| UniProt ID | FIN1_YEAST | |
|---|---|---|
| UniProt AC | Q03898 | |
| Protein Name | Filament protein FIN1 | |
| Gene Name | FIN1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 291 | |
| Subcellular Localization | Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, spindle pole . Nuclear during early bud formation, located at the spindle poles during late mitosis, very low abundance in resting cells. | |
| Protein Description | Forms cell-cycle specific filaments between the spindle pole bodies of dividing yeast cells.. | |
| Protein Sequence | MSNKSNRRSLRDIGNTIGRNNIPSDKDNVFVRLSMSPLRTTSQKEFLKPPMRISPNKTDGMKHSIQVTPRRIMSPECLKGYVSKETQSLDRPQFKNSNKNVKIQNSDHITNIIFPTSPTKLTFSNENKIGGDGSLTRIRARFKNGLMSPERIQQQQQQHILPSDAKSNTDLCSNTELKDAPFENDLPRAKLKGKNLLVELKKEEEDVGNGIESLTKSNTKLNSMLANEGKIHKASFQKSVKFKLPDNIVTEETVELKEIKDLLLQMLRRQREIESRLSNIELQLTEIPKHK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 26 | Ubiquitination | RNNIPSDKDNVFVRL CCCCCCCCCCEEEEE | 56.38 | 23749301 | |
| 34 | Phosphorylation | DNVFVRLSMSPLRTT CCEEEEECCCCCCCC | 13.47 | 22369663 | |
| 36 | Phosphorylation | VFVRLSMSPLRTTSQ EEEEECCCCCCCCCH | 19.87 | 22369663 | |
| 40 | Phosphorylation | LSMSPLRTTSQKEFL ECCCCCCCCCHHHHC | 38.18 | 24961812 | |
| 41 | Phosphorylation | SMSPLRTTSQKEFLK CCCCCCCCCHHHHCC | 23.79 | 24961812 | |
| 42 | Phosphorylation | MSPLRTTSQKEFLKP CCCCCCCCHHHHCCC | 38.35 | 24961812 | |
| 54 | Phosphorylation | LKPPMRISPNKTDGM CCCCCEECCCCCCCC | 16.44 | 17173039 | |
| 68 | Phosphorylation | MKHSIQVTPRRIMSP CCCCCEECCCEECCH | 8.49 | 17173039 | |
| 74 | Phosphorylation | VTPRRIMSPECLKGY ECCCEECCHHHHHHH | 18.38 | 21082442 | |
| 86 | Phosphorylation | KGYVSKETQSLDRPQ HHHCCHHHCCCCCHH | 27.48 | 25752575 | |
| 88 | Phosphorylation | YVSKETQSLDRPQFK HCCHHHCCCCCHHHC | 39.39 | 19823750 | |
| 102 | Ubiquitination | KNSNKNVKIQNSDHI CCCCCCCEECCCCCC | 48.22 | 17644757 | |
| 116 | Phosphorylation | ITNIIFPTSPTKLTF CEEEEECCCCCEEEE | 36.27 | 22369663 | |
| 117 | Phosphorylation | TNIIFPTSPTKLTFS EEEEECCCCCEEEEC | 30.70 | 22369663 | |
| 119 | Phosphorylation | IIFPTSPTKLTFSNE EEECCCCCEEEECCC | 38.15 | 20377248 | |
| 120 | Ubiquitination | IFPTSPTKLTFSNEN EECCCCCEEEECCCC | 49.25 | 17644757 | |
| 134 | Phosphorylation | NKIGGDGSLTRIRAR CCCCCCCCCHHHHHH | 31.16 | 27214570 | |
| 148 | Phosphorylation | RFKNGLMSPERIQQQ HHHCCCCCHHHHHHH | 28.75 | 22369663 | |
| 163 | Phosphorylation | QQQHILPSDAKSNTD HHHCCCCCCCCCCCC | 46.91 | 20377248 | |
| 166 | Ubiquitination | HILPSDAKSNTDLCS CCCCCCCCCCCCCCC | 49.59 | 17644757 | |
| 194 | Ubiquitination | PRAKLKGKNLLVELK CHHHHCCCEEEEEEH | 42.72 | 17644757 | |
| 201 | Ubiquitination | KNLLVELKKEEEDVG CEEEEEEHHHHHHHH | 44.63 | 17644757 | |
| 202 | Ubiquitination | NLLVELKKEEEDVGN EEEEEEHHHHHHHHC | 80.92 | 17644757 | |
| 216 | Ubiquitination | NGIESLTKSNTKLNS CHHHHHHHCCHHHHH | 47.18 | 17644757 | |
| 235 | Phosphorylation | EGKIHKASFQKSVKF CCCCCHHHHHCCCCE | 32.77 | 21126336 |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of FIN1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of FIN1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-74, AND MASSSPECTROMETRY. | |
| "Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-88 AND SER-117, AND MASSSPECTROMETRY. | |
| "Analysis of phosphorylation sites on proteins from Saccharomycescerevisiae by electron transfer dissociation (ETD) massspectrometry."; Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L.,Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.; Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-54; THR-68; SER-74;SER-88 AND SER-148, AND MASS SPECTROMETRY. | |
