| UniProt ID | GLE2_YEAST | |
|---|---|---|
| UniProt AC | P40066 | |
| Protein Name | Nucleoporin GLE2 | |
| Gene Name | GLE2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 365 | |
| Subcellular Localization |
Nucleus, nuclear pore complex. Nucleus membrane Peripheral membrane protein Cytoplasmic side. Nucleus membrane Peripheral membrane protein Nucleoplasmic side. Symmetric distribution. |
|
| Protein Description | Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. It is specifically important for nuclear mRNA export.. | |
| Protein Sequence | MSFFNRSNTTSALGTSTAMANEKDLANDIVINSPAEDSISDIAFSPQQDFMFSASSWDGKVRIWDVQNGVPQGRAQHESSSPVLCTRWSNDGTKVASGGCDNALKLYDIASGQTQQIGMHSAPIKVLRFVQCGPSNTECIVTGSWDKTIKYWDMRQPQPVSTVMMPERVYSMDNKQSLLVVATAERHIAIINLANPTTIFKATTSPLKWQTRCVACYNEADGYAIGSVEGRCSIRYIDDGMQKKSGFSFKCHRQTNPNRAPGSNGQSLVYPVNSIAFHPLYGTFVTAGGDGTFNFWDKNQRHRLKGYPTLQASIPVCSFNRNGSVFAYALSYDWHQGHMGNRPDYPNVIRLHATTDEEVKEKKKR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSFFNRSNT ------CCCCCCCCC | 38.25 | 30377154 | |
| 7 | Phosphorylation | -MSFFNRSNTTSALG -CCCCCCCCCCCCCC | 39.36 | 30377154 | |
| 9 | Phosphorylation | SFFNRSNTTSALGTS CCCCCCCCCCCCCCH | 24.31 | 28889911 | |
| 10 | Phosphorylation | FFNRSNTTSALGTST CCCCCCCCCCCCCHH | 19.09 | 30377154 | |
| 11 | Phosphorylation | FNRSNTTSALGTSTA CCCCCCCCCCCCHHH | 21.32 | 30377154 | |
| 15 | Phosphorylation | NTTSALGTSTAMANE CCCCCCCCHHHCCCH | 24.61 | 30377154 | |
| 79 | Phosphorylation | QGRAQHESSSPVLCT CCCCCCCCCCCEEEE | 33.71 | 30377154 | |
| 80 | Phosphorylation | GRAQHESSSPVLCTR CCCCCCCCCCEEEEE | 35.36 | 23749301 | |
| 81 | Phosphorylation | RAQHESSSPVLCTRW CCCCCCCCCEEEEEE | 28.45 | 21440633 | |
| 161 | Phosphorylation | MRQPQPVSTVMMPER CCCCCCCEEEECCCE | 23.20 | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GLE2_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GLE2_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GLE2_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-81, AND MASSSPECTROMETRY. | |
