dbPTM

YJT3_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YJT3_YEAST
UniProt AC	P39542
Protein Name	Uncharacterized transporter YJL193W
Gene Name	YJL193W
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	402
Subcellular Localization	Membrane Multi-pass membrane protein.
Protein Description
Protein Sequence	MFQQLSASIRHNAHIIFLCISWYFISSLASQVTKQVLTVCPLPLFLGEFQFIYTAVLAWFTCYIAYSFPGFYRIFPNGTFPEYYIDDRETSRAARKESKLSSLIIPPSKPILQTVLPLGLFQFVGKYFGHTATSLVPVSTVASIKTLSPMFILLLQKILKISTLKITLTLIFSLCTLVLGVWIIVQEDNRSPASSNELREFSKYGVICAMISMFIFVLQNIYGKTVFTYRSQTDESQSNSGFSRQESPLPLYEKLDEKLVAKKKPKSYDKLTLMIYISLVGFCLSFGWFITLEFPVLFRYFFQINSSSTVIKAFPVSLFLLNGTFHFIQAMITFHLLGEVSTLTYSIANLMKRFAIIAVSWVFIGRRITWLQVFGLVLNTLGLFLYERCTSQSKIKAKIRPE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MFQQLSASIRHNA --CCHHHHHHHHHCH	18.68	30377154
236	Phosphorylation	YRSQTDESQSNSGFS ECCCCCCCCCCCCCC	41.54	24961812
238	Phosphorylation	SQTDESQSNSGFSRQ CCCCCCCCCCCCCCC	42.09	24961812
240	Phosphorylation	TDESQSNSGFSRQES CCCCCCCCCCCCCCC	46.60	24961812
243	Phosphorylation	SQSNSGFSRQESPLP CCCCCCCCCCCCCCC	36.26	24961812
247	Phosphorylation	SGFSRQESPLPLYEK CCCCCCCCCCCHHHH	24.33	24961812
254	Ubiquitination	SPLPLYEKLDEKLVA CCCCHHHHHCHHHHH	47.91	23749301
254	Acetylation	SPLPLYEKLDEKLVA CCCCHHHHHCHHHHH	47.91	24489116
258	Ubiquitination	LYEKLDEKLVAKKKP HHHHHCHHHHHCCCC	48.18	23749301

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YJT3_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YJT3_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YJT3_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
AEP2_YEAST	AEP2	genetic	27708008
CDK1_YEAST	CDC28	genetic	27708008
PDC2_YEAST	PDC2	genetic	27708008
RSP5_YEAST	RSP5	genetic	27708008
TAD3_YEAST	TAD3	genetic	27708008
HMCS_YEAST	ERG13	genetic	27708008
CAP_YEAST	SRV2	genetic	27708008
GAL10_YEAST	GAL10	genetic	27708008
ODPB_YEAST	PDB1	genetic	27708008
RIM1_YEAST	RIM1	genetic	27708008
THRC_YEAST	THR4	genetic	27708008
S2538_YEAST	YDL119C	genetic	27708008
WHI4_YEAST	WHI4	genetic	27708008
TRS85_YEAST	TRS85	genetic	27708008
RM01_YEAST	MRPL1	genetic	27708008
ATC1_YEAST	PMR1	genetic	27708008
XRN1_YEAST	XRN1	genetic	27708008
RL8A_YEAST	RPL8A	genetic	27708008
HAP4_YEAST	HAP4	genetic	27708008
COXM1_YEAST	CMC1	genetic	27708008
RM49_YEAST	MRP49	genetic	27708008
DCOR_YEAST	SPE1	genetic	27708008
SKI2_YEAST	SKI2	genetic	27708008
ASND1_YEAST	YML096W	genetic	27708008
MSS1_YEAST	MSS1	genetic	27708008
PET8_YEAST	PET8	genetic	27708008
COX5A_YEAST	COX5A	genetic	27708008
PMS1_YEAST	PMS1	genetic	27708008
CY1_YEAST	CYT1	genetic	27708008
COQ7_YEAST	CAT5	genetic	27708008
LIPA_YEAST	LIP5	genetic	27708008
COX10_YEAST	COX10	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YJT3_YEAST

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-247, AND MASSSPECTROMETRY.	18407956 [Abstract]
"Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-247, AND MASSSPECTROMETRY.	17563356 [Abstract]