dbPTM

CCHL_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CCHL_YEAST
UniProt AC	P06182
Protein Name	Cytochrome c heme lyase
Gene Name	CYC3
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	269
Subcellular Localization	Mitochondrion inner membrane. Mitochondrion intermembrane space .
Protein Description	Links covalently the heme group to the apoprotein of cytochrome c..
Protein Sequence	MGWFWADQKTTGKDIGGAAVSSMSGCPVMHESSSSSPPSSECPVMQGDNDRINPLNNMPELAASKQPGQKMDLPVDRTISSIPKSPDSNEFWEYPSPQQMYNAMVRKGKIGGSGEVAEDAVESMVQVHNFLNEGCWQEVLEWEKPHTDESHVQPKLLKFMGKPGVLSPRARWMHLCGLLFPSHFSQELPFDRHDWIVLRGERKAEQQPPTFKEVRYVLDFYGGPDDENGMPTFHVDVRPALDSLDNAKDRMTRFLDRMISGPSSSSSAP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
70	Ubiquitination	ASKQPGQKMDLPVDR HCCCCCCCCCCCCCC	40.05	23749301
85	Phosphorylation	TISSIPKSPDSNEFW CHHHCCCCCCCCCCC	28.69	27017623
88	Phosphorylation	SIPKSPDSNEFWEYP HCCCCCCCCCCCCCC	41.46	21440633
94	Phosphorylation	DSNEFWEYPSPQQMY CCCCCCCCCCHHHHH	10.29	27017623

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CCHL_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CCHL_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CCHL_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
COX15_YEAST	COX15	genetic	11959116
ERV1_YEAST	ERV1	genetic	17972915
CYC2_YEAST	CYC2	genetic	20697122
CCHL_YEAST	CYC3	physical	22257001
CDC37_YEAST	CDC37	genetic	27708008
UTP5_YEAST	UTP5	genetic	27708008
ACT_YEAST	ACT1	genetic	27708008
DNA2_YEAST	DNA2	genetic	27708008
CAP_YEAST	SRV2	genetic	27708008
TIM23_YEAST	TIM23	genetic	27708008
SYA_YEAST	ALA1	genetic	27708008
PSB5_YEAST	PRE2	genetic	27708008
SNC2_YEAST	SNC2	genetic	27708008
SEC17_YEAST	SEC17	genetic	27708008
ALG1_YEAST	ALG1	genetic	27708008
MAK5_YEAST	MAK5	genetic	27708008
POP7_YEAST	POP7	genetic	27708008
MED8_YEAST	MED8	genetic	27708008
CDC10_YEAST	CDC10	genetic	27708008
SCC1_YEAST	MCD1	genetic	27708008
TIM22_YEAST	TIM22	genetic	27708008
DAD1_YEAST	DAD1	genetic	27708008
SLU7_YEAST	SLU7	genetic	27708008
TCPZ_YEAST	CCT6	genetic	27708008
TCPA_YEAST	TCP1	genetic	27708008
PCF11_YEAST	PCF11	genetic	27708008
TRS23_YEAST	TRS23	genetic	27708008
TFC6_YEAST	TFC6	genetic	27708008
RSP5_YEAST	RSP5	genetic	27708008
PP12_YEAST	GLC7	genetic	27708008
TBP_YEAST	SPT15	genetic	27708008
COG3_YEAST	COG3	genetic	27708008
USE1_YEAST	USE1	genetic	27708008
MCE1_YEAST	CEG1	genetic	27708008
PRP18_YEAST	PRP18	genetic	27708008
SMD1_YEAST	SMD1	genetic	27708008
CBF3A_YEAST	CBF2	genetic	27708008
RHO3_YEAST	RHO3	genetic	27708008
CYAA_YEAST	CYR1	genetic	27708008
TAD2_YEAST	TAD2	genetic	27708008
TIM16_YEAST	PAM16	genetic	27708008
SSL1_YEAST	SSL1	genetic	27708008
RSC58_YEAST	RSC58	genetic	27708008
BOS1_YEAST	BOS1	genetic	27708008
RU1C_YEAST	YHC1	genetic	27708008
RNA14_YEAST	RNA14	genetic	27708008
LST8_YEAST	LST8	genetic	27708008
MED7_YEAST	MED7	genetic	27708008
TOA1_YEAST	TOA1	genetic	27708008
CLP1_YEAST	CLP1	genetic	27708008
TFC8_YEAST	TFC8	genetic	27708008
COPZ_YEAST	RET3	genetic	27708008
GPI2_YEAST	GPI2	genetic	27708008
CET1_YEAST	CET1	genetic	27708008
RV161_YEAST	RVS161	genetic	27708008
GPR1_YEAST	GPR1	genetic	27708008
PEX19_YEAST	PEX19	genetic	27708008
PAA1_YEAST	PAA1	genetic	27708008
PMP3_YEAST	PMP3	genetic	27708008
SDS3_YEAST	SDS3	genetic	27708008
RL16A_YEAST	RPL16A	genetic	27708008
PTK2_YEAST	PTK2	genetic	27708008
VPS24_YEAST	VPS24	genetic	27708008
BAS1_YEAST	BAS1	genetic	27708008
ERG3_YEAST	ERG3	genetic	27708008
SRN2_YEAST	SRN2	genetic	27708008
ATP10_YEAST	ATP10	genetic	27708008
TSA1_YEAST	TSA1	genetic	27708008
ATP18_YEAST	ATP18	genetic	27708008
PFKA2_YEAST	PFK2	genetic	27708008
SIW14_YEAST	SIW14	genetic	27708008
MKS1_YEAST	MKS1	genetic	27708008
CARME_YEAST	YNL092W	genetic	27708008
VPS27_YEAST	VPS27	genetic	27708008
ATP23_YEAST	ATP23	genetic	27708008
SUR1_YEAST	SUR1	genetic	27708008
VPS4_YEAST	VPS4	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CCHL_YEAST

Related Literatures of Post-Translational Modification