RL37B_YEAST - dbPTM
RL37B_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RL37B_YEAST
UniProt AC P51402
Protein Name 60S ribosomal protein L37-B {ECO:0000303|PubMed:9559554}
Gene Name RPL37B {ECO:0000303|PubMed:9559554}
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 88
Subcellular Localization Cytoplasm .
Protein Description Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel..
Protein Sequence MGKGTPSFGKRHNKSHTLCNRCGRRSFHVQKKTCSSCGYPSAKTRSHNWAAKAKRRHTTGTGRMRYLKHVSRRFKNGFQTGSAKATSA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
7Phosphorylation-MGKGTPSFGKRHNK
-CCCCCCCCCCCCCC		46.6029734811
15PhosphorylationFGKRHNKSHTLCNRC
CCCCCCCCCCCHHHC		27.3323749301
17PhosphorylationKRHNKSHTLCNRCGR
CCCCCCCCCHHHCCC		39.8523749301
31UbiquitinationRRSFHVQKKTCSSCG
CCEEEECCCCCCCCC		49.3022817900
32UbiquitinationRSFHVQKKTCSSCGY
CEEEECCCCCCCCCC		37.3623749301
33PhosphorylationSFHVQKKTCSSCGYP
EEEECCCCCCCCCCC		25.3422369663
35PhosphorylationHVQKKTCSSCGYPSA
EECCCCCCCCCCCCH		33.6222369663
36PhosphorylationVQKKTCSSCGYPSAK
ECCCCCCCCCCCCHH		17.4422369663
39PhosphorylationKTCSSCGYPSAKTRS
CCCCCCCCCCHHHHC		9.8022369663
41PhosphorylationCSSCGYPSAKTRSHN
CCCCCCCCHHHHCCC		33.6323749301
43UbiquitinationSCGYPSAKTRSHNWA
CCCCCCHHHHCCCHH		49.1323749301
44PhosphorylationCGYPSAKTRSHNWAA
CCCCCHHHHCCCHHH		36.8023749301
46PhosphorylationYPSAKTRSHNWAAKA
CCCHHHHCCCHHHHH		26.8023749301
52AcetylationRSHNWAAKAKRRHTT
HCCCHHHHHHHHCCC		46.8525381059
52UbiquitinationRSHNWAAKAKRRHTT
HCCCHHHHHHHHCCC		46.8522817900
54UbiquitinationHNWAAKAKRRHTTGT
CCHHHHHHHHCCCCC		49.6222817900
75UbiquitinationKHVSRRFKNGFQTGS
HHHHHHHHCCCCCCC		55.1122817900
75AcetylationKHVSRRFKNGFQTGS
HHHHHHHHCCCCCCC		55.11-
80PhosphorylationRFKNGFQTGSAKATS
HHHCCCCCCCCCCCC		30.7323749301
82PhosphorylationKNGFQTGSAKATSA-
HCCCCCCCCCCCCC-		29.9523749301
84UbiquitinationGFQTGSAKATSA---
CCCCCCCCCCCC---		54.6223749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RL37B_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RL37B_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RL37B_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ETR1_YEASTETR1genetic
20093466
CGR1_YEASTCGR1genetic
20093466
STB5_YEASTSTB5genetic
20093466
SDHX_YEASTYJL045Wgenetic
20093466
MET5_YEASTMET5genetic
20093466
LDB18_YEASTLDB18genetic
20093466
RL37A_YEASTRPL37Agenetic
20093466
GBLP_YEASTASC1genetic
20093466
INO4_YEASTINO4genetic
20093466
SIR2_YEASTSIR2genetic
21902802
MED6_YEASTMED6genetic
27708008
CLP1_YEASTCLP1genetic
27708008
CGR1_YEASTCGR1genetic
27708008
INO4_YEASTINO4genetic
27708008
TECR_YEASTTSC13genetic
27708008
PRS8_YEASTRPT6genetic
27708008
RPN1_YEASTRPN1genetic
27708008
DYR_YEASTDFR1genetic
27708008
PSB5_YEASTPRE2genetic
27708008
ETR1_YEASTETR1genetic
27708008
EDS1_YEASTEDS1genetic
27708008
ADPP_YEASTYSA1genetic
27708008
VAM7_YEASTVAM7genetic
27708008
STB5_YEASTSTB5genetic
27708008
MGA2_YEASTMGA2genetic
27708008
MET5_YEASTMET5genetic
27708008
RL37A_YEASTRPL37Agenetic
27708008
GBLP_YEASTASC1genetic
27708008
YNO0_YEASTYNL140Cgenetic
27708008
VAM3_YEASTVAM3genetic
27708008
SUR1_YEASTSUR1genetic
27708008
GGPPS_YEASTBTS1genetic
27708008
DOM34_YEASTDOM34genetic
29158977
RL36A_YEASTRPL36Agenetic
29158977
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RL37B_YEAST

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Related Literatures of Post-Translational Modification

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