YEM4_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YEM4_YEAST
• UniProt AC: P40022
• Protein Name: Uncharacterized protein YER034W
• Gene Name: YER034W
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 185
• Protein Sequence: MDAFSLKKDNRKKFQDKQKLKRKHATPSDRKYRLLNRQKEEKATTEEKDQDQEQPALKSNEDRYYEDPVLEDPHSAVANAELNKVLKDVLKNRLQQNDDATAVNNVANKDTLKIKDLKQMNTDELNRWLGRQNTTSAITAAEPESLVVPIHVQGDHDRAGKKISAPSTDLPEELETDQDFLDGLL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MDAFSLKK -------CCCCCCCC	8.28	22814378
48	Ubiquitination	EKATTEEKDQDQEQP HHCCCHHCCCHHHCC	55.23	23749301
58	Acetylation	DQEQPALKSNEDRYY HHHCCCHHCCCCHHC	54.03	25381059
87	Acetylation	AELNKVLKDVLKNRL HHHHHHHHHHHHHHH	49.10	25381059
109	Acetylation	AVNNVANKDTLKIKD HHHHHCCCCCCCHHH	42.21	24489116
115	Acetylation	NKDTLKIKDLKQMNT CCCCCCHHHHHHCCH	56.26	24489116
122	Phosphorylation	KDLKQMNTDELNRWL HHHHHCCHHHHHHHH	26.05	28889911
167	Phosphorylation	GKKISAPSTDLPEEL CCCCCCCCCCCCHHH	33.98	21440633
176	Phosphorylation	DLPEELETDQDFLDG CCCHHHCCCHHHHHH	52.14	21440633

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YEM4_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YEM4_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YEM4_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UBC3_YEAST	CDC34	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.