| UniProt ID | NSI1_YEAST | |
|---|---|---|
| UniProt AC | Q12457 | |
| Protein Name | RNA polymerase I termination factor {ECO:0000303|PubMed:22805593} | |
| Gene Name | NSI1 {ECO:0000303|PubMed:22362748} | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 570 | |
| Subcellular Localization | Nucleus, nucleolus . | |
| Protein Description | DNA-binding protein that recognizes sequence-specific replication termini (Ter sites) within rDNA. [PubMed: 14576157 Binds to rDNA terminator elements and mediates efficient RNA polymerase I transcription termination] | |
| Protein Sequence | MDSVSNLKSTNFQNNNDPKESVEEAVLRYVGVDLKNHIKKTKKKLKKQKKRKHGSKMSHEDEDTDMDWYLKTSGSKDLRKVDDIEPNSVAVAAVAAAYNSSMREKDKRSCHKKSSNSRSERKKHRKRKSSKERKAKIKMVLDPQLTTLDDGITTTAFLPDDLIAETAFDKYVDTEKAYLAKHPSKSLEVNEDDKENNFNNNSSTLVRIYTDLEGIPNDGSYIKRTPKIPEKDVKSDDLILAPEENNGDTALLRSDIVKASVIDGAITKSIGKKFTPSEENALDQFIEEYMKIRGLDRRQMCERIWSTDGVIRDGFWANISKVLPYRTRSSIYKHIRRKYHIFEQRGKWTPEEDQELARLCLEKEGHWTEVGKLLGRMPEDCRDRWRNYMKCGSKRGSKRWSKEEEELLTTVVNEMIEEAHQYQRMKALEAANKNDRYNQMYSRGPKGKRISDNPTFKDMINWTVVSERMSGTRSRIQCRYKWNKLVTDEAARSMLSIPVSERKWLLERLKQLPKTSYSNIDWNSIATYKPGYPRTGLELRLCYEQMREKIHDFKGRSTAEIIDSLLEQIN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 21 | Phosphorylation | NNNDPKESVEEAVLR CCCCHHHHHHHHHHH | 21551504 | ||
| 64 | Phosphorylation | MSHEDEDTDMDWYLK CCCCCCCCCHHHHHH | 28889911 | ||
| 202 | Phosphorylation | ENNFNNNSSTLVRIY CCCCCCCCHHEEEEE | 22369663 | ||
| 203 | Phosphorylation | NNFNNNSSTLVRIYT CCCCCCCHHEEEEEE | 22369663 | ||
| 204 | Phosphorylation | NFNNNSSTLVRIYTD CCCCCCHHEEEEEEC | 22369663 | ||
| 210 | Phosphorylation | STLVRIYTDLEGIPN HHEEEEEECCCCCCC | 23749301 | ||
| 235 | Phosphorylation | IPEKDVKSDDLILAP CCCCCCCCCCEEECC | 28152593 | ||
| 338 | Acetylation | IYKHIRRKYHIFEQR HHHHHHHHHHHHHHC | 25381059 | ||
| 441 | Phosphorylation | NDRYNQMYSRGPKGK CHHHHHHHCCCCCCC | 29734811 | ||
| 493 | Phosphorylation | VTDEAARSMLSIPVS CCHHHHHHHHCCCHH | 27017623 | ||
| 496 | Phosphorylation | EAARSMLSIPVSERK HHHHHHHCCCHHHHH | 27017623 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of NSI1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NSI1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NSI1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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