| UniProt ID | ISR1_YEAST | |
|---|---|---|
| UniProt AC | Q06098 | |
| Protein Name | Serine/threonine-protein kinase ISR1 | |
| Gene Name | ISR1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 443 | |
| Subcellular Localization | ||
| Protein Description | Probable serine/threonine protein kinase which may function redundantly with MPK1-independent branch of the PCK1 pathway that is presumed to be required for the tolerance to high temperatures and staurosporine.. | |
| Protein Sequence | MNSTPPTSPVTRVSDGSFPSISNNSKGFAYRQPQKHKSNFAYSHLVSPVEEPTAKFSEAFQTDYSSKAPVATSEAHLKNDLDVLFTTPRFYSPENLALMFRLSNTVSSLEFLDEFLMGILLAPEMDFLSNPSYSLPSNKLVGQGSYSYVYPISSSASSRCNNDSGVVLKFAKSQHKSKVILQEALTLAYLQYMSPSTNESHIIPFYGLTYITKSHFRRLRSNECVPGLILPKCEMSLYHFNTAVSHKLSLITKRKIWWRLMKQMIDALKSLKTNGIIHGDIKTANILITEMHVLNGGHCKDFDFYLADFTSAFHINQTPTDLNTTVEYCAPELIDSSSDHVPTFESDLYAVGLCLLSFISQHEPYNELQALVSHGSSPGIGSSSIQQSQWLINALLKKDPINLNMLRNDLFQDWKSELALLSRILVDRLPLENLITILDSNYI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MNSTPPTSPV -----CCCCCCCCCC | 40.78 | 28889911 | |
| 4 | Phosphorylation | ----MNSTPPTSPVT ----CCCCCCCCCCC | 28.43 | 28889911 | |
| 7 | Phosphorylation | -MNSTPPTSPVTRVS -CCCCCCCCCCCCCC | 47.03 | 28152593 | |
| 8 | Phosphorylation | MNSTPPTSPVTRVSD CCCCCCCCCCCCCCC | 24.13 | 28889911 | |
| 11 | Phosphorylation | TPPTSPVTRVSDGSF CCCCCCCCCCCCCCC | 28.83 | 28889911 | |
| 26 | Ubiquitination | PSISNNSKGFAYRQP CCCCCCCCCCCCCCC | 61.24 | 23749301 | |
| 47 | Phosphorylation | FAYSHLVSPVEEPTA CCCCCCCCCCCCCCH | 29.59 | 28889911 | |
| 398 | Ubiquitination | LINALLKKDPINLNM HHHHHHHCCCCCHHH | 69.57 | 22106047 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ISR1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ISR1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ISR1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
