HLR1_YEAST - dbPTM
HLR1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HLR1_YEAST
UniProt AC Q04429
Protein Name Protein HLR1
Gene Name HLR1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 423
Subcellular Localization Cytoplasm .
Protein Description Involved in cell wall composition and integrity and response to osmotic stress..
Protein Sequence MENLCPPPPSQMKDFSTPPRNRHRHKRSFAISGDFEFLKQPASAPVLPSAYDSPTFENTPRRVSGMSVTMPDESQNESALLNSPSPRFFISEASTYSSPIKGVPDAIINLDDVLINKPKMCRSHRKTKSVPVKLDEFYSSHKCSSVPELTINEEIDEDDTNPQLLEPVKPLSSTSLSTDMNEDKKMTLKNARSHNSLKIQAQKQRYYNSARYLPLNSEDRATDPQILTKQSSVTSLFSSRSITPVSCNINNAGRINAISGNYLDDVLYDLDTPATTLIQDIDNLQTSINERVRLSPQSSSIKKYFSKDGKSVSSFNFQSQECDMVSFTEDFAHVTSLSSSILDSEKQTDDEEEESIPEEILRGEPLHVYNETSGSDKSVILPTKQKSAPINKDSKHSSTQYEEKSFKKNRKFKIFAKLFCTRK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
17PhosphorylationSQMKDFSTPPRNRHR
HHCCCCCCCCCCCCC		36.9925704821
28PhosphorylationNRHRHKRSFAISGDF
CCCCCCCCEEEECCC		24.6728132839
32PhosphorylationHKRSFAISGDFEFLK
CCCCEEEECCCHHHC		28.9628132839
49PhosphorylationASAPVLPSAYDSPTF
CCCCCCCCCCCCCCC		34.9923749301
53PhosphorylationVLPSAYDSPTFENTP
CCCCCCCCCCCCCCC		17.1127017623
55PhosphorylationPSAYDSPTFENTPRR
CCCCCCCCCCCCCCC		47.7527017623
59PhosphorylationDSPTFENTPRRVSGM
CCCCCCCCCCCCCCC		15.8127017623
83PhosphorylationNESALLNSPSPRFFI
CHHHHHCCCCCCEEE		27.0719684113
85PhosphorylationSALLNSPSPRFFISE
HHHHCCCCCCEEEEE		28.6419684113
94PhosphorylationRFFISEASTYSSPIK
CEEEEECCCCCCCCC		24.6727017623
95PhosphorylationFFISEASTYSSPIKG
EEEEECCCCCCCCCC		34.1827017623
96PhosphorylationFISEASTYSSPIKGV
EEEECCCCCCCCCCC		12.4927017623
97PhosphorylationISEASTYSSPIKGVP
EEECCCCCCCCCCCC		29.7127017623
98PhosphorylationSEASTYSSPIKGVPD
EECCCCCCCCCCCCC		21.8927017623
129PhosphorylationRSHRKTKSVPVKLDE
CCCCCCCCCCCCHHH		36.5621440633
196PhosphorylationKNARSHNSLKIQAQK
HHHHHCCCHHHHHHH		26.1423749301
228PhosphorylationATDPQILTKQSSVTS
CCCHHHHCCHHHCHH		28.7723749301
229UbiquitinationTDPQILTKQSSVTSL
CCHHHHCCHHHCHHH		44.7423749301
231PhosphorylationPQILTKQSSVTSLFS
HHHHCCHHHCHHHHC		28.4723749301
232PhosphorylationQILTKQSSVTSLFSS
HHHCCHHHCHHHHCC		27.2423749301
235PhosphorylationTKQSSVTSLFSSRSI
CCHHHCHHHHCCCCC		25.8423749301
239PhosphorylationSVTSLFSSRSITPVS
HCHHHHCCCCCCEEE		23.7828889911
241PhosphorylationTSLFSSRSITPVSCN
HHHHCCCCCCEEEEE		32.5328889911
243PhosphorylationLFSSRSITPVSCNIN
HHCCCCCCEEEEECC		20.9124930733
295PhosphorylationINERVRLSPQSSSIK
HHHHHCCCCCCHHHH		15.4419684113
298PhosphorylationRVRLSPQSSSIKKYF
HHCCCCCCHHHHHHH		29.4528889911
299PhosphorylationVRLSPQSSSIKKYFS
HCCCCCCHHHHHHHC		30.7319684113
300PhosphorylationRLSPQSSSIKKYFSK
CCCCCCHHHHHHHCC		43.6119684113
355PhosphorylationTDDEEEESIPEEILR
CCCCHHHCCCHHHHC		46.8828889911
369PhosphorylationRGEPLHVYNETSGSD
CCCCEEEEECCCCCC		9.1328889911
372PhosphorylationPLHVYNETSGSDKSV
CEEEEECCCCCCCEE		34.4527017623
373PhosphorylationLHVYNETSGSDKSVI
EEEEECCCCCCCEEE		30.0728889911
375PhosphorylationVYNETSGSDKSVILP
EEECCCCCCCEEEEE		41.4523749301
378PhosphorylationETSGSDKSVILPTKQ
CCCCCCCEEEEECCC		21.2725704821
383PhosphorylationDKSVILPTKQKSAPI
CCEEEEECCCCCCCC		42.5427017623
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of HLR1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HLR1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HLR1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SRO77_YEASTSRO77genetic
27708008
VAM6_YEASTVAM6genetic
27708008
PAA1_YEASTPAA1genetic
27708008
NUM1_YEASTNUM1genetic
27708008
RPA14_YEASTRPA14genetic
27708008
FMP48_YEASTFMP48genetic
27708008
RS10B_YEASTRPS10Bgenetic
27708008
IZH2_YEASTIZH2genetic
27708008
NIP80_YEASTNIP100genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HLR1_YEAST

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Related Literatures of Post-Translational Modification

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