRFPSATRDENVHGIAEYIFDTYWNRDVLILDKFLSLLNSSPYHEGVLQKQIEEAASSLGFKR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
60	Phosphorylation	TSRSSSSSHSDSPEF CCCCCCCCCCCCCCE	29.02	27214570
62	Phosphorylation	RSSSSSHSDSPEFLR CCCCCCCCCCCCEEE	41.55	27214570
64	Phosphorylation	SSSSHSDSPEFLRIN CCCCCCCCCCEEEEC	29.37	27214570
520	Phosphorylation	DLSSMNSSTRSLIKN CHHHCCHHHHHHHHC	23.88	27214570

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PES4_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PES4_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PES4_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RIC1_YEAST	RIC1	genetic	19061648
PO152_YEAST	POM152	genetic	19061648
RLA1_YEAST	RPP1A	genetic	27708008
YJY1_YEAST	YJR011C	genetic	27708008
SYG_YEAST	GRS1	genetic	27708008
MCM7_YEAST	MCM7	genetic	27708008
DPOD_YEAST	POL3	genetic	27708008
NSE4_YEAST	NSE4	genetic	27708008
FAL1_YEAST	FAL1	genetic	27708008
SLU7_YEAST	SLU7	genetic	27708008
CDC1_YEAST	CDC1	genetic	27708008
STT3_YEAST	STT3	genetic	27708008
MCE1_YEAST	CEG1	genetic	27708008
DBF2_YEAST	DBF2	genetic	27708008
PRI1_YEAST	PRI1	genetic	27708008
ARP4_YEAST	ARP4	genetic	27708008
CDC6_YEAST	CDC6	genetic	27708008
HSP77_YEAST	SSC1	genetic	27708008
CDC11_YEAST	CDC11	genetic	27708008
SEC22_YEAST	SEC22	genetic	27708008
RSE1_YEAST	RSE1	genetic	27708008
POB3_YEAST	POB3	genetic	27708008
RNA1_YEAST	RNA1	genetic	27708008
DPOA_YEAST	POL1	genetic	27708008
XRN2_YEAST	RAT1	genetic	27708008
NIP7_YEAST	NIP7	genetic	27708008
CET1_YEAST	CET1	genetic	27708008
ARP7_YEAST	ARP7	genetic	27708008
RS6A_YEAST	RPS6B	genetic	27708008
RS6B_YEAST	RPS6B	genetic	27708008
REI1_YEAST	REI1	genetic	27708008
AP3M_YEAST	APM3	genetic	27708008
NHP10_YEAST	NHP10	genetic	27708008
RRP8_YEAST	RRP8	genetic	27708008
URC2_YEAST	URC2	genetic	27708008
RS25A_YEAST	RPS25A	genetic	27708008
OPI1_YEAST	OPI1	genetic	27708008
YRA2_YEAST	YRA2	genetic	27708008
BPT1_YEAST	BPT1	genetic	27708008
YL126_YEAST	YLR126C	genetic	27708008
TOP3_YEAST	TOP3	genetic	27708008
OSW5_YEAST	OSW5	genetic	27708008
TDA1_YEAST	TDA1	genetic	27708008
RRP6_YEAST	RRP6	genetic	27708008
MIP6_YEAST	MIP6	genetic	28193845

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PES4_YEAST

Related Literatures of Post-Translational Modification