AQR1_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AQR1_YEAST
• UniProt AC: P53943
• Protein Name: Probable transporter AQR1
• Gene Name: AQR1
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 586
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Description: Probable transporter that confers resistance to short-chain monocarboxylic acids and quinidine..
• Protein Sequence: MSRSNSIYTEDIEMYPTHNEQHLTREYTKPDGQTKSEKLNFEGAYINSHGTLSKTTTREIEGDLDSETSSHSSDDKVDPTQQITAETKAPYTLLSYGQKWGMVAILTMCGFWSSLGSPIYYPALRQLEKQFNVDENMVNVTVVVYLLFQGISPTVSGGLADCFGRRPIILAGMLIYVIASIGLACAPSYGVIIFLRCIQSIGISPTIAISSGVVGDFTLKHERGTFVGATSGFVLLGQCFGSLIGAVLTARWDWRAIFWFLTIGCGSCFLIAFLILPETKRTIAGNLSIKPKRFINRAPIFLLGPVRRRFKYDNPDYETLDPTIPKLDLSSAGKILVLPEIILSLFPSGLLFAMWTLMLSSISSGLSVAPYNYHLVIIGVCYLPGGIGGLMGSFFTGRIIDMYFKRKIKKFEQDKANGLIPQDAEINMFKVRLVCLLPQNFLAVVAYLLFGWSIDKGWRIESILITSFVCSYCAMSTLSTSTTLLVDLYPTKSSTASSCFNFVRCSLSTIFMGCFAKMKAAMTVGGTFTFLCALVFFFNFLMFIPMKYGMKWREDRLLKQQRQSWLNTLAVKAKKGTKRDQNDNHN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSRSNSIYT ------CCCCCCCCC	44.40	28889911
4	Phosphorylation	----MSRSNSIYTED ----CCCCCCCCCCC	27.85	28889911
6	Phosphorylation	--MSRSNSIYTEDIE --CCCCCCCCCCCCC	20.44	28889911
8	Phosphorylation	MSRSNSIYTEDIEMY CCCCCCCCCCCCCCC	12.14	19779198
9	Phosphorylation	SRSNSIYTEDIEMYP CCCCCCCCCCCCCCC	26.05	25704821
28	Phosphorylation	QHLTREYTKPDGQTK CCCCEEECCCCCCCC	31.20	23749301
29	Ubiquitination	HLTREYTKPDGQTKS CCCEEECCCCCCCCC	39.96	23749301
35	Ubiquitination	TKPDGQTKSEKLNFE CCCCCCCCCCCCCCC	49.05	23749301
38	Ubiquitination	DGQTKSEKLNFEGAY CCCCCCCCCCCCCEE	56.68	23749301
51	Phosphorylation	AYINSHGTLSKTTTR EEECCCCCCCCCEEC	23.57	19779198
53	Phosphorylation	INSHGTLSKTTTREI ECCCCCCCCCEECEE	28.00	25704821
54	Ubiquitination	NSHGTLSKTTTREIE CCCCCCCCCEECEEE	53.67	23749301
72	Phosphorylation	DSETSSHSSDDKVDP CCCCCCCCCCCCCCC	37.09	27017623
73	Phosphorylation	SETSSHSSDDKVDPT CCCCCCCCCCCCCCC	44.39	27017623
80	Phosphorylation	SDDKVDPTQQITAET CCCCCCCCHHCCCCC	28.74	27017623
84	Phosphorylation	VDPTQQITAETKAPY CCCCHHCCCCCCCCE	17.69	27017623
87	Phosphorylation	TQQITAETKAPYTLL CHHCCCCCCCCEEEH	30.00	27017623
95	Phosphorylation	KAPYTLLSYGQKWGM CCCEEEHHHHHHHHH	30.26	27017623
96	Phosphorylation	APYTLLSYGQKWGMV CCEEEHHHHHHHHHH	24.44	27017623
290	Ubiquitination	IAGNLSIKPKRFINR HCCCCCCCCCCCCCC	40.90	17644757
292	Ubiquitination	GNLSIKPKRFINRAP CCCCCCCCCCCCCCC	55.74	17644757

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AQR1_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AQR1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AQR1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CDC48_YEAST	CDC48	genetic	27708008
SLU7_YEAST	SLU7	genetic	27708008
RSP5_YEAST	RSP5	genetic	27708008
ACT_YEAST	ACT1	genetic	27708008
ZPR1_YEAST	ZPR1	genetic	27708008
RRP4_YEAST	RRP4	genetic	27708008
PAN1_YEAST	PAN1	genetic	27708008
RRN7_YEAST	RRN7	genetic	27708008
CDC11_YEAST	CDC11	genetic	27708008
SN114_YEAST	SNU114	genetic	27708008
RU1C_YEAST	YHC1	genetic	27708008
PRP24_YEAST	PRP24	genetic	27708008
NUF2_YEAST	NUF2	genetic	27708008
YTM1_YEAST	YTM1	genetic	27708008
ASA1_YEAST	ASA1	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.